Protein Alignment CG8774 and Aopep

DIOPT Version :9

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_001276853.1
• Gene: Aopep / 72061
• MGIID: 1919311
• Length: 823
• Species: Mus musculus
• Alignment Length: 547
• Identity: 106/547 - (19%)
• Similarity: 186/547 - (34%)
• Gaps: 163/547 - (29%)

  Fly   187 TKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESNYLGD-YTEAIFETSVSMS 250
            |...|...|..|||.:.|...:|:..||...:.....:|.....:...|.: |....:..::.|.
Mouse   271 TMGSPINNRALFPCQEPPVAMSTWQATVRAAASFVVLMSGENSAKPTPLREGYMSWHYYVTMPMP 335

  Fly   251 TYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQI---------------NKVEFALEF--G 298
            .....|.|..:    |.:|......|..|    |.|.:               |.:|:...|  .
Mouse   336 ASTFAIAVGCW----TEMKPKASPPDDLM----TEHSLPLSPSEADLRYDNTCNHMEYPCRFQSA 392

  Fly   299 QAVTEYYIQY-----------------YKVP------------YPLTKLDMAAIP-DFASGAMEH 333
            .|.::..|.|                 :.:|            :|.::||:..:| :|.|..|..
Mouse   393 SAASQDIIPYRVFAPVCLEGACQEALLWLIPSCLSAAHSVLGTHPFSRLDILIVPTNFPSLGMAS 457

  Fly   334 WGLVTYRETALLYDPSYSSTANKQSIAGT-LAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQ-- 395
            ..::..         |.|:......:.|| |.|||||.|||..:..:.|.:.||:||||.:::
Mouse   458 PHIIFL---------SQSTLTGTSHLCGTRLCHEIAHSWFGLAIGARDWTEEWLSEGFATHLEDI 513

  Fly   396 -YKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPDE-----ITAI--------- 445
             :.....:.|...:.:|.....|:...|.| :|.:.|...:|..|::     ::|.
Mouse   514 FWAEAQQLPPHEALEQQELRACLRWHRLQD-ELRNSPEGMQVLRPNKEETGHVSASGASVVKHGL 577

  Fly   446 -----FDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNN--TVTDDFLTEVEAVVTD-- 501
                 |..:.|.||..::|.|...:|.:.:...:..::  |.|:.  .::.|||..:...:.:
Mouse   578 NPEKGFMQVHYLKGYFLLRFLTRTLGEKIYFPFLRKFV--HLFHGQLILSQDFLQMLLENIPENK 640

  Fly   502 ---LDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPITW 563
               |.::.::..|.|..|.|                      .|..||..::
Mouse   641 RLGLSVENIVRDWLECSGIP----------------------KALQEERKAE------------- 670

  Fly   564 FADDGSENSFIYDYDVDSVGIAVPSEV-QWIKLN----VNQTGYYRVNYEE-------SLWALLI 616
                        |.....:...|.||| :||::|    ..:.|...|.:|:       .|...|:
Mouse   671 ------------DCSPSRLARQVGSEVAKWIRVNRRPRKRKRGKREVAFEKLSPDQIVLLLEWLL 723

  Fly   617 QQLTTSPARFEIADRGHLLNDAFALAD 643
            :|.|.||...      |.|...:.|.:
Mouse   724 EQKTLSPQTL------HCLQQTYHLPE 744

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	Peptidase_M1	67..454	CDD:279741	68/337 (20%)
		M1_APN_2	75..518	CDD:189008	82/408 (20%)
		ERAP1_C	593..910	CDD:288671	14/62 (23%)
Aopep	NP_001276853.1	GluZincin	186..634	CDD:301352	78/382 (20%)
		Leuk-A4-hydro_C	680..821	CDD:286244	19/71 (27%)
		Nucleolar localization signal. /evidence=ECO:0000269|PubMed:17803194	693..703		1/9 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810