Protein Alignment CG8774 and anpepa

DIOPT Version :9

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_001038326.1
• Gene: anpepa / 558452
• ZFINID: ZDB-GENE-030131-4781
• Length: 946
• Species: Danio rerio
• Alignment Length: 926
• Identity: 300/926 - (32%)
• Similarity: 480/926 - (51%)
• Gaps: 111/926 - (11%)

  Fly    67 RLPTNLVPTHYELYWHPDLE---TGN-------FTGQQRISIKVVEATNQIILHSYLLDITSVYV 121
            |||.:|:|..|.::..|.|.   |.|       |||...:.:...:.::::.||.:.:::|:|.|
Zfish    63 RLPDSLIPESYNVFLQPYLYAAITNNYTEQSYLFTGNSTVRVNCTKTSSRVFLHVHNINVTAVEV 127

  Fly   122 LNREV-EKFEL------EEERQFLIITLTEELAVDASITLGII--FGGQMKDKLVGLYSSTY--- 174
            ...:. ||..|      :.|..||.|.|  |:|:..:.|..|.  |.|::.:.|.|.|:|.|
Zfish   128 RKSDTNEKLPLKGYQIFKNETNFLDIHL--EVAIKENGTYDIFTEFEGELLEDLTGFYASRYTGK 190

  Fly   175 -LNEAGATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVH-PSGSYHAVSNMQQTESNYLG- 236
             .::....|.::|:..:||.||..|||||||||||.|.||::| |.         .:..||..|
Zfish   191 GTDDEDEERFLATSLLQPTDARTVFPCFDEPAMKAVFTITIIHRPE---------IRARSNEDGD 246

  Fly   237 ---------DYTEAIFETSVSMSTYLVCIIVSD-----FASQSTTVKANGIGEDFSMQAYATSHQ 287
                     |:....|:.:..||:||:..|:.|     :.|:.|..|.:..|...::.|
Zfish   247 PRTIQINGTDWIRTTFKPTKKMSSYLLGFIIYDTHTFSYVSKGTRTKIHVHGRSEAIDA------ 305

  Fly   288 INKVEFALEFGQAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSS 352
             ...::|||..:.:..:|...:.:.||::|:|..|:|||...|||:||.::|:|:.||||...:|
Zfish   306 -GHADYALETTETILSHYENIFGLRYPMSKIDQIALPDFGVRAMENWGFISYQESGLLYDKETAS 369

  Fly   353 TANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVAL 417
            |.:::.:...:|||:|||||||||||.|||||||.||||.||.||||.||  .|.:.:...:..:
Zfish   370 TFDEEQVTTLIAHELAHQWFGNLVTMSWWNDLWLKEGFATYMSYKGVEAV--GWDLKDLIVLREI 432

  Fly   418 QPVLLYDAKLSSHPI---VQKVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLV 479
            |.....|:..:|||:   ...|::..:|:.:||.|:|.||.:|:|||.|.:|..:|.:.|..||.
Zfish   433 QTAFQMDSLNTSHPLSMNAYDVQTSSQISELFDDITYSKGAAVLRMLATRMGENEFMKGVKMYLS 497

  Fly   480 KHQFNNTVTDDFLTEVEAVVTDLDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASY 544
            |.||.|||..| |.|...:.|.:.:.:.|.||||::|||||.:  :.| :...:|::||..
Zfish   498 KFQFENTVPKD-LWECLNMDTHIKVDEFMKTWTEEVGYPVLTI--ITD-TGDTSQEQFLLK---- 554

  Fly   545 EEAPSDSAYGYKWSVPI-------------TWFADDGSENSFIYDYDVDSVGIAVPSEVQWIKLN 596
            :|...||.    |.:||             .:|.|.|.:.  |.|:.:        .:..|:..|
Zfish   555 KEGGHDSL----WHIPIKYMTLKAGVKEFPNFFTDKGPDP--IPDFKI--------GKDNWLLAN 605

  Fly   597 VNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQ 661
            :|.||:|||||:|..|..|..||..:.....:.:||.|::|||.||.|::|:..|.|::|.||..
Zfish   606 INCTGFYRVNYDEENWNRLTAQLQKNHRIIPLINRGQLIDDAFNLARAHRLNVTIALNLTKYLIN 670

  Fly   662 ERDFVPWYVASNKLRSLHRSLMF--SEGYVSYLTYARSLIAGVYEE-----VGWTVDADNHLKNR 719
            :.:::||..|...|...  :|||  ||.|...:.|.|:|:..:|||     :..|:..:.:....
Zfish   671 DLEYIPWESALKNLDFF--TLMFDRSEVYGPIMKYLRNLVTPLYEEYEEYTINGTIPIEKYTDQC 733

  Fly   720 LRVSILTAACALGVPDCLQQASERFSTFLENPTTRPSPDLREIVYYYGMQQSTSQSSWDQLFQLF 784
            .:|:.:|.||:.|:|:|:..|.:.||.: :|.:....|:||..||...: .|..:..|:.:::.:
Zfish   734 NQVNAITVACSNGLPECITMAKDLFSDY-KNGSNPIHPNLRRAVYCSAV-ASGDEDDWEYVWEEY 796

  Fly   785 VAETDASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFY 849
            ...|.|:||.||.|.||..:....|..:| |.:.:.|.:|..|..:.:.|||.|..|:|:.|:|.
Zfish   797 QKATVAAEKDKLRYALSCTKEIWLLNRYL-QYTLEPSKIRKMDMVSTISYIAQNVAGQPLAWDFI 860

  Fly   850 REQWPQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQHFFSK--YPESGAGANSRLEAVETIK 912
            |..|..:|..:|....:.|.|:..:|..|::.|:|||::....:  ..:....|.:..:.:|...
Zfish   861 RGHWSYITQEYGAGIISLGSLLDVVTKRFSTEVELEELKQLQREQIQDDKWIAARALEQVIERTA 925

  Fly   913 YNIEWLSRNEADITDW 928
            .||.|:..|:..:.||
Zfish   926 ANIIWVKENKQVVKDW 941

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	Peptidase_M1	67..454	CDD:279741	145/428 (34%)
		M1_APN_2	75..518	CDD:189008	168/484 (35%)
		ERAP1_C	593..910	CDD:288671	100/325 (31%)
anpepa	NP_001038326.1	Peptidase_M1	63..472	CDD:279741	145/428 (34%)
		M1_APN_2	71..535	CDD:189008	168/484 (35%)
		ERAP1_C	602..923	CDD:288671	100/325 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100307
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X67
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.820