Protein Alignment CG32473 and T12E12.6

DIOPT Version :10

• Sequence 1: NP_731787.1
• Gene: CG32473 / 41636
• FlyBaseID: FBgn0052473
• Length: 1025
• Species: Drosophila melanogaster
• Sequence 2: NP_500831.2
• Gene: T12E12.6 / 188454
• WormBaseID: WBGene00020465
• Length: 641
• Species: Caenorhabditis elegans
• Alignment Length: 630
• Identity: 154/630 - (24%)
• Similarity: 258/630 - (40%)
• Gaps: 113/630 - (17%)

  Fly   145 PKQIKPSKYRLHLR-PDLERKNYSGNI-----------SISLQVLEPIAFIPVHVKQLNVSTVEV 197
            |..|.|..|.|..: |..|...::|::           :|:|..::..:|       .|:|.:..
 Worm    19 PHNIIPLSYDLLFKLPIHEFNGFTGSMVLHFNLSSLSDNITLDAVDLHSF-------RNISLIRS 76

  Fly   198 KRLDESGAPLKDITPTLTFAHPEFEYWVTEFEQPLEAGNYSLLLNFTGSLVDRITGMYQSSYLDK 262
            ..|.|         |||.......|....:||:.|..|.|.|.:   |....||....::.:
 Worm    77 ADLTE---------PTLKSIKILKEKVELKFEKSLFPGQYLLTI---GEYNGRIGNSSEALF--- 126

  Fly   263 LKNRSRSIISTKFEPTYARQAFPCFDEPALKAQFTITVARPSGDEYHVLSNMPVASEYVDGDITE 327
             :.|:..:.:|..:|.:||:.|||.|.||:||.|.:::..|:  :....||......:|:....:
 Worm   127 -ERRNPLLYTTHLQPNHARRLFPCIDHPAVKALFRLSIVHPT--DTVAQSNTIAMDVHVENRKWQ 188

  Fly   328 VTFAETVP-MSTYLAAFVV---SDFQYKETT-------VEGTS--IALKVYAPPAQVEKTQYALD 379
            .|..:..| :..||.||.|   |:.|....|       |.|.|  :.|:|             ||
 Worm   189 RTIFQATPLLPAYLVAFSVMPDSNLQLSRQTSFGVTVRVNGESRGLVLRV-------------LD 240

  Fly   380 TAAGVMAYYINYFNVSYALPKLDLVAIPDFVSGAMENWGLVTFRETALLYDESTSSSVNKQRVAI 444
            .|...........:|...|.|:|.:.:|:: .|.|||||.:|..||       .::|.:...:..
 Worm   241 CALASFEILAGLIDVPLPLNKIDFILVPEY-DGGMENWGHITVSET-------LATSGDDAHLIY 297

  Fly   445 VVAHELAHQWFGNLVTMNWWNDLWLNEGFASFLEYKGVKQMHPEWDMDNQFVIEELHPVLTIDAT 509
            ::|||:||.|.||..|::.||.:.|.|....::..|.||.:..:.....:|.:.:...:..::..
 Worm   298 LIAHEIAHHWIGNRATIDSWNWICLQEDLTDWMALKAVKALLTDEIRLQRFQLAQYVEIQLVEDF 362

  Fly   510 LA-SHPIVKSIESPAEIT-EYFDTITYSKGAALVRMLENLVGEEKLRNATTRYLVRH-IYSTATT 571
            |: .|    |:..|::|. |..:...|.||..|:..||::|||:.:.:.....:..| .|:..|.
 Worm   363 LSPGH----SLYMPSKINQELINRHCYLKGVVLLDTLESVVGEQFMYSVIKSLVGSHSTYNLTTF 423

  Fly   572 EDYLTAVEEEEGLEFDVKQIMQTWTEQMGLPVVEVEKSGSTYKLTQ-KRFLANEDDYAAEAEASS 635
            ..|...:..:...  .|.||.:.|....|.|.:.||.:|.:.:|.| .|.|
 Worm   424 TSYFDQIRVDRNA--TVGQIYEYWYTTGGYPSILVENNGPSSRLQQLSRPL-------------- 472

  Fly   636 FNYRWSIPITYTSSINSEVQSLIFNHNDNEATITLPEEASWIKINTNQVGYYRVNYGSEQWAELI 700
                |.:.:|.|.:|    ...:|:.     :|....|.:.:.:|.|...:.||||.|..|..:.
 Worm   473 ----WPLKMTSTLAI----PQFVFSE-----SIVFASENAPLLVNLNFTSFMRVNYDSLTWTAIF 524

  Fly   701 SALKNSRETFSTADRAHLLND-----ANTLAAAGQLNYSVALDLI 740
            ..:....|.||...||.|::|     ||.....|.:.....:|::
 Worm   525 KYMFEEPELFSAVGRAQLVSDFCYFYANDKVDNGTILKEAVVDMV 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32473	NP_731787.1	M1_APN-Q_like	151..597	CDD:341064	116/473 (25%)
		ERAP1_C	676..995	CDD:463368	19/70 (27%)
T12E12.6	NP_500831.2	GluZincin	25..402	CDD:472708	107/426 (25%)