Protein Alignment CG32473 and trhde

DIOPT Version :10

• Sequence 1: NP_731787.1
• Gene: CG32473 / 41636
• FlyBaseID: FBgn0052473
• Length: 1025
• Species: Drosophila melanogaster
• Sequence 2: XP_002939988.3
• Gene: trhde / 100489066
• XenbaseID: XB-GENE-1013649
• Length: 1020
• Species: Xenopus tropicalis
• Alignment Length: 1011
• Identity: 315/1011 - (31%)
• Similarity: 518/1011 - (51%)
• Gaps: 68/1011 - (6%)

  Fly    63 IAEEHQRQQHANASQWALNSTIRTVYVDRDQLLSTK---------------PIISVLSDNRFY-- 110
            |.:...|.......|||....:||...:|...:..|               .||:||...||.
 Frog    20 IEDTGMRNGRGLQDQWADTVAVRTRTTERQITVHRKLVLAFAISILALIVVTIIAVLLSVRFEEC 84

  Fly   111 ---TTQVPTSK--------------KSSIMATVAPAVKAASKVLQNLGF-RLPKQIKPSKYRLHL 157
               :|:|..|.              |.|...|..|.||...:..:...: |||..::|..|.|.:
 Frog    85 TDGSTRVINSSILEAARFNQNLELDKDSGEGTQRPPVKDPEEEWKPWTYLRLPTHLRPLHYNLMV 149

  Fly   158 RPDLERKNYSGNISISLQVLEPIAFIPVHVKQLNVSTVEVKRLDESGAPLKDITPTLTFAHPEFE 222
            ...:....:.|.:::.::.|....:|.||..:|.|..|:|.....:|    ::..:..|.:|:.:
 Frog   150 TAFMNNFTFCGEVNVEIECLNSSRYIVVHAHRLTVERVQVAEDRVAG----EVKVSHYFPYPQNQ 210

  Fly   223 YWVTEFEQPLEA-GNYSLLLNFTGSLVDRITGMYQSSYLDKLKNRSRSIISTKFEPTYARQAFPC 286
            ..|....:.||| .:|:|.:.::..:.:.:.|.::|||:  |....||:..|:|.|.:||:||||
 Frog   211 VLVVVLNRSLEAQKSYNLKIIYSAIIENELLGFFRSSYV--LHGERRSLAVTQFSPIHARKAFPC 273

  Fly   287 FDEPALKAQFTITVARPSGDEYHVLSNMPV-ASEYVDGDITEVTFAETVPMSTYLAAFVVSDFQY 350
            ||||..||.|.|::...:  .|..|||||| .|.:.:|......|::|..||||..|:.|.:|.:
 Frog   274 FDEPIYKATFKISIRHQT--SYLSLSNMPVETSVFEEGGWVTDHFSQTPLMSTYYLAWAVCNFTF 336

  Fly   351 KETTVEGTSIALKVYAPPAQVEK--TQYALDTAAGVMAYYINYFNVSYALPKLDLVAIPDFVSGA 413
            ||...: :.:.:::||.|..:.:  ..|||:....::.:|.:||.|.|:||||||:|:|.....|
 Frog   337 KEAVTQ-SGVVVRLYARPDAIRRGSGDYALNITKRLLEFYEDYFRVPYSLPKLDLLAVPKHPYAA 400

  Fly   414 MENWGLVTFRETALLYDESTSSSVNKQRVAIVVAHELAHQWFGNLVTMNWWNDLWLNEGFASFLE 478
            ||||||..|.|..:|.|.|.||......|.:|:.||:.|||||:|||..||.|:||.||.|.:.|
 Frog   401 MENWGLSVFVEQRILLDPSISSISYLLDVTMVIVHEICHQWFGDLVTPIWWEDVWLKEGLAHYFE 465

  Fly   479 YKGVKQMHPEWDMDNQ-FVIEELHPVLTIDATLASHPIVKSIESPAEITEYFDTITYSKGAALVR 542
            :.|...::|.|:|:.| |:.:.||.|:.:|...:|||:.:.:....:|...||.|.|.|||||:|
 Frog   466 FVGTDYLYPGWNMEKQRFLTDVLHEVMLLDGLASSHPVSQEVLKATDIDRVFDWIAYKKGAALIR 530

  Fly   543 MLENLVGEEKLRNATTRYLVRHIYSTATTEDY---LTAVEEEEGLEFDVKQIMQTWTEQMGLPVV 604
            ||.|.:|.:..:.....||..|.|..|...|.   ||.|.:.||...:::::|..||.|||.||:
 Frog   531 MLANFMGHKVFQRGLQDYLTTHKYGNAARNDLWNTLTKVLKNEGKLLNIREVMDQWTLQMGYPVI 595

  Fly   605 EVEKSGST---YKLTQKRFLANEDDYAAEAEASSFNYRWSIPITYTSSINSEV--QSLIFNHNDN 664
            .:.::.:|   ..:||:.||.|.|....:.|..:.:..|.||:|......|.:  |::|:..|.:
 Frog   596 TILRNDTTDDIITITQEHFLYNIDKRTRDKEFRNKSSLWQIPLTIAVGNTSHISPQAIIWVSNKS 660

  Fly   665 E-ATITLPEEASWIKINTNQVGYYRVNYGSEQWAELISALKNSRETFSTADRAHLLNDANTLAAA 728
            | ..|...:|::|:..|.:|:||:||||....|..|...|..:.|..|.::||.|::||..||.|
 Frog   661 EYHRIPSLDESNWVLGNLDQIGYFRVNYDVRNWRLLTDQLMRNSEVISVSNRAALIDDAFNLARA 725

  Fly   729 GQLNYSVALDLISYLESEQDYVPWSVGTSALATLRNRVYYTDLYTNYTTYARKLLTPIVEKVTF- 792
            |.|..::.|::|.||..|:|::||...:.||..|...:..|:.|:.::.|..|.::.:..::.:
 Frog   726 GYLTQNIPLEIIRYLSEEKDFLPWHAASRALYPLDKLLDRTEDYSIFSEYILKQVSTMYFRLGWP 790

  Fly   793 -------TVAADHLENRLRIKVLSSACSLGHESSLQQAVTLFNQWLASPETRPNPDIRDVVYYYG 850
                   .|...:....||.:|:..|||.|::...|:|.|:.:.|::|...|..|::||:||..|
 Frog   791 TNGQNGSAVPTSYQTEELRREVIMLACSFGNKQCHQKAATMISDWISSNRNRIPPNVRDIVYCTG 855

  Fly   851 LQQVNTEAAWDQVWKLYLDESDAQEKLKLMNCLTAVQVPWLLQRYINWAWDESNVRRQDYFTLLG 915
            :..:: |..|:.:|..:...:...||..|:..||......||.|.:|.:.:...|..||...::.
 Frog   856 VSLMD-EDVWEFIWMKFHSSTAVSEKKILLEALTCSDNRNLLNRLLNLSLNSEVVLDQDAIDVII 919

  Fly   916 YISTNPVGQSLVWDYVRENWEKLVDRFGINERTLGRLIPTITARFSTETKLEEMQQFFAKYPEAG 980
            :::.||.|:.|.|.:.|:.|:.|..|:|.......:||..:|...:||.:|.|::.|..:: :.|
 Frog   920 HVARNPHGRDLAWKFFRDKWKILNARYGEALFMNSKLISGVTEFLNTEEELNELKDFIQQH-KGG 983

  Fly   981 AGTAARQQALEAVKANIKWLAANKAQVGEWLANYVQ 1016
            :..|:..:|.|.|.||::|....:.::.:||...|:
 Frog   984 SAVASLSRATETVDANVRWQHLYRDELFQWLRKTVK 1019

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32473	NP_731787.1	M1_APN-Q_like	151..597	CDD:341064	159/453 (35%)
		ERAP1_C	676..995	CDD:463368	97/326 (30%)
trhde	XP_002939988.3	M1_APN-Q_like	143..588	CDD:341064	159/453 (35%)
		ERAP1_C	673..998	CDD:463368	97/326 (30%)