Protein Alignment CG8774 and superdeath

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_651674.3
• Gene: superdeath / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Alignment Length: 996
• Identity: 325/996 - (32%)
• Similarity: 497/996 - (49%)
• Gaps: 115/996 - (11%)

  Fly     1 MFLSGYWLQVVLSWAVVAFATATVVVAVQKAQLERDLRDVQDKIDVFEEWSGESRTRMKREDTTD 65
            :.|:.:::..:|:...:.:..||.      |:||.|..:     ||........|.:...:||..
  Fly    54 ILLASFFICTLLAVGFIVYNFATC------AELEPDSDE-----DVVCTSYHLRRLKAGHDDTPK 107

  Fly    66 Y----RLPTNLVPTHYELYWHPDLETGNFT--GQQRISIKVVEATNQIILHSYLLDIT----SVY 120
            |    |||.::.|..|.:...|.| :||||  |..:|.|:|:|....|.:|:..|:|:    ||:
  Fly   108 YDRDVRLPHSIRPLKYNITIEPQL-SGNFTFAGSVQIRIRVLEDCYNITMHAEELNISRSDASVH 171

  Fly   121 -VLNR--------EVEKFELEEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTY-- 174
             |.|.        .:.|..|...:||.:|.|.::|..|....:.:.|.|.::|.|.|.|.|:|
  Fly   172 RVQNNGEPEGDGLRIHKQYLVGAKQFFVIELYDKLLKDVEYVVHLRFDGIIEDYLQGFYRSSYEV 236

  Fly   175 LNEAGATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESN------ 233
            .||   ||.:::|:|:.|.||:|||||||||:||.|.:.:..|. :...:|||....||
  Fly   237 HNE---TRWVASTQFQATDARRAFPCFDEPALKANFTLHIARPR-NMTTISNMPIVSSNDHATMP 297

  Fly   234 -YLGDYTEAIFETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEF 297
             |:.|:    |..|:.||||||...:|||...|:.          :...:|.:..|...|:||..
  Fly   298 SYVWDH----FAESLPMSTYLVAYAISDFTHISSG----------NFAVWARADAIKSAEYALSV 348

  Fly   298 GQAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGT 362
            |..:..:...::.|.:||.|:||.|:|:|.:||||:|||:|:||||:||||..::..|||.:|..
  Fly   349 GPRILTFLQDFFNVTFPLPKIDMIALPEFQAGAMENWGLITFRETAMLYDPGVATANNKQRVASV 413

  Fly   363 LAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKL 427
            :.||:||||||||||..||:|:|||||||.||:|...:||.|:|..|:||.:..||.|...||..
  Fly   414 VGHELAHQWFGNLVTPSWWSDIWLNEGFASYMEYLTADAVAPEWKQLDQFVVNELQAVFQLDALS 478

  Fly   428 SSHPIVQKVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDD-- 490
            :||.|..:|.:|.||:.|||.|||.||.::|||:...:....|...::.||.:..:|:...||
  Fly   479 TSHKISHEVFNPQEISEIFDRISYAKGSTIIRMMAHFLTNPIFRRGLSKYLQEMAYNSATQDDLW 543

  Fly   491 -FLTEVEAVVTDL-----DIKKLMLTWTEQMGYPVLNVSKVADGS-FKVTQQRFLSNPASYEEAP 548
             ||| |||..:.|     .:|::|.|||.|.||||:.||:..:.. .::.|.||:....:.|:.
  Fly   544 HFLT-VEAKSSGLLDDSRSVKEIMDTWTLQTGYPVVKVSRHPNSDVIRLEQVRFVYTNTTREDE- 606

  Fly   549 SDSAYGYKWSVPITWFADDGSENSF-------------IYDYDVDSVGIAVPSEVQWIKLNVNQT 600
                 ...|.:|||:..|  ||.:|             :|:.:...:.:|     :|...||.||
  Fly   607 -----SLLWYIPITFTTD--SELNFANTRPTTWMPRTKLYELENRELSLA-----KWFIFNVQQT 659

  Fly   601 GYYRVNYEESLWALLIQQLTTSPARFEI--ADRGHLLNDAFALADANQLSYKIPLDMTAYLAQER 663
            |||||||:...|..:.:.|.......:|  |:|..|::|...||..:.|||:..:::|.||..|.
  Fly   660 GYYRVNYDLENWMAITEHLMDVDNFEDIAPANRAQLIDDVMNLARGSYLSYETAMNLTRYLGHEL 724

  Fly   664 DFVPWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYEEVGWTVDADNH---LKNRLRVSIL 725
            ..|||..|.:....:....:.|..|.....|....:..||::||:....|..   |....|..||
  Fly   725 GHVPWKAAISNFIFIDSMFVNSGDYDLLKNYLLKQLKKVYDQVGFKDSQDESEDILVKLKRADIL 789

  Fly   726 TAACALGVPDCLQQASERFSTFLENPTTRPS----PDLREIVYYYGMQQSTSQSSWDQLFQLFVA 786
            :.||.||..:|:.:||..|..:::.|....:    |:||.:||...:|..| :..||..|:.|:.
  Fly   790 SMACHLGHQECIAEASRHFQNWMQTPNPDSNNPIVPNLRGVVYCSAIQYGT-EYEWDFAFERFLK 853

  Fly   787 ETDASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYRE 851
            .....||..|:..|...:....|:.||.:..|.:.| |.||.|.....::...||:.:.::|.|.
  Fly   854 TNVPGEKDLLLNALGCSKEPWLLYRFLRRGISGQHI-RKQDLFRVFAAVSTTVVGQNIAFDFLRN 917

  Fly   852 QWPQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQHFFS----KYPESGAGANSRLEAVETIK 912
            .|.::.|..|....:...|....|..|.|..:|.|.::|..    .|.....      :.||.|:
  Fly   918 NWQEIKTYMGSQMSSIHTLFKFATKGFNSKFQLGEFENFVKDAHWDYDRPVQ------QIVEHIE 976

  Fly   913 YNIEWLSRNEADITDWLSGTA 933
            .:::|:::|...|..||...|
  Fly   977 TSVDWMNKNYKSIVRWLENEA 997

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	184/469 (39%)
		ERAP1_C	592..912	CDD:463368	94/332 (28%)
superdeath	NP_651674.3	M1_APN-Q_like	121..571	CDD:341064	184/469 (39%)
		ERAP1_C	651..976	CDD:463368	94/332 (28%)