Protein Alignment CG8774 and Rnpep

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_112359.2
• Gene: Rnpep / 81761
• RGDID: 621137
• Length: 650
• Species: Rattus norvegicus
• Alignment Length: 532
• Identity: 125/532 - (23%)
• Similarity: 205/532 - (38%)
• Gaps: 113/532 - (21%)

  Fly   178 AGATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESNYLGDYTEAI 242
            ||..:....|:.:....|..|||||.||:|.|::..|..|.| :.||.:....|......:   .
  Rat   159 AGKKKPFVYTQGQAVLNRAFFPCFDTPAVKCTYSALVEVPDG-FTAVMSASTWERRGPNKF---F 219

  Fly   243 FETSVSMSTYLVCIIVSDFAS----------------QSTTVKANGIGEDFSMQAYATSHQINKV 291
            |:.:..:.:||:.:.:.|.||                ::...:.||:.|:|    .||..::
  Rat   220 FQMNQPIPSYLIALAIGDLASAEVGPRSRVWAEPCLIEAAKEEYNGVIEEF----LATGEKL--- 277

  Fly   292 EFALEFGQAVTEYYIQYYKVPYPLTKLDMAAI-PDFASGAMEHWGLVTYRETALLYDPSYSSTAN 355
                 ||             ||...:.|:..: |.|..|.||: ..:|:....||        |.
  Rat   278 -----FG-------------PYVWGRYDLLFMPPSFPFGGMEN-PCLTFVTPCLL--------AG 315

  Fly   356 KQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQ-----------YKGVNAVHPDWGML 409
            .:|:|..:.|||:|.|||||||...|.:.||||||..|.|           |..:.|. ....:|
  Rat   316 DRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAA-TGRALL 379

  Fly   410 EQFQIVALQPVLLYDAKLSSHPIVQKVESPDEITAIFDTISYEKGGSVIRMLETLVG-AEKFEEA 473
            .|...|:.:...|...::...|.|    .||:   .::...||||...:..|..||| .|:|::.
  Rat   380 RQHMDVSGEENPLNKLRVKIEPGV----DPDD---TYNETPYEKGYCFVSYLAHLVGDQEQFDKF 437

  Fly   474 VTNYLVKHQFNNTVTDDFLTEVEAVVTDLDIKKL-------MLTWTEQMGY-PVLNVSKVADGSF 530
            :..|:.:.:|.:.:.:|||........:|..|.:       ...|....|: |.|......|...
  Rat   438 LKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFNRWLNTPGWPPYLPDLSPGDSLM 502

  Fly   531 KVTQQRFLSNPASYEEAPSDSAYGYK-W-SVPITWFADDGSENSFIYDYDVDSVGIAVPSEVQWI 593
            |..::......||..:..:..|.... | :..:.:|.|...:.|.:...:|..:|...|
  Rat   503 KPAEELAELWAASEPDMQAIEAVAISTWKTYQLVYFLDKILQKSPLPPGNVKKLGETYP------ 561

  Fly   594 KLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPL----- 653
            |::..|....|:.     |..:|.:.......:::.|        |..:...| .|.:||
  Rat   562 KISNAQNAELRLR-----WGQIILKNDHQEEFWKVKD--------FLQSQGKQ-KYTLPLYHAMM 612

  Fly   654 ---DMTAYLAQE 662
               :|...||:|
  Rat   613 GGSEMARTLAKE 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	95/370 (26%)
		ERAP1_C	592..912	CDD:463368	15/79 (19%)
Rnpep	NP_112359.2	M1_LTA4H	24..484	CDD:341062	95/370 (26%)
		Leuk-A4-hydro_C	530..645	CDD:462686	22/115 (19%)