Protein Alignment CG32473 and CG5849

DIOPT Version :9

• Sequence 1: NP_731787.1
• Gene: CG32473 / 41636
• FlyBaseID: FBgn0052473
• Length: 1025
• Species: Drosophila melanogaster
• Sequence 2: NP_650979.1
• Gene: CG5849 / 42556
• FlyBaseID: FBgn0038897
• Length: 968
• Species: Drosophila melanogaster
• Alignment Length: 943
• Identity: 252/943 - (26%)
• Similarity: 414/943 - (43%)
• Gaps: 112/943 - (11%)

  Fly   143 RLPKQIKPSKYRLHLRPDLERKN--YSGNISISLQVLEPIAFIPVHVKQLNVSTVEVKRLDESGA 205
            |||....|..|:||:..|:.:..  :|||.:|.:.:.:....|.:|.|.|....:.|.||...|:
  Fly    30 RLPNATYPLFYQLHISSDIHKGQLLFSGNATIDVAIRQSTNEIVLHAKNLTDIQITVHRLMAEGS 94

  Fly   206 PLKD-----ITPT--LTFAHPEFEYWVTEFEQPLEAGNYSLLLNFTGSLVDRITGMYQSSYLDKL 263
            .:.|     :.||  |...||...|...|     |...|.|.:.:|..:..|..|:|...|.|:.
  Fly    95 EIVDDLTHTLHPTAALLIIHPIENYQAFE-----EGQQYRLEILYTAIMASRPAGLYYMDYRDEE 154

  Fly   264 KNRSRSIISTKFEPTYARQAFPCFDEPALKAQFTITVARPSGDEYHVLSNMPVASEYVDGDITEV 328
            .|.:..:.:|:.||||.|..|||:|||..|:.|:|.:..  |..:..:|||||......||:...
  Fly   155 NNHTVYVAATQCEPTYGRLIFPCYDEPGFKSNFSIKITH--GSSHSAISNMPVKEVLAHGDLKTT 217

  Fly   329 TFAETVPMSTYLAAFVVSDFQYKETTVEGTSIALKVYAPPAQVEKTQYALDTAAGVMAYYINYFN 393
            :|..|.|:||||.|||:|||.....|..|  |...:|..|...||.|.||..|...:|...:||.
  Fly   218 SFHTTPPISTYLVAFVISDFGSISETYRG--ITQSIYTSPTSKEKGQVALKNAVRTVAALEDYFG 280

  Fly   394 VSYALPKLDLVAIPDFVSGAMENWGLVTFRETALLYDESTSSSVNKQRVAIVVA-HELAHQWFGN 457
            |||.|||||.||:......|||||||:|:::..||  ::.||...|:::.::.. ||:|||||||
  Fly   281 VSYPLPKLDHVALKKNYGAAMENWGLITYKDVNLL--KNISSDGQKRKLDLITQNHEIAHQWFGN 343

  Fly   458 LVTMNWWNDLWLNEGFASFLEYKGVKQMHPEWDMDNQFVIEELHPVLTIDATLASHPIVKSIESP 522
            ||:..||...|:|||||::..|.....::|...|.:.|:..|.....:.::....||:...:|..
  Fly   344 LVSPEWWTYTWMNEGFATYFSYVITDLIYPNDKMMDMFMTHEADSAYSYNSFFDVHPMSHYVEGE 408

  Fly   523 AEITEYFDTITYSKGAALVRMLENLVGEEKLRNATTRYLVRHIYSTATTEDYLTAVEEEEGLEFD 587
            .:|...||.|:|.:||.:::|..:...::......:.:|.::.||.|...:...|:..|  |:.|
  Fly   409 KDIMGVFDIISYKRGACVIKMFHHAFRQKLFVRGISHFLEKYRYSVANELNLFDALHSE--LQDD 471

  Fly   588 -----------VKQIMQTWTEQMGLPVVEVEKS--GSTYKLTQKRFLANEDDYAAEAEASSFNYR 639
                       :::||.:||....||::.|.::  .:|...|| |.:..:|:.
  Fly   472 EYFSHQPWASRIREIMLSWTHSEWLPILVVTRNYENNTITFTQ-RSVHMKDEL------------ 523

  Fly   640 WSIPITY--TSSINSE-VQSLIFNHNDNEATITLPE------EASWIKINTNQVGYYRVNYGSEQ 695
            |.|||.:  |.|.|.| .|..:|.....:.|::|.:      ...||.:|....|:|.|.|.::.
  Fly   524 WWIPINFATTQSPNFEDTQVDMFMPPQPQYTVSLEDLNIHVSGRDWIMVNKQHTGFYLVRYDTDN 588

  Fly   696 WAELISALKNSRETFSTADRAHLLNDANTLAAAGQL-NYSVALDLISYLESEQDYVPWSVGTSAL 759
            ...:...|:.:.......:|..|..|...|....:: ...|..:|:.|||.|:|.:.|:.....:
  Fly   589 LMAIARQLQTNHSVIHPINRLGLFRDLGPLIEHNEIEQVEVVFELLKYLELEEDVLTWNQLQDTI 653

  Fly   760 ATLRNRVYYTDLYTNYTTYARKLLTPIVEKVTFTVAADHLENRLRIKVLSSACSLGHESSLQQAV 824
            ..|...::.|...:.:..:.|:|:.|...:|......:..|:.:...:|..|||......|:
  Fly   654 ECLTRNLHGTSSQSLFNEFVRRLVGPTFRRVYVEQGVNLAEDGMFRGILEIACSADLPECLE--- 715

  Fly   825 TLFNQWLASPETRPNPDIRDVVYYYGLQQVNTEAAWDQVWKL---YLDESDAQEKLKLMN----- 881
              :.:.||...      |.|.:|:  ....:..|..|.|..:   ||.:.|.|..:.:|.
  Fly   716 --YTRRLAKEH------IIDKIYF--KDGSDYHAIIDSVLCMGVRYLSDQDFQRIIDMMQEIDRA 770

  Fly   882 ---------CLTAVQVPWLLQRYINWAWDESNVRR-----QDYFTLLGYISTNPVGQSLVWDYVR 932
                     .|...|....|..|:.....|::...     :|...||....:|...:.::|.|:.
  Fly   771 SVYYDDIIYALRCTQSHRHLLYYLEGLMGENSTHMVLSEFEDLMYLLYIYKSNLASRPVIWQYIE 835

  Fly   933 ENWEKL--VDRFGINERTLGRLIPTITARFSTETKLEEMQQFFAKY-PEAGAGTAARQQALEA-- 992
            .|::.|  ...|..:.:.|...:|.     ...:..|.::|..|.: .:.|..|  .|..:|.
  Fly   836 RNYKVLCRAPNFLEHFKQLAGFVPR-----HQRSHFERLRQTIANHMMQEGLNT--NQTLIEVDS 893

  Fly   993 ------VKANIKWLAANKAQVGEWLANYVQQSS 1019
                  :|....:....:.|:.:||.|.:.|::
  Fly   894 PLVGKKMKITENFQDKFEQQIHKWLLNELPQAT 926

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32473	NP_731787.1	Peptidase_M1	143..537	CDD:279741	143/403 (35%)
		M1_APN_2	151..602	CDD:189008	154/471 (33%)
		ERAP1_C	677..992	CDD:288671	66/340 (19%)
CG5849	NP_650979.1	Peptidase_M1	30..423	CDD:279741	143/403 (35%)
		M1_APN_2	38..497	CDD:189008	154/471 (33%)
		ERAP1_C	570..>841	CDD:288671	56/283 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462042
Domainoid	1	1.000	98	1.000	Domainoid score	I364
eggNOG	1	0.900	-	-		E1_COG0308
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X67
	8	7.850