Protein Alignment CG32473 and Y67D8C.9

DIOPT Version :9

• Sequence 1: NP_731787.1
• Gene: CG32473 / 41636
• FlyBaseID: FBgn0052473
• Length: 1025
• Species: Drosophila melanogaster
• Sequence 2: NP_001122826.1
• Gene: Y67D8C.9 / 177088
• WormBaseID: WBGene00022073
• Length: 1144
• Species: Caenorhabditis elegans
• Alignment Length: 1159
• Identity: 276/1159 - (23%)
• Similarity: 446/1159 - (38%)
• Gaps: 271/1159 - (23%)

  Fly     7 VRPRSSLSTDDNHRIKDTNRPHKARSNTILTLAAFCVFLLVLCGFLLGALVYVGKNIAEEHQRQQ 71
            :|..|..:...:.|.:...|........|..:....:|||.    :|.||: :|..|:||:|:.
 Worm    18 IRNGSGAAATVHFRQESRRRKSDFARKCIAVILLHAIFLLA----ILAALI-IGHWISEENQKL- 76

  Fly    72 HANASQWALNSTIRTVYV-----------------DRDQLLSTKPIISVLSDNRFYTTQ------ 113
               :::..||.|:...|:                 ....||:|..  :.|..::..|..
 Worm    77 ---SNRTMLNITLAEAYLLEGIYTTSTATPESLSHHHTHLLTTSS--AALGQSKKKTPPRVVERL 136

  Fly   114 VPTSKKSSI-MATVAP--------------AVKAASKVLQNLGFRLPKQIKPSKYRLHLRPDLER 163
            :|..||.:. ::.|.|              ||:|.......|...||..|.|..|.|    .|:.
 Worm   137 IPLEKKRNFTISDVFPPPADGGFGIAEQLHAVRANKLSTDALLVPLPLYILPYHYDL----QLDF 197

  Fly   164 KNYSGNISISLQVLEPIAFIPVHVKQLNVST-------------VEVKRLDESGAPLKDITPTLT 215
            ..:..::.|.       |.|.:|::....||             :|..||.:.|....    ..|
 Worm   198 SQFDTHLFIR-------ANISIHLESYGNSTEDEIQFHLGPNIKMERMRLRKDGKKFY----AKT 251

  Fly   216 FAHPEF-EYWVTEFEQPLEAGNYSLLLNFTGSLVDR-ITGMYQSSYLDKLKNRSRSIIS--TKFE 276
            |...|. :........||:.|.|.|.:.:..::.|. :.|:..|  ||...|.|....|  ||||
 Worm   252 FKREESKKLGRISLRDPLQKGKYILEMTYNMTICDEDVDGVRCS--LDNQTNSSLKATSFTTKFE 314

  Fly   277 PTYARQAFPCFDEPALKAQFTITVARPSGDEYHVLSNMPVASEY----VDGDITEVTFAETVPMS 337
            ||.||..|||:|||.:||.|.|:|..  ..:|.||||||....:    .:.......|..|.|||
 Worm   315 PTLARAFFPCWDEPGVKATFNISVRH--NKKYTVLSNMPPVESHDHKSWEDQFKTTVFQTTPPMS 377

  Fly   338 TYLAAFVVSDFQYKETTVEGTSIALKVYAPPAQVEKTQYALDTAAGVMAYYINYFNVSYALPKLD 402
            |||.||.:.:|...|:..| ..|.:.|:..|..|...::.|:.|..:.....:...:.|.|||:|
 Worm   378 TYLLAFAIGEFVKLESRTE-RGIPVTVWTYPEDVMSMKFTLEYAPVIFDRLEDALEIPYPLPKVD 441

  Fly   403 LVAIPDFVSGAMENWGLVTFRETALLY--------DESTSSSVNKQRVAIVVAHELAHQWFGNLV 459
            |:|..:|..|.|||||||.|...::.|        :|:.....|:.|:..::|||.|||||||||
 Worm   442 LIAARNFHVGGMENWGLVVFEFASIAYTPPITDHVNETVDRMYNEFRIGKLIAHEAAHQWFGNLV 506

  Fly   460 TMNWWNDLWLNEGFASFLEYKGVKQMHPEWDMDNQFVIEELHPVLTIDATLASH--PIVKSIESP 522
            ||..|::|:||||||:|..|   :.|..|..:..||...:....|.:..:...|  .:|:.:.:.
 Worm   507 TMRDWSELFLNEGFATFYVY---EMMSTERPVTAQFEYYDSLASLILAQSEEDHRLSLVRELATE 568

  Fly   523 AEI-TEYFDTITYSKGAALVRMLENLVGEEKLRNATTRYLVRHIYSTATTEDYLTAVE--EEEGL 584
            ::: :.:..|..|:||..|:|||.:||.:...:.|..|||.::.|.:.:.:|...::.  .:.|.
 Worm   569 SQVESSFHPTNLYTKGCVLIRMLRDLVSDFDFKAAVRRYLRKNAYRSVSRDDLFASLPAYADHGA 633

  Fly   585 EFD-VKQIMQTWTEQMGLPVVEVEKSGSTYKLT--QKRFLANE-DDYAAEAEAS-SFNYR----- 639
            |.: :..:::.|....|:|.:.:.::.....:|  |::.:.:| ..:..:.:|| |..||
 Worm   634 EQEKLSHVLEGWFVNEGIPEITLIRNYDNEMMTISQRKTVHHEYRSFLKDRKASASVRYRGSRSA 698

  Fly   640 ------------------------------------------------------------WSIPI 644
                                                                        |:|||
 Worm   699 EDGSTLFDDALFDGYIEKKKDRRRKHRPIRRKTSTPPSISPISRRDELRKPRRVGASQDLWTIPI 763

  Fly   645 TYT--SSINSEVQSL--------IFNHNDNEATITLPEEASWIKINTNQVGYYRVNYGSEQWAEL 699
            ||.  |...||.|.:        ..:..|.|.:   |.:|  :.:|......|||||....|..|
 Worm   764 TYMFGSLKTSEGQVIREFWLKNRTVSFGDAEIS---PNQA--VLVNPEWKYPYRVNYDLLNWKLL 823

  Fly   700 ISALKNSRETFSTADRAHLLNDANTLAAAGQLNYSVALDLISYLESEQDYVPWSVGTSALATLRN 764
            ...|..:....:...|..|:.||... .:..:|..:.|.|:.||..|........|..|
 Worm   824 ARTLHQNHLEINEKSRMQLILDAEYF-LSNSVNPHLYLYLLGYLAHETKMEVMLFGIDA------ 881

  Fly   765 RVY-YTDLYTNYTTYARKLL----TPIVEKVTFTVAADHLENRLRI----------------KVL 808
             || :.|:|.  .|...|.:    .|::.::      |||.|..::                |:.
 Worm   882 -VYKFIDVYK--ATQLNKAILVYFEPVISQM------DHLLNESQVDAETASLWLVRPERLAKLY 937

  Fly   809 SSACSLGHESSLQQAVTLFNQWLASPETRPNPDIRDVVYYYGLQQVNTEAAWDQVWKLYLDESDA 873
            ...|:.|..|......|  .:|..||: ....|:.        :||.  |...|::....||...
 Worm   938 QMRCAAGLSSCKNDYYT--QRWSRSPD-EWTEDVH--------KQVT--AVCHQLFTNTPDEVKT 989

  Fly   874 QEKLKLMNCLTAVQVPWLLQ-RYINWAWDESNVRRQDYFTLLGYIST------------------ 919
            .:.| |.:.|.:....|.|. :....:.|:..:||    |....:||
 Worm   990 VQDL-LDSRLQSSGAKWALTVQLAACSHDQKLLRR----TARAIVSTKNAVVYASALQSDFSLHY 1049

  Fly   920 NPVGQSLVWDYVRE--NWEKLVDRFGINERTLGRLIPTITARFSTETKLEEMQQ 971
            ||..:..:|..:.:  .:||.. .|..|...   ::|.......:...::|:||
 Worm  1050 NPTFRKYLWAEIAKMSTFEKTA-LFSTNSTD---ILPASRILLHSVKTIDELQQ 1099

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32473	NP_731787.1	Peptidase_M1	143..537	CDD:279741	132/425 (31%)
		M1_APN_2	151..602	CDD:189008	146/485 (30%)
		ERAP1_C	677..992	CDD:288671	69/337 (20%)
Y67D8C.9	NP_001122826.1	Peptidase_M1	182..584	CDD:279741	132/424 (31%)
		M1_APN_2	190..652	CDD:189008	146/484 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020