Protein Alignment CG8774 and CG5849

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_650979.1
• Gene: CG5849 / 42556
• FlyBaseID: FBgn0038897
• Length: 968
• Species: Drosophila melanogaster
• Alignment Length: 1022
• Identity: 253/1022 - (24%)
• Similarity: 415/1022 - (40%)
• Gaps: 197/1022 - (19%)

  Fly    16 VVAFATATVVVAVQKAQLERDLRDVQDKIDVFEEWSGESRTRMKREDTTDYRLPTNLVPTHYELY 80
            ||...|..::|:....:.||.|                             |||....|..|:|:
  Fly     8 VVVLVTLGLLVSGSMGERERSL-----------------------------RLPNATYPLFYQLH 43

  Fly    81 WHPDLETGN--FTGQQRISIKVVEATNQIILHS-YLLDI------------------------TS 118
            ...|:..|.  |:|...|.:.:.::||:|:||: .|.||                        |:
  Fly    44 ISSDIHKGQLLFSGNATIDVAIRQSTNEIVLHAKNLTDIQITVHRLMAEGSEIVDDLTHTLHPTA 108

  Fly   119 VYVLNREVEKFELEEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNEA-GATR 182
            ..::...:|.::..||.|              ...|.|::...|..:..|||...|.:|. ..|.
  Fly   109 ALLIIHPIENYQAFEEGQ--------------QYRLEILYTAIMASRPAGLYYMDYRDEENNHTV 159

  Fly   183 TISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESNYLGDYTEAIFETSV 247
            .::.|:.||||.|..|||:|||..|:.|:|.:.|.| |:.|:|||...|....||.....|.|:.
  Fly   160 YVAATQCEPTYGRLIFPCYDEPGFKSNFSIKITHGS-SHSAISNMPVKEVLAHGDLKTTSFHTTP 223

  Fly   248 SMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVP 312
            .:|||||..::|||.|.|.|.:  ||    :...|.:.....|.:.||:...........|:.|.
  Fly   224 PISTYLVAFVISDFGSISETYR--GI----TQSIYTSPTSKEKGQVALKNAVRTVAALEDYFGVS 282

  Fly   313 YPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVT 377
            |||.|||..|:......|||:|||:||::..||.:.|......|..:. |..||||||||||||:
  Fly   283 YPLPKLDHVALKKNYGAAMENWGLITYKDVNLLKNISSDGQKRKLDLI-TQNHEIAHQWFGNLVS 346

  Fly   378 MKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPDEI 442
            .:||...|:|||||.|..|...:.::|:..|::.|..........|::....||:...||...:|
  Fly   347 PEWWTYTWMNEGFATYFSYVITDLIYPNDKMMDMFMTHEADSAYSYNSFFDVHPMSHYVEGEKDI 411

  Fly   443 TAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVVTDLD---- 503
            ..:||.|||::|..||:|.......:.|...::::|.|:::  :|.:: |...:|:.::|.
  Fly   412 MGVFDIISYKRGACVIKMFHHAFRQKLFVRGISHFLEKYRY--SVANE-LNLFDALHSELQDDEY 473

  Fly   504 ---------IKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSV 559
                     |:::||:||.....|:|.|::..:.:.....||            |.......|.:
  Fly   474 FSHQPWASRIREIMLSWTHSEWLPILVVTRNYENNTITFTQR------------SVHMKDELWWI 526

  Fly   560 PITWFADDGSENSFIYDYDVDSVGIAVPSEVQ----------------WIKLNVNQTGYYRVNYE 608
            ||. ||...|.|     ::...|.:.:|.:.|                ||.:|...||:|.|.|:
  Fly   527 PIN-FATTQSPN-----FEDTQVDMFMPPQPQYTVSLEDLNIHVSGRDWIMVNKQHTGFYLVRYD 585

  Fly   609 ESLWALLIQQLTTSPARFEIADRGHLLNDAFALADANQL-SYKIPLDMTAYLAQERDFVPWYVAS 672
            ......:.:||.|:.:.....:|..|..|...|.:.|:: ..::..::..||..|.|.:.|....
  Fly   586 TDNLMAIARQLQTNHSVIHPINRLGLFRDLGPLIEHNEIEQVEVVFELLKYLELEEDVLTWNQLQ 650

  Fly   673 NKLRSLHRSLMFSEGYVSYLTYARSLIA----GVYEEVGWTVDADNHLKNRLRVSILTAACALGV 733
            :.:..|.|:|..:.....:..:.|.|:.    .||.|.|..:..|...:     .||..||:..:
  Fly   651 DTIECLTRNLHGTSSQSLFNEFVRRLVGPTFRRVYVEQGVNLAEDGMFR-----GILEIACSADL 710

  Fly   734 PDCLQQ----ASERFSTFLENPTTRPSPDLREI---VYYYGMQQSTSQSSWDQLFQLFV---AET 788
            |:||:.    |.|.   .::....:...|...|   |...|::..:     ||.||..:   .|.
  Fly   711 PECLEYTRRLAKEH---IIDKIYFKDGSDYHAIIDSVLCMGVRYLS-----DQDFQRIIDMMQEI 767

  Fly   789 DASEKL--KLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQYI----AANPVGEPVVWE 847
            |.:...  .::|.|...::.::|..:|.....:.|.......|..:.|:    .:|....||:|:
  Fly   768 DRASVYYDDIIYALRCTQSHRHLLYYLEGLMGENSTHMVLSEFEDLMYLLYIYKSNLASRPVIWQ 832

  Fly   848 F-------------YREQWPQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQHFFSKYPESGA 899
            :             :.|.:.||......:.|:....:.|..||           |..    :.|.
  Fly   833 YIERNYKVLCRAPNFLEHFKQLAGFVPRHQRSHFERLRQTIAN-----------HMM----QEGL 882

  Fly   900 GANSRLEAVET------IKYNIEWLSRNEADITDWLSGTASPLTKKN 940
            ..|..|..|::      :|....:..:.|..|..||.......|.::
  Fly   883 NTNQTLIEVDSPLVGKKMKITENFQDKFEQQIHKWLLNELPQATSRS 929

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	146/478 (31%)
		ERAP1_C	592..912	CDD:463368	73/359 (20%)
CG5849	NP_650979.1	M1_APN-Q_like	38..492	CDD:341064	146/478 (31%)
		ERAP1_C	569..841	CDD:463368	61/284 (21%)