Protein Alignment CG8774 and SP1029

DIOPT Version :9

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_001263065.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Alignment Length: 910
• Identity: 290/910 - (31%)
• Similarity: 462/910 - (50%)
• Gaps: 75/910 - (8%)

  Fly    66 YRLPTNLVPTHYELYWHPDLETG---NFTGQQRISIKVVEATNQIILHSYLLDITSVYVLNRE-- 125
            |||||:|.|..|.|.....||..   .|:|..:|.|:.:|.|..:.|||..|.|....:..|:
  Fly    32 YRLPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALENTKNVTLHSKNLTIDESQITLRQIG 96

  Fly   126 --------VEKFELEEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNE-AGAT 181
                    |....:.....|.|:...:||....:..|.:.|...:..:|.|.|.|:|.:. |..|
  Fly    97 GEGKKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMPFAADLNRQLEGYYRSSYKDPVANLT 161

  Fly   182 RTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTES---NYLGDYTEAIF 243
            :.||.|:|||..||.||||||||..||.|.:|:.:.. .|.|:|||.:.|:   ..|.||....|
  Fly   162 KWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHK-KYTAISNMPEKETKPHETLADYIWCEF 225

  Fly   244 ETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQY 308
            :.||.||||||...|:||:.:.:|:..:.:     .:.:|..:.|::.::|.:||..|.:||.|:
  Fly   226 QESVPMSTYLVAYSVNDFSHKPSTLPNSAL-----FRTWARPNAIDQCDYAAQFGPKVLQYYEQF 285

  Fly   309 YKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFG 373
            :.:.:||.|:|..|:|||::||||:||||||||.||||..::||.|:||.:|..:|||:||||||
  Fly   286 FGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAAHSSLADKQRVASVVAHELAHQWFG 350

  Fly   374 NLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVES 438
            ||||||||.|||||||||.|:...||..::|:|..:||..:..|..:...||..|||||.:.::.
  Fly   351 NLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQESLSNLLTIFRRDALESSHPISRPIQM 415

  Fly   439 PDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDF---LTEV----E 496
            ..||:..||.|||:||.:|:||:...:|.|.|...:..||.|..:.|...|:.   ||:.    .
  Fly   416 VSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKNAEQDNLWESLTQAAHKYR 480

  Fly   497 AVVTDLDIKKLMLTWTEQMGYPVLNVSK-VADGSFKVTQQRFLSNPASYEEAPSDSAYGYK---W 557
            ::....|||.:|.:||.|.||||:||:: .|..:.|:.|:|:|.|        :..|..|:   |
  Fly   481 SLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAKLNQERYLLN--------TQVARAYRGGCW 537

  Fly   558 SVPITWFADDGSENSFIYDY---------DVDSVGIAVPSEV-------QWIKLNVNQTGYYRVN 606
            .||:::      ....:.|:         :....|.::|..:       ||:..|...:..|:||
  Fly   538 WVPLSY------TTQAVQDFNNTAPKAWMECGKNGESLPKTIQDLPGPDQWVIFNTQLSTLYKVN 596

  Fly   607 YEESLWALLIQQLTTSP-ARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYV 670
            |:...|.|||:.||... .|..:.:|..|::||..||...:..|:|.:.:..||.:||:::||..
  Fly   597 YDAQNWKLLIETLTNGDFERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYLQREREYLPWKS 661

  Fly   671 ASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYEEVGWTVDADNHLKNR----LRVSILTAACAL 731
            |...|:.:.|.:..:..:..:..|.:.||..:||.:....|..:.:..:    |:..::..||..
  Fly   662 AFENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHLNGINDTFSAIPQQDQVLLKTMVVNWACQY 726

  Fly   732 GVPDCLQQASERFSTFL--ENPTTR-PSP-DLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASE 792
            .|.||:.||...:..:.  .||..: |.| ::|..||...::.. |.|.|:.|:..:.....|:|
  Fly   727 QVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTVYCTSIKHG-SDSDWEFLWTRYKKSNVAAE 790

  Fly   793 KLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLT 857
            |..::..|...|....|..:|......:..:|.||.....|.:|.|.||..:..:::.:....:.
  Fly   791 KRTILTALGCSREVWLLQRYLELTFDPKEAIRKQDSMWAFQAVAFNEVGFLLAKKYFMDNVDFIY 855

  Fly   858 TRFGLNNRNFGRLIAQITANFASSVKLEEVQHFFSKYPESGAGANSRL-EAVETIKYNIEWLSRN 921
            ..:....::..||::.::....:.....|.:.|.:...:|..|....: :.:|.:..|::|..||
  Fly   856 KFYHPLTKDMSRLLSPLSEQVITLSDFNEFKDFVNNSRQSLKGLEQAIQQTLEIMLTNVQWKERN 920

  Fly   922  921
              Fly   921  920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	Peptidase_M1	67..454	CDD:279741	165/403 (41%)
		M1_APN_2	75..518	CDD:189008	182/466 (39%)
		ERAP1_C	593..910	CDD:288671	75/326 (23%)
SP1029	NP_001263065.1	Peptidase_M1	33..431	CDD:279741	165/403 (41%)
		M1_APN_2	43..502	CDD:189008	182/464 (39%)
		ERAP1_C	583..908	CDD:288671	75/325 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462032
Domainoid	1	1.000	98	1.000	Domainoid score	I364
eggNOG	1	0.900	-	-		E1_COG0308
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100307
Panther	1	1.100	-	-	P	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X67
	9	8.750