Protein Alignment CG8774 and CG46339

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Alignment Length: 977
• Identity: 277/977 - (28%)
• Similarity: 462/977 - (47%)
• Gaps: 92/977 - (9%)

  Fly    21 TATVVVAVQKAQLERDLRDVQDK---IDVFEEWSGESRTRMKREDTTDYRLPTNLVPTHYELYWH 82
            |.|..:|:..:..:.::|.|..|   |.|.|..:||......:......:|.....|.||.|...
  Fly   240 TVTTTLAMPASSEKPEIRMVDPKVGDIPVVEPAAGEVEDNTTKPINRPLKLYEGWRPLHYSLLIE 304

  Fly    83 PDLET----GNFTGQQRISIKVVEATNQIILHSYLLDITSVYVL-------NREVEKFELE---- 132
            |.:.|    |:.|.:....:..|.:...|:|..:.:.|::|.|:       :...|:.:|:
  Fly   305 PSVATSISNGSLTIEIERDVSKVTSWEPIVLDVHNVSISNVRVIRALADGASNASEEQDLDFDSD 369

  Fly   133 --EERQFLIITLTEELAVDAS--ITLGIIFGGQMKDKLVGLYSSTYLN-EAGATRTISTTKFEPT 192
              |:....:|.|::.|||:..  :.|.:.|..|:.|.|.|:|.::|.| :......:.:|:|.|.
  Fly   370 YGEDNATFVINLSKTLAVETQLRVLLSLDFVSQVTDTLQGIYKTSYTNPDTKNEEWMISTQFSPV 434

  Fly   193 YARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTES-NYLGDYTEAIFETSVSMSTYLVCI 256
            .||:||||||.|.|||.|:|::|.|.....|:|||.::.| .:...:....|||:..|.||||..
  Fly   435 DARRAFPCFDRPDMKANFSISIVRPMQFKMALSNMPKSGSRRFRRGFIRDDFETTPKMPTYLVAF 499

  Fly   257 IVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPYPLTKLDMA 321
            |||:........:.:|:..  .::.:.....:....:|.:..:....||..::.:...|.|:|:.
  Fly   500 IVSNMVDSRLASQDSGLTP--RVEIWTRPQFVGMTHYAYKMVRKFLPYYEDFFGIKNKLPKIDLV 562

  Fly   322 AIPDFASGAMEHWGLVTYRETALLYDPSY---SSTANKQSIAGTLAHEIAHQWFGNLVTMKWWND 383
            ::|||...|||:|||:|:|::|||.....   ||:.:.|.:||.:|||:||||||||||.|||:|
  Fly   563 SVPDFGFAAMENWGLITFRDSALLVPEDLQLASSSEHMQVVAGIIAHELAHQWFGNLVTPKWWDD 627

  Fly   384 LWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPDEITAIFDT 448
            |||.||||.||.||.:...||::..::...::..:..:.:||..:||.|...|.|.:::..|||.
  Fly   628 LWLKEGFACYMSYKALEHAHPEFQSMDTLTMLEFKESMEHDADNTSHAISFDVRSTNDVRRIFDP 692

  Fly   449 ISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDD---FLT----EVEAVVTDLDIKK 506
            |||.||..::|||.::||...|..|..:.|.|..:.|...||   .||    |...:..||.:|:
  Fly   693 ISYSKGTILLRMLNSIVGDVAFRSATRDLLKKFAYGNMDRDDLWAMLTRHGHEQGTLPKDLSVKQ 757

  Fly   507 LMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPS-DSAYGYKWSVPIT-------- 562
            :|.:|..|.||||:||.: ......:.|:|:|        .|| ::|....|.:|||
  Fly   758 IMDSWITQPGYPVVNVER-RGADLVLRQERYL--------LPSKNTADQSTWFIPITFETDELRK 813

  Fly   563 -------WFADDGSE-----NSFIYDYDVDSVGIAVPSEVQWIKLNVNQTGYYRVNYEESLWALL 615
                   |...:..|     |.|.:..:.|:|          |.||:|:.|||||||:.:.|..|
  Fly   814 GDNIPTHWMRSEDEEELIVGNVFAHSSNSDNV----------IYLNLNRQGYYRVNYDMTSWLAL 868

  Fly   616 IQQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVP----WYVASNKLR 676
            .:..:|.|.    ..|..||:||..|:.|..|:|.|||   .:|.:..|.|.    |..|...|.
  Fly   869 KKNFSTLPR----ITRAQLLDDALHLSQAEYLTYDIPL---TFLMELFDAVDDELLWIAAKPGLN 926

  Fly   677 SLHRSLMFSEGYVSYLTYARSLIAGVYEEVG-WTVDADNHLKNRLRVSILTAACALGVPDCLQQA 740
            .|..:|.....|.::..:.:.::...::..| ...|.::||:.:.|..:...||......|.|:|
  Fly   927 YLIYNLKREPAYETFRAFMKFIVRPAFDHYGLHEPDNESHLQLKHRALVAYFACKFNYDRCTQKA 991

  Fly   741 SERFSTFLENPTTRP-SPDLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVR 804
            ..:|..::.:|...| .|:|:.::|...:.:.:| ..|...::.:...|.||||.:::..|....
  Fly   992 QMKFREWMRDPKNNPIKPNLKSVIYCTSLAEGSS-PEWYFAYKQYKTTTSASEKEEILTSLGCTT 1055

  Fly   805 NSQYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGR 869
            ....|..:|....:..|.:..||.....:.:|:|.:|..:.::|.:....::...:|........
  Fly  1056 KPWLLSKYLNMTINPTSGILKQDGALAFRAVASNAIGHEIAFDFLQGNIKEIVEYYGDGFSTLSE 1120

  Fly   870 LIAQITANFASSVKLEEVQHFFSKYPESGAGA-NSRLE-AVETIKYNIEWLSRNEADITDWLSGT 932
            :|..:|..........::....:...:.|..| .|.:| |:|.:..||.|.|.:...:.::|.|.
  Fly  1121 MIKSLTIYMNKDYHKHQLLDLAATCRKLGLHAVESAIELALEQVNNNIYWRSHSYHSLKNFLEGI 1185

  Fly   933 AS 934
            .|
  Fly  1186 VS 1187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	156/468 (33%)
		ERAP1_C	592..912	CDD:463368	78/327 (24%)
CG46339	NP_001263001.1	M1_APN-Q_like	297..764	CDD:341064	156/468 (33%)
		ERAP1_C	846..1126	CDD:463368	71/287 (25%)