Protein Alignment CG8774 and pepN

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_415452.1
• Gene: pepN / 947253
• ECOCYCID: EG10696
• Length: 870
• Species: Escherichia coli
• Alignment Length: 906
• Identity: 197/906 - (21%)
• Similarity: 335/906 - (36%)
• Gaps: 223/906 - (24%)

  Fly    65 DYRLPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYL----------LDITSV 119
            |||.|...: |..:|.:..|.:.           .||.|.:|.:.|...          |.:.||
E. coli    12 DYRAPDYQI-TDIDLTFDLDAQK-----------TVVTAVSQAVRHGASDAPLRLNGEDLKLVSV 64

  Fly   120 YVLNREVEKFELEEERQFLIITLTEELAVDASITLGII--FGGQMKDKLVGLYSSTYLNEAGATR 182
            :: |.|......|||...:|..|.|.      .||.||  ........|.|||.|   .:|..|:
E. coli    65 HI-NDEPWTAWKEEEGALVISNLPER------FTLKIINEISPAANTALEGLYQS---GDALCTQ 119

  Fly   183 TISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSY-HAVSNMQQTESNYLGDYTEAI-FET 245
            ..:......||      ..|.|.:.|.|...::.....| ..:||..:.....|.:....: ::.
E. coli   120 CEAEGFRHITY------YLDRPDVLARFTTKIIADKIKYPFLLSNGNRVAQGELENGRHWVQWQD 178

  Fly   246 SVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYK 310
            ......||..::..||.....|..... |.:.:::.|.....:::..:|:...:...::..:.:.
E. coli   179 PFPKPCYLFALVAGDFDVLRDTFTTRS-GREVALELYVDRGNLDRAPWAMTSLKNSMKWDEERFG 242

  Fly   311 VPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNL 375
            :.|.|....:.|:..|..||||:.||..:....:|.....::..:...|...:.||..|.|.||.
E. coli   243 LEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNR 307

  Fly   376 VTMKWWNDLWLNEG--------FARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPI 432
            ||.:.|..|.|.||        |:..:..:.||.::....|.      .||  ...||...:|||
E. coli   308 VTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRINNVRTMR------GLQ--FAEDASPMAHPI 364

  Fly   433 VQKVESPD---EITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTE 494
                 .||   |:...:....||||..||||:.||:|.|.|::.:..|..:|..:....|||:..
E. coli   365 -----RPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGMQLYFERHDGSAATCDDFVQA 424

  Fly   495 VEAVVTDLDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLS----NPASYEEAPSDSAYGY 555
            :|. .:::|:.... .|..|.|.|::.|.   |.....|:|..|:    .||:.::|.....:
E. coli   425 MED-ASNVDLSHFR-RWYSQSGTPIVTVK---DDYNPETEQYTLTISQRTPATPDQAEKQPLH-- 482

  Fly   556 KWSVP--ITWFADDG--------------------SENSFIYD----YDVDSV----GIAVPSEV 590
               :|  |..:.::|                    :|.:|::|    ..|.::    ...|..|.
E. coli   483 ---IPFAIELYDNEGKVIPLQKGGHPVNSVLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEY 544

  Fly   591 QW-----------------------------IKLNV--NQTG------------YYRVNYEESLW 612
            :|                             |||||  :|.|            :..|..:|.:.
E. coli   545 KWSDQQLTFLMRHARNDFSRWDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKID 609

  Fly   613 ALLIQQLTTSPARFEIADRGHLLNDAFALADANQ-----LSYKIPLDMTA---------YLAQER 663
            ..|..::.|.|:..|:|:...:: |..|:|:..:     |:.::..::.|         |..:..
E. coli   610 PALAAEILTLPSVNEMAELFDII-DPIAIAEVREALTRTLATELADELLAIYNANYQSEYRVEHE 673

  Fly   664 DFVPWYVASNKLR-SLHRSLMFSEGYVSYLTYARSLIAGVYEEVGWTVDADNHLKNRLRVSILTA 727
            |     :|...|| :..|.|.|.|.::     |..|::..:.|.....||         ::.|:|
E. coli   674 D-----IAKRTLRNACLRFLAFGETHL-----ADVLVSKQFHEANNMTDA---------LAALSA 719

  Fly   728 ACALGVP--DCLQQASERFSTFLEN----------PTTRPSPDLREIVYYYGMQQSTSQSSWDQL 780
            |.|..:|  |.|.|  |....:.:|          ..|.|:.::.|.|......:|.:.|:.:::
E. coli   720 AVAAQLPCRDALMQ--EYDDKWHQNGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRI 782

  Fly   781 FQL-----------FVAETDASEKLKLMYGLSGV--RNSQYLFDFLAQASSDESIVRSQDY 828
            ..|           |.|| |.|..|.|:..|:.:  ||.|.....:      |.::|.:.|
E. coli   783 RSLIGAFAGSNPAAFHAE-DGSGYLFLVEMLTDLNSRNPQVASRLI------EPLIRLKRY 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	108/462 (23%)
		ERAP1_C	592..912	CDD:463368	65/320 (20%)
pepN	NP_415452.1	pepN	1..870	CDD:237585	197/906 (22%)