Protein Alignment CG32473 and AC3.5

DIOPT Version :10

• Sequence 1: NP_731787.1
• Gene: CG32473 / 41636
• FlyBaseID: FBgn0052473
• Length: 1025
• Species: Drosophila melanogaster
• Sequence 2: NP_001256214.1
• Gene: AC3.5 / 179447
• WormBaseID: WBGene00007071
• Length: 1090
• Species: Caenorhabditis elegans
• Alignment Length: 1068
• Identity: 248/1068 - (23%)
• Similarity: 449/1068 - (42%)
• Gaps: 167/1068 - (15%)

  Fly    39 AAFCVFLLVLCGFLLGALVYVGKNIAEEHQRQ---QHANASQWALNSTIRTVYVDRDQLLSTKPI 100
            :|.|:|||.:...:..|  ::|..:.:::...   :.||.|.....:..|:....:|       |
 Worm    79 SAICLFLLAVAAIIFAA--FLGHYLTKQNYEMMQFKSANESMTTCKNFTRSHKKHQD-------I 134

  Fly   101 ISVLSDNRFYTTQVPTSKKSSIMATVAPAVKAASKVLQNLGFRLPKQIKPSKYRLHLRPDLERKN 165
            ::....:...:.:.||.::                      ..|||.::|..|.:.|.|.:....
 Worm   135 VNEEDADENASIKQPTKEE----------------------LALPKNVQPVWYDVSLSPKVGGNG 177

  Fly   166 YSGNISISLQVLEPIAFIPVHVKQLNVS------------TVEVKRLDESG-------------- 204
            ..|...:.|.:.||...|.::.|.:..:            |...|:..:||
 Worm   178 TMGLAHVKLNIEEPTNKIVLNAKDIEFTRNLEKIQLSKEVTKRAKKSVDSGTNSTSEMPEGSGEE 242

  Fly   205 --------APLKDITPTLTFAHPEFEYWVTEFEQPLE------------AGNYSLLLNFTGSLVD 249
                    ...:..||..:|.....:....||::.||            .....|.:.|| |.|.
 Worm   243 AMATTATTTTTESTTPVSSFVDTGIKVTNIEFDENLEKVTLTLDQELKKGSTVVLKIPFT-SKVS 306

  Fly   250 RITGMYQSSYLDKLKNRSRSIISTKFEPTYARQAFPCFDEPALKAQFTITVARPSGDEYHVLSNM 314
            ...|:.:..|.:. :.:.:|:.:|:...:|.|..||.||:.|.||...||:....|.  .|::|.
 Worm   307 NNNGLKEYKYKNS-EGKEQSMFTTQPSYSYLRHVFPSFDQEAFKAPAAITLMHSKGS--IVVANT 368

  Fly   315 PVASEYVDGDITEVTFAETVPMSTYL-AAFVVSDFQYKE-TTVEGTSIALKVYAPPAQVEKTQYA 377
            .|.:: .|||      |:|..::..| ..||:.|....| .|..|  |.::::..|.....|:.:
 Worm   369 GVKTK-DDGD------AQTSTLNKVLDPDFVIGDLVASEVNTTSG--ITIRIWTRPEVKHSTEQS 424

  Fly   378 LDTAAGVMAYYINYFNVSYALPKLDLVAIPDFVSGAMENWGLVTFRETALLYDESTSSSVNKQRV 442
            ||.|...:....:..........||:||:|.|.:|...:...:...|..:||:|.::....|.|:
 Worm   425 LDYANQAIDAMEHILQSRLESKSLDIVAVPGFQTGNRVSPSFIVLPEEDILYNEQSNDINQKTRI 489

  Fly   443 AIVVAHELAHQWFGNLVTMNWWNDLWLNEGFASFLEYKGVKQMHPEWDMDNQFV-IEELHPVLTI 506
            |.::::.:|.||||.:.....:...||||....|||.:.::::   .|:::..: ..|:..:|..
 Worm   490 ARMISNRIAAQWFGGITNPEEFGTFWLNEALPRFLEVEALEKI---LDINSDDLWTYEMEKILER 551

  Fly   507 DATLASHPI-VKSIESPAEITEYFDTITYSKGAALVRMLENLVGEEKLRNATTRYLVRHIYSTAT 570
            |||..|.|: ||::.|.|:|.|........||||::||::..||......|     :|...|:
 Worm   552 DATATSQPLRVKNVFSSADIAEIDHEFIGKKGAAVLRMIQKSVGVNVFNKA-----IRSFVSS-- 609

  Fly   571 TEDYLTAVEEEEGL------------------EFDVKQIMQTWTEQMGLPVVEVEK-SGSTYKLT 616
               |.:|...::||                  ..||.:.:.||.:|:|.|:|.||| ...|.:|:
 Worm   610 ---YRSAYPYDDGLWKSFEKALGGKLKGWNNEPLDVAKFVNTWVDQIGFPLVSVEKLDDETVELS 671

  Fly   617 QKRFLANEDDYAAEAEASSFN----YRWSIPITYTSSINSEVQSLIFNHNDNEATITLPEEAS-W 676
            |:||   ::|:..:.:....|    :.|.:|:...||  ..|.::.:.|.    ...||...| .
 Worm   672 QERF---KNDHKTKEQFKFRNAKYWFNWEVPLFLKSS--GPVGNVSWLHE----AFRLPLNTSDS 727

  Fly   677 IKINTNQVGYYRVNYGSEQWAELISALKNSRETFSTADRAHLLNDANTLAAAGQLNYSVALDLIS 741
            |.:||:..|.|||||..::|.::...|:.|....|...||.|::|...||.:|.|.:..||::.|
 Worm   728 IYLNTDSNGVYRVNYEEKRWNDIAKQLEKSHGKLSERTRARLISDVFALANSGALPFETALNVTS 792

  Fly   742 YLESEQDYVPWSVGTSALATLRNRVYYTDLYTNYTTYARKLLTPIVEKVTFT---VAADHLENRL 803
            ||..|...|||.:.|.....|..|:....:.....::..:.:....|:::.:   .::::|:|||
 Worm   793 YLPMETATVPWLIATRIFKKLTERLEGAPIQDKLNSFIYQKIHKKFEEISSSPGEASSNYLKNRL 857

  Fly   804 RIKVLSSACSLGHESSLQQAVTLFNQWLASP---------ETRPNP-DIRDVVYYYGLQQVNTEA 858
            ...:|.....:..|.|.::...||.:...:|         :....| |:|:.||..|::..| :.
 Worm   858 YANLLDLMAIVKPEKSNEKLNELFVEGFLAPCQFSGNFSSDCSEVPGDLREKVYCNGVEFGN-DT 921

  Fly   859 AWDQVWKLYLDESDAQEKLKLMNCLTAVQVPWLLQRYINWAWDESNVRRQDYFT-LLGYISTNPV 922
            .::.|.:|...|.|..||..|.|.|...:.|..|:|.|     ..|:......| ||..:::.||
 Worm   922 VFETVRELAEKEVDGAEKDLLQNSLACFRDPRALRRLI-----LDNLNSTSTVTLLLRKMNSRPV 981

  Fly   923 GQSLVWDYVRENWEKLVDRFGINERTLGRLIPTITARFSTETKLEEMQQFFAKYPEAGAGTAARQ 987
            |:.:..:::.:||..::.:...|:......|.........|.:...::.|...:.::..|..:..
 Worm   982 GKEIATNWIIDNWSTVLKKKFKNDPETLNAIADAGIILDNEREKSMIETFMEHHHKSTHGIESLD 1046

  Fly   988 QALEAVKANIKWLAANKAQVGEWLANYV 1015
            :.:|....:|.|   .|.::.| |.:|:
 Worm  1047 KKIEEATTDIYW---RKQKINE-LNDYL 1070

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32473	NP_731787.1	M1_APN-Q_like	151..597	CDD:341064	121/513 (24%)
		ERAP1_C	676..995	CDD:463368	79/332 (24%)
AC3.5	NP_001256214.1	GluZincin	165..651	CDD:472708	121/511 (24%)
		beta-trefoil_FSCN-like	<685..741	CDD:483951	16/61 (26%)
		ERAP1_C	728..1056	CDD:463368	79/333 (24%)