Protein Alignment CG8774 and LOC5667739

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_001689317.3
• Gene: LOC5667739 / 5667739
• VectorBaseID: AGAMI1_012453
• Length: 957
• Species: Anopheles gambiae
• Alignment Length: 983
• Identity: 270/983 - (27%)
• Similarity: 449/983 - (45%)
• Gaps: 116/983 - (11%)

  Fly     9 QVVLSWAVVAFATATVVVAVQKA------------QLERDLRDVQDKIDVFEEWSGESRTRMKRE 61
            :.||..|::....:....|.:.|            ..||:|.|:...:.|           ..|.
Mosquito     4 RTVLITALLCLLASPTTFATRPAWKWLSEPSDFTLSFERELSDLAGSLPV-----------PNRR 57

  Fly    62 DTTD--YRLPTNLVPTHYELYWHPDLETGN--FTGQQRISIKVVEATNQIILHSYLLDITSVYV- 121
            ...|  ||||.|..|.||.|.....:...:  |:|..::..:|:|.|..:.||:..|.:...::
Mosquito    58 QAVDESYRLPNNTSPIHYHLALRTAIHENSRQFSGTVKVLFEVLEPTTTVTLHNRRLTVQRAFLH 122

  Fly   122 -------LNREVEK--FELEEERQFLIITLTEELAVDASITLGIIFGGQMK-DKLVGLYSSTYLN 176
                   ...::|:  ...:.:.:.|.:.:::.|...:...|.:.|.|.:: :..:|.::|:||:
Mosquito   123 EEAVGGGAGAQIEQVAHSTDPDTEHLTLAVSQLLLPGSRYYLRVEFEGALQNNNNMGFFASSYLD 187

  Fly   177 EAGATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNM----QQTESNYLGD 237
            .:|..|.::::|||||:||.||||:|||.:||:|.:.:.|.. .|:||:||    ..|......|
Mosquito   188 NSGNRRYLASSKFEPTHARSAFPCYDEPLLKASFELELTHYK-EYNAVANMPLAGTPTPDPDNAD 251

  Fly   238 YTEAIFETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVT 302
            |..:.||.:..|||||:...|:||..::..          ....||..:...:..:.||.|..:.
Mosquito   252 YVTSRFEVTPLMSTYLLAFAVTDFTIRTAD----------RQTVYARPNVFEETAYPLEAGNRIL 306

  Fly   303 EYYIQYYKVPY--PLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAH 365
            :....|..:.|  .:.|:...||||..:||||:||||.|.|..||::|:.::..|::|:...:||
Mosquito   307 DALSDYMDISYYDYMPKMTQIAIPDRGTGAMENWGLVAYGEPVLLFNPAINTYRNRKSVTTIIAH 371

  Fly   366 EIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSH 430
            |.|||||||||:..||..:|||||||...:|......:|:....|.|.:..:......||..:..
Mosquito   372 EYAHQWFGNLVSPHWWEYIWLNEGFATLYEYYAAQLAYPEGEYWELFTVEVIHSAFGADASETVR 436

  Fly   431 PIVQKVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFL--- 492
            |:.....:|.||.|:|||::|:|.|||:.|...::|...:...:..|:...|.:....|...
Mosquito   437 PMNWNAATPSEIAALFDTVAYDKSGSVLNMFRAVLGDPVWRYGLKTYMTARQLDGATADHLYGGL 501

  Fly   493 ---------TEVEAVVTDLDIKKLMLTWTEQMGYPVLNVSKVADGSFK--VTQQRFLSNPASYEE 546
                     |.:.|.||   :::||.:||.:.|:|||.|.:......:  ::|:||||:    :.
Mosquito   502 QEALVSLAPTLLPATVT---LRQLMDSWTSEPGFPVLTVYRTYGERQEAILSQERFLSS----KR 559

  Fly   547 APSDSAYGYKWSVPITW---FADDGSENSFIYDY---DVDSVGIAVPSEVQWIKLNVNQTGYYRV 605
            .||    |:.:.||..:   .|.|.......|.:   ..|.:...||:: |||..|..|.|||||
Mosquito   560 LPS----GHVYYVPYDFTGGHAPDFEPTPAGYGWLAAKADKIATGVPND-QWIIFNRQQNGYYRV 619

  Fly   606 NYEESLWALLIQQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYV 670
            ||:...|.|||:.|...||:....:|..|:|||:.||.|..|.:.:||.:.:||.:|..:.||..
Mosquito   620 NYDAHNWELLIEVLHNDPAQIHHRNRAQLVNDAYNLARAEWLDFAVPLRLMSYLRRETQYAPWTA 684

  Fly   671 ASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYEEVGWTVDA----DNHLKNRLRVSILTAACAL 731
            |.:.|..|:..|..:..|..:..||..|:..:|..:  .:|:    :..|:..|:..|.|.||.:
Mosquito   685 AGSALTYLYNKLRGTAHYAHFQVYANHLLLDIYPTL--AIDSVAAQETLLQLYLKQFITTWACRV 747

  Fly   732 GVPDCLQQASERFSTFLENPTTRPSPDLREIVYYYGMQQSTSQ-SSWDQLFQLFVAETDASEKLK 795
            |..|||.:..:..:...: ..|...||:...||..|:..::.: ..|  :::.|.:..:.:.:..
Mosquito   748 GHGDCLAKTKQALAAAYQ-ARTPVHPDIATAVYCNGLVDASDEIFVW--VYEQFKSSRNQAHRTV 809

  Fly   796 LMYGLSGVRNSQYLFDFL-----AQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQ 855
            |:..|:..|....|..||     :.|..|..:...:.......| .|:..|...|.:|.  ..|.
Mosquito   810 LIDALACSRQPAQLESFLTTALGSGAEFDALLATERTRIVSAVY-GASREGVDAVLDFL--MVPS 871

  Fly   856 LTTRF--GLNNRNFGRLIAQITANFASSVKLEEVQHFF----SKYPESGAGANSRLEAVETIKYN 914
            ..|.|  .|........::.|.:...:..:|:.:....    |:.|||.|     ..|..|::.|
Mosquito   872 RVTEFVQRLGQSALNSAVSNIASRTNNQPELDRLNALLVSLGSQIPESVA-----TSARSTVQNN 931

  Fly   915 IEWLSRNE 922
            ..|.:..|
Mosquito   932 FNWFNTLE 939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	138/468 (29%)
		ERAP1_C	592..912	CDD:463368	88/335 (26%)
LOC5667739	XP_001689317.3	None