DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8774 and LTA4H

DIOPT Version :10

Sequence 1:NP_650274.2 Gene:CG8774 / 41635 FlyBaseID:FBgn0038136 Length:942 Species:Drosophila melanogaster
Sequence 2:NP_000886.1 Gene:LTA4H / 4048 HGNCID:6710 Length:611 Species:Homo sapiens


Alignment Length:149 Identity:29/149 - (19%)
Similarity:44/149 - (29%) Gaps:69/149 - (46%)


- Green bases have known domain annotations that are detailed below.


  Fly    46 ASESVKVKFGSSLIRIIDVDEVNQVLTTNLWLEMQWFDYRLMWDPGRWGKIRKLHVPVDQIWI-- 108
            ||.|:.|||.       |.|:..                          .:|::...|.|:.|  
Human    64 ASSSLVVKFA-------DTDKER--------------------------TLRRMQQMVGQLGILT 95

  Fly   109 PDILL-------YNNADGEPHITIMSDAIVYYNGLVVWKPPSIYKSFCSIDIEYFPYDTQTCWMK 166
            |.:.|       |..|..:...|::|.:..|.:..|.:.|       |.|             .:
Human    96 PSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFPP-------CHI-------------QQ 140

  Fly   167 FGGWTYNGFLLDVRQLPTT 185
            .|..:.||       ||.|
Human   141 IGAVSLNG-------LPAT 152

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8774NP_650274.2 M1_APN-Q_like 75..513 CDD:341064 21/120 (18%)
ERAP1_C 592..912 CDD:463368
LTA4HNP_000886.1 leuko_A4_hydro 6..608 CDD:274120 29/149 (19%)
Blue background indicates that the domain is not in the aligned region.

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