Protein Alignment CG8774 and enpep

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_001186660.2
• Gene: enpep / 504088
• ZFINID: ZDB-GENE-050309-218
• Length: 951
• Species: Danio rerio
• Alignment Length: 889
• Identity: 345/889 - (38%)
• Similarity: 527/889 - (59%)
• Gaps: 32/889 - (3%)

  Fly    64 TDYRLPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYVLNRE--- 125
            :::|||..::|.||:|:..|||.|..:||...:.:|:.:.:..:.||.....:|.:..|.|.
Zfish    77 SNFRLPDYILPFHYDLHMEPDLNTDIYTGDVSVHLKLTQPSQHLWLHIRDTFVTVMPSLQRSSPS 141

  Fly   126 -VEKFELEE-----ERQFLIITLTEELAV---DASITLGIIFGGQMKDKLVGLYSSTYLNEAGAT 181
             |...:|::     .::::::...|:|:|   |....|.:.|.|.:...|||.|.:|| .|.|.|
Zfish   142 GVTSVKLKQCFEYKPQEYVVVEAAEQLSVTGPDEHYVLTLHFQGWLNGSLVGFYRTTY-QENGVT 205

  Fly   182 RTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESNYLGDY-TEAIFET 245
            :.|:.|..|||.||::|||||||..|||:.|::.|.| :|.|:|||...::..|.:. |:..|..
Zfish   206 KKIAATDHEPTDARKSFPCFDEPNKKATYTISITHDS-TYKALSNMPVEKTEKLSEQKTKTSFMK 269

  Fly   246 SVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYK 310
            ||.|||||||..|..|.....|.| .||    .::.||...||:...:|.:..|.:.:|:.:|:.
Zfish   270 SVKMSTYLVCFAVHQFDFVERTSK-RGI----PLRIYAQPLQISTAAYAADVTQVIFDYFEEYFD 329

  Fly   311 VPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNL 375
            :.|.:.|||..|||||.:||||:|||:|||||.||:|...||:.|||.:|..:|||:.||||||:
Zfish   330 MEYSIQKLDKIAIPDFGTGAMENWGLITYRETNLLFDEKESSSVNKQRVASVIAHELVHQWFGNI 394

  Fly   376 VTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPD 440
            |||.||:|||||||||.:.:|.||.....||||.:...|..:.||::.||.||||||:..|.||.
Zfish   395 VTMDWWDDLWLNEGFASFFEYIGVEEAEHDWGMRDVMLINDVYPVMVDDALLSSHPIIVDVSSPA 459

  Fly   441 EITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVVTDLDIK 505
            |||::||.|||.||.|::||||.|:|.:.|.:....||..:.|.|..|.||...: |..:.|.:.
Zfish   460 EITSVFDAISYNKGASILRMLEDLLGRDTFRDGCRRYLKTYLFQNAKTSDFWKAL-ADESGLPVA 523

  Fly   506 KLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFADDGSE 570
            .:|.|||:|||||||:::. .|...|:||.|||.:|.:....|: :..||||::|:.|.|.|.:.
Zfish   524 DIMDTWTKQMGYPVLSLTN-TDTEAKLTQTRFLLDPNADPSQPT-TPLGYKWTIPVKWKALDSTN 586

  Fly   571 NSFIYDYDVDSVGIAVPSEVQ--WIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGH 633
            ||||::.......|:..|...  .||:|.:..|:||||:.:.:|:.:.:||......::..||..
Zfish   587 NSFIFEKGQTEAVISGYSHATNGLIKVNKDHMGFYRVNHHDQMWSDIAEQLLMDHQVYDATDRSS 651

  Fly   634 LLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSLMFSEGYVSYLTYA--- 695
            .::|.|||..|:.:.|....::|.|||.|.:::.|...|..:..:..  |.::..|.|..:.
Zfish   652 YIDDIFALGRADMVDYGNAFNLTRYLADETEYIVWDRVSASISYVRE--MLADDTVLYPLFQKLF 714

  Fly   696 RSLIAGVYEEVGWTVDADNHLKNRLRVSILTAACALGVPDCLQQASERFSTFLENPTTRPSPDLR 760
            |..:..:..|:||. |..|..:..||..:|..||.:|..:.|.|||:.|:.:::........:||
Zfish   715 RGHVQKISRELGWK-DEGNQTQRLLREIVLGIACQMGDQEALDQASDIFNKWIKGTIGSVPVNLR 778

  Fly   761 EIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRS 825
            .:||.|||..|.::.||:.:||.:::.|.|.||.||:|||:.|:|. :|...|.:|:.:|||:||
Zfish   779 LLVYRYGMMNSGTEESWEIMFQKYLSATLAQEKDKLLYGLASVKNI-HLLHRLLEATKNESIIRS 842

  Fly   826 QDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQHF 890
            ||.||.|||::.:..|:.:.|::....|..|..|:.:|:||.|||.|:||..::|:::|.:::||
Zfish   843 QDVFTLVQYVSRSSDGKIMAWDWMTLNWDYLVNRYTINDRNLGRLPARITTTYSSNLQLWKMEHF 907

  Fly   891 FSKYPESGAGANSRLEAVETIKYNIEWLSRNEADITDWLSGTAS 934
            |:.:|.:|||...|.:|:||:|.||||:.||:.:|..||....|
Zfish   908 FALHPNAGAGEMPRKQALETVKNNIEWVERNKDEIRFWLENNVS 951

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	188/450 (42%)
		ERAP1_C	592..912	CDD:463368	111/322 (34%)
enpep	NP_001186660.2	None