Protein Alignment CG8774 and erap1a

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_692516.3
• Gene: erap1a / 564068
• ZFINID: ZDB-GENE-091113-7
• Length: 933
• Species: Danio rerio
• Alignment Length: 922
• Identity: 308/922 - (33%)
• Similarity: 477/922 - (51%)
• Gaps: 95/922 - (10%)

  Fly    67 RLPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYVL--------- 122
            |||..:.|.||:|..||:|.:..|||:.:|.|:|.:.|..|||||..|.::...:|
Zfish    43 RLPEIVKPQHYDLLIHPNLTSLTFTGEVQIQIEVKQDTRAIILHSKNLQVSKALLLGSRQHHHHQ 107

  Fly   123 NREVEKFELEEERQFLIITLTEELAVD-ASITLGIIFGGQMKDKLVGLYSSTYLNEAGATRTIST 186
            :.::.:||..|:    |...:|....: .|..:.:.|...:.|...|.|...|...:|..|.:::
Zfish   108 DLQISEFEANEQ----IALFSEGFTFEKGSHVVHLEFYANLSDSFHGFYKGQYTTNSGEVRMLAS 168

  Fly   187 TKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESNYLGD-YTEAIFETSVSMS 250
            |:||||:||.|||||||||.||.|.|.|...| .:.::|||.:..:..|.| ..|..|:|.|.||
Zfish   169 TQFEPTHARAAFPCFDEPAFKANFTIRVRRES-RHISISNMPKLRTVELADGILEDQFDTMVKMS 232

  Fly   251 TYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPYPL 315
            ||||..|:.||.|.|   |.:..|.:.|:  |....:|::.|:||:....:.::|.:|:.:||||
Zfish   233 TYLVAFIICDFHSIS---KKSQHGVEISV--YTVPEKISQAEYALDTAVTMLDFYDEYFDIPYPL 292

  Fly   316 TKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTMKW 380
            .|.|:||||||.|||||:|||.||||:.||:||..||:::|..|...:|||:|||||||||||:|
Zfish   293 PKHDLAAIPDFQSGAMENWGLSTYRESGLLFDPEKSSSSDKLGITKVIAHELAHQWFGNLVTMQW 357

  Fly   381 WNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPDEITAI 445
            |||||||||||::|:|..||..||:..:.:.| :......|..|:..||||:...||:|.||:.:
Zfish   358 WNDLWLNEGFAKFMEYVSVNITHPELQVNDYF-LEKCFTALSVDSLSSSHPVSTPVENPAEISEM 421

  Fly   446 FDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVVT---------- 500
            ||.:||.||..::.||...:..|.|:..:.|||.||.:.|||.......:..:.|
Zfish   422 FDDVSYRKGACILNMLRDFLTPEVFKYGIINYLKKHSYQNTVNSHLWESLTNICTSDGLDSGRLK 486

  Fly   501 ---------------------DLDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASY 544
                                 .:|:..:|.|||.|.|:|::.| :|......:.|:|||..
Zfish   487 LDGFCSKHTAETPASKWFKEDSVDVGAIMDTWTLQEGFPLITV-EVKGQEVTLKQERFLKG---- 546

  Fly   545 EEAPSDSAYGYKWSVPITWFADDGSE--NSFIYDYDVDSVGIAVPSEVQWIKLNVNQTGYYRVNY 607
              |.|.::..:.|.||:|:.. .||.  ..|:...:.|.  ..:|.:|:|||.||:..|||.|:|
Zfish   547 --AESSNSSSFLWQVPLTYIT-SGSNAVQRFLLKTERDV--FYLPEKVEWIKFNVDLRGYYIVHY 606

  Fly   608 EESLWALLIQQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPLD----MTAYLAQERDFVPW 668
            |...|..||:||..:...|...||..|::|.|.|....    |:|||    ::.||::|.:.:|.
Zfish   607 ESGGWDCLIKQLRMNHTVFSSNDRASLIHDIFQLVSIE----KVPLDKALNLSLYLSKESEIMPV 667

  Fly   669 YVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYEEV----GWTVDADNHLKNRLRVSILTAAC 729
            ....::|..|:: ||............:|.:..:::.:    .|: |..:..:..||..:|..||
Zfish   668 TQGFSELVPLYK-LMEKRDMQELENQLKSHLVKLFQPLIDRQSWS-DNGSVSERMLRNYLLLFAC 730

  Fly   730 ALGVPDCLQQASERFSTFLEN------PTTRPSPDLREIVYYYGMQQSTSQSSWDQLFQLFVAET 788
            ....|.|:..|::.|..:.|:      ||     |:..:||..|   :.:...||.|.:.:....
Zfish   731 VRRYPSCVSTATQLFHKWKESDGKMWLPT-----DVSLVVYTEG---ARTDDGWDFLLEKYKRSV 787

  Fly   789 DASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQW 853
            ..|||..:...|| .....:...:|.:.||:..|:::||..:.:..::.||.|..:.|:|.:..|
Zfish   788 SPSEKWMIKAALS-YSPLAHKLQWLLERSSEGEIMKTQDLPSMLISVSKNPKGFKLAWDFLKSNW 851

  Fly   854 PQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQHFF-SKYPESGAGANSRLEAVETIKYNIEW 917
            .:|..:|.|.:....|::..:|..:::...|:||:.|| |...:.|:|..|..:|:|.|:.||.|
Zfish   852 GKLVKKFDLGSSAISRVVVGVTDQYSTKEMLDEVELFFGSLAQDQGSGLRSIQQALEKIQQNILW 916

  Fly   918 LSRNEADITDWL 929
            :.||...:..||
Zfish   917 MDRNVPLLKAWL 928

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	184/479 (38%)
		ERAP1_C	592..912	CDD:463368	90/334 (27%)
erap1a	XP_692516.3	M1_APN-Q_like	52..520	CDD:341064	184/478 (38%)
		ERAP1_C	591..911	CDD:463368	90/334 (27%)