Protein Alignment CG8774 and CG7653

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_001356886.1
• Gene: CG7653 / 34935
• FlyBaseID: FBgn0028935
• Length: 710
• Species: Drosophila melanogaster
• Alignment Length: 673
• Identity: 175/673 - (26%)
• Similarity: 318/673 - (47%)
• Gaps: 71/673 - (10%)

  Fly    67 RLPTNLVPTHYELYWHPDLETG---NFTGQQRISIKVVEATNQIILHSYLLDITSVYVL------ 122
            |||..:.|.||::.....||:.   ::||..:|||...:.|||::||...:.|.|..:.
  Fly    43 RLPAKVKPFHYDIRLLTHLESSANHSYTGIVKISIHAQKTTNQVVLHVGRVSIESKKITLFGETS 107

  Fly   123 NREVEKFELEEERQFLIITLTEELAVDASITLGIIFGGQM-KDKLVGLYSSTYLNEAGATRT-IS 185
            |..:.......:|:::::|..:.|.:..|..|.:.||..| .|:..|.:...|:|...:.:. .|
  Fly   108 NYRLRSVRFNNDRKYMVVTFNQSLLMGKSYVLSVEFGRPMTMDQRDGYFIRHYINWKTSEKIWYS 172

  Fly   186 TTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQ---QTESNYLGDYTEAIFETSV 247
            .:.|...:.|...|.||||::||||.:|:.|.. .:.:..||:   ...:..:.||..::.|.:.
  Fly   173 VSHFNRNWIRNTMPSFDEPSLKATFNVTMGHHK-RFQSYGNMKVQAVLPNREIQDYVWSVHEVTP 236

  Fly   248 SMSTYLVCIIVSDF---ASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYY 309
            ::.|:|:...|::|   .||:.::      .....:..|.|..:....||.:....:.|:..:..
  Fly   237 TIPTHLLAFSVNNFNCRYSQAASL------SPVRFRTCAQSADVRATSFAAQMAPQILEFLDRVL 295

  Fly   310 KVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGN 374
            :|..||.|:|...:.||.:.|||::|||.||...||.......:..|......:|||:||.||.|
  Fly   296 QVALPLEKIDQLVVDDFPTEAMENFGLVVYRSKHLLLREDGPMSKEKLQTLELIAHEMAHMWFDN 360

  Fly   375 LVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWG--MLEQFQIVALQPVLLYDAKLSSHPIVQKVE 437
            |:.|..::||||.||.|.|.:...|:.:....|  :|.:::    :..::|::::....:| .:.
  Fly   361 LLGMDSYSDLWLTEGLAGYFKSLAVDHLQSKMGRRILLRYR----ESSMMYESQVGGISLV-PLS 420

  Fly   438 SPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDF------LTEVE 496
            |...:.|  :|..|:|..|:..||...:|.|.|.:.:..::.::.|.::..|.|      .:|.|
  Fly   421 SNASLNA--ETQLYQKATSLTSMLIGFLGNETFYDGLQRHMWQNSFGSSTPDLFWRSLQLASERE 483

  Fly   497 AVVTDL-DIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVP 560
            |..... |:|.:|.|||.|.|||::.|  :.:||....:|....|.:|          .:.|.:|
  Fly   484 ATFDKTWDVKSIMDTWTMQSGYPLVTV--IRNGSEVFLKQGHALNRSS----------SHLWWIP 536

  Fly   561 ITWFADDGSENSFIYD---YDVDSVGIAVPSEV---QWIKLNVNQTGYYRVNYEESLWALLIQQL 619
            :|:..:.||.:..:..   ...:|.||.:...|   |||.||:...|||||||:|..|.||...|
  Fly   537 LTYLIEGGSLSKNLKPKAWLSPNSHGIKLNDIVPRNQWILLNLQAVGYYRVNYDELTWQLLATTL 601

  Fly   620 TTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVP------------WYVAS 672
            ........:.:|..:::|...|.:.:.|::...|::..|:..|.::.|            |.:::
  Fly   602 FNDFRSINVLNRAQIVSDVLFLWNQDLLAWSTALNVLKYIIDEDEYEPLMAFVVGWTNGFWGIST 666

  Fly   673 NKLRSLHRSL-MFSEGYVSYLTY 694
            ....::.:.| :.::.|..:::|
  Fly   667 ESSFNIAKWLGIAAKWYAEFISY 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	122/463 (26%)
		ERAP1_C	592..912	CDD:463368	28/116 (24%)
CG7653	NP_001356886.1	M1_APN-Q_like	52..500	CDD:341064	121/461 (26%)
		ERAP1_C	574..>652	CDD:463368	24/77 (31%)
		dnaA	630..>701	CDD:455861	8/60 (13%)