Protein Alignment CG8774 and CG4467

DIOPT Version :9

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Alignment Length: 1010
• Identity: 258/1010 - (25%)
• Similarity: 434/1010 - (42%)
• Gaps: 174/1010 - (17%)

  Fly    68 LPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYVLNREVEKFELE 132
            |||::.|..|.:..||:|.|.:..||..|.:.|.:.||.|:||...|::|...::....:.:.|:
  Fly   138 LPTSVRPLRYMVTIHPNLTTLDVKGQVTIDLHVEKETNFIVLHIQDLNVTEKAIVTPGPKGYALK 202

  Fly   133 -------EERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNEAGATRTISTTKFE 190
                   ..||.|.|.:.|.|...::.||.:.:..::..:..|.|...|.:..|..|.::.|.|.
  Fly   203 IVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQYESSNGVERLLAATVFR 267

  Fly   191 PTYARQAFPCFDEPAMKATFAITV-------------VH-------------------------- 216
            |..||:||||||||.::|.|.|:|             ||
  Fly   268 PNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSNSIVHTTEDVGFYMGTGLLRDDFIETPPLPA 332

  Fly   217 ----------------PSGSYHAV------SNMQQTESNYLGDYTE-------------AIFETS 246
                            ||.:|...      |.:...:|..|.:||:             .....:
  Fly   333 DAVAWVVSDFQRESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGKNPPVRNITALTHSLN 397

  Fly   247 VSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQA-----------------YATSHQINKVEFA 294
            |:::......:|....:.:..|..||.|:..::.:                 ||....:.:..|.
  Fly   398 VNLTPRQNLTVVQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKRAPSYTFYAPRDLLIRSSFI 462

  Fly   295 LEFGQAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSI 359
            |...:.|.||...:..:.|||||:|..|:|......:...||||.: |:.|.|||..::...|..
  Fly   463 LHTSRDVLEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLK-TSFLTDPSSITSEQYQFS 526

  Fly   360 AGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHP---DWGMLEQFQIVALQPVL 421
            |..:|..:..|:||.:.:.|...|:||.||.   :||.|::|:.|   .|.:.|.:.:......|
  Fly   527 ALRIAEAMVRQFFGGITSRKVLKDVWLWEGL---IQYLGIHALAPLQETWPLREMYLLKMATAAL 588

  Fly   422 LYDAKLSSHPIVQKVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNT 486
            ..||......|:............|    .:|..::..||.|.:|.::|...:.::|..::|...
  Fly   589 DIDAIQGWDSIMNGTSHDGNNEEFF----VQKTAAIFSMLHTAIGEDRFRGCLGSFLKVNRFRTA 649

  Fly   487 VTDDFLTEVEAVVT-----DLDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEE 546
            ...|..|    :.|     ..:||.:|..||.|.|:|:|.|:|:.: |..::|:.|  .||.:..
  Fly   650 EPTDLWT----ICTKKANGSKNIKDMMTLWTHQPGFPLLTVTKMGN-SISISQRPF--RPAEFLA 707

  Fly   547 APSDSAYG-------------------------------YKWSVPITWFADDGSENSFIYDYDVD 580
            ...||..|                               .||..|:|:..|..:.:..::..:||
  Fly   708 IHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKVAPHMKWIFPVTYVTDINNVSETLWMQNVD 772

  Fly   581 SVGIAVPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLNDAFALADAN 645
             |...||..|:|||:|..|.|||||.|.:..||.||::|..:|.||...||..:|:|||.|..||
  Fly   773 -VTFNVPENVKWIKVNAIQNGYYRVVYNDDNWASLIEELAANPNRFTSEDRLGMLSDAFTLCHAN 836

  Fly   646 QLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYEEVGWTV 710
            .|..:|.::|..||..|..:.|..:|...|....|.|.:||.::....:.:..|:.|.|:|||:.
  Fly   837 LLPCEITMNMIQYLPSETHYGPMALALRHLEKWRRILKYSECFLMLSEFIKMKISTVMEKVGWSD 901

  Fly   711 DADNHLKNR-LRVSILTAACALGVPDCLQQASERFSTFLENPTTRPSPDLREIVYYYGMQQSTSQ 774
            |.|  :..| ||..:|.|:......|.:.:|....:.:|....|...|:|||:| |.|...|...
  Fly   902 DGD--VATRLLRPEVLLASVLWEDIDSITKAKNMLNQYLYYNGTAIPPNLREVV-YTGSILSGEY 963

  Fly   775 SSWDQLFQLFV-----AETDASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQY 834
            ..|...::.||     :||.. |:::|:..|...::: :|.:.|.   |..:::.:::....::.
  Fly   964 IYWQHCWERFVNLQRTSETFV-ERMQLLRALGRTKDA-WLQNRLL---SHVTMLPTEEVVQVLKA 1023

  Fly   835 IAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQ---HFFSKYPE 896
            ||..|.|..:...|.:.:|.:|..|.|....:|.::|:.||...|:....:|::   |.|.:
  Fly  1024 IAGTPTGGAMACRFLQAKWFELEKRLGPGTISFAKVISAITQYGATKFDYDELKSLVHRFGR--- 1085

  Fly   897 SGAGANSRLEAVETIKYNIEWLSRNEADITDWLSG 931
             |.|.:.....:.::..|:||::|::..:..|:.|
  Fly  1086 -GHGMSVLNMTLSSVASNVEWVARSQTSLYKWVEG 1119

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	Peptidase_M1	67..454	CDD:279741	115/486 (24%)
		M1_APN_2	75..518	CDD:189008	129/548 (24%)
		ERAP1_C	593..910	CDD:288671	95/325 (29%)
CG4467	NP_001036747.1	Peptidase_M1	138..593	CDD:279741	112/458 (24%)
		GluZincin	145..682	CDD:301352	129/548 (24%)
		ERAP1_C	784..1078	CDD:288671	91/301 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920