Protein Alignment CG8774 and LOC3290884

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_061503389.1
• Gene: LOC3290884 / 3290884
• VectorBaseID: AGAMI1_007830
• Length: 956
• Species: Anopheles gambiae
• Alignment Length: 999
• Identity: 285/999 - (28%)
• Similarity: 460/999 - (46%)
• Gaps: 146/999 - (14%)

  Fly     3 LSGYWLQVVLSWAVVAFATATVVVAVQKAQLERDLRDVQDKIDVFEEWSGESRTRMKREDTTDYR 67
            |:.:||.::|       |:|.|.: |:|....||..|             :||          |.
Mosquito     8 LAAFWLPLIL-------ASAPVEI-VEKVSTSRDAHD-------------DSR----------YL 41

  Fly    68 LPTNLVPTHYELYWHPDLETGN-----FTGQQRISIKVVEATNQIILHSYLL------------D 115
            ||....|.:|.|:    |:..|     :.|...|:.:.....|...|:|..|            |
Mosquito    42 LPKVSEPINYNLF----LDITNYDFYSYNGTVEITFRYTGDQNHFYLNSDGLVIATESIKVTGPD 102

  Fly   116 ITSVYVLNREVEKFELEEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNEAG- 179
            .|.|.|.|    ...:||..| :.....:.|.......:.|.|...:..:|.|||.|:|  :||
Mosquito   103 GTDVPVAN----VIYMEEFEQ-IYFGFRDRLQTGEQYKIAISFLNNIGTELKGLYRSSY--KAGN 160

  Fly   180 ATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESNYLGDYTEAIFE 244
            .||.::||.||.||||..|||:|||:.||||.:.:.|.| .|.|:|||....|..:|||||..|:
Mosquito   161 TTRYLATTHFESTYARSVFPCYDEPSYKATFNVKIRHRS-EYRALSNMPAINSVTVGDYTETTFD 224

  Fly   245 TSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEF-G---QAVTEYY 305
            |:..|||||:..::|||.:.|        .|....:.:|...::....:|||| |   :.:..::
Mosquito   225 TTPLMSTYLLAFVISDFKTLS--------HESDRFRVFAAESKVAHTGYALEFLGNSLRTLENFF 281

  Fly   306 IQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQ 370
            .:.|::|    |:|:.||||||.||||:|||:|:||..|:|:...::...||:||..:.||:.|.
Mosquito   282 GRQYQLP----KVDLIAIPDFAMGAMENWGLITFREQYLIYEEGVTTARTKQNIADLITHELTHM 342

  Fly   371 WFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQK 435
            ||||.||.:||..|||:||||||.:|...:.:.|.|.:.:||.:..:...|..|...::..:...
Mosquito   343 WFGNEVTPEWWTYLWLSEGFARYFEYYITSQLEPTWNLWQQFIVNNVHSALSQDCNSNNRMMSYY 407

  Fly   436 VESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVVT 500
            ..:|..:..:||.:.|.|..|||||::.::|.:.|.:::.:||....:..|......|.:|...|
Mosquito   408 ATNPAVLNDLFDYVVYAKSASVIRMIQNVIGFDTFRQSLNDYLRSRSYLTTRPQYLYTSIEKFRT 472

  Fly   501 -DL--DIKKLMLTWTEQMGYPVLNVS-KVADGSFKVTQQRFLSNPASYEEAPSDSAY----GYKW 557
             ||  .::.:..:|....||||:.|| .....:...:|:||.. |...:..|.:..:    .|..
Mosquito   473 VDLPASVEVIFESWANTPGYPVVTVSIDRTTRTLTASQKRFWM-PNEIDTPPQNMLFYIPVNYGS 536

  Fly   558 SVPITWFADDGSENSFIYDYDVDSVGIAVPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTS 622
            :||.:...:|.:...::...| .:..:.:.:.|:|:.:|..|||||||||::..|..||:.|.:.
Mosquito   537 NVPTSTDFEDTTPTFWLTPQD-PTATVTLEAGVEWVVVNKQQTGYYRVNYDDESWHKLIEVLNSD 600

  Fly   623 PARFE----IADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSLM 683
              :||    :.:|..|::|...||.|.::.|.:.|.:..||.:|.:::||..|.|.|..|.|...
Mosquito   601 --QFEDQLPVINRAQLVDDVANLARAGEVGYDVALSLMQYLERETEYIPWATAYNALLYLDRMFS 663

  Fly   684 FSEGYVSYLTYARSLIAGVYEEVGWTVDADNHLKNRLRVSILTAACALGVPDCLQQASERFSTFL 748
            ..|.|..:.|:.|::...:||.:..|...| .:....|.:.:..||..||..||..|..     |
Mosquito   664 SHEEYSRFETFLRTITGCMYENILLTGPMD-QISRLHRGNTVYLACYSGVKKCLDDAHA-----L 722

  Fly   749 ENPTTRPS----PDLREIVYYYGMQQ--STSQSSWDQLFQLFVAETDASEKL----KLMYGLSGV 803
            .|...:.|    |:..:...:..:.:  |.:.::...||:.:|...::.|.|    :.:..:...
Mosquito   723 ANKAVQDSSFTIPEEVQASVFCALHKYPSATLNAQTDLFEKYVTSANSPEDLDMINRFLASVGCA 787

  Fly   804 RNS---QYLFDFLAQASSDESIV---RSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLT----- 857
            ||.   :|....||.......:.   |||.|   :..|..:|.......::..|.:..:|
Mosquito   788 RNETIMEYYLTLLAYNYPGLPVTAGQRSQIY---LGLINGSPGTRQAALQYLYEHFSTVTYLLTS 849

  Fly   858 -----TRFGLNNRNFGRLIAQITANFASSVKLEEVQHFFSKYPESGAGANSRLEAVETIKYNIEW 917
                 |..|  ||...||..::..|.     ::|.:|..:...::.|.|     |:...:.||.|
Mosquito   850 VTPIFTELG--NRINTRLQHEVLKNI-----VDEYRHMLTTAAKAAADA-----ALVKAEQNIRW 902

  Fly   918 LSRNEADITDWL------SGTASP 935
            :.::...||.||      ..||.|
Mosquito   903 IEKHAESITSWLVEQDYEGTTAQP 926

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	154/462 (33%)
		ERAP1_C	592..912	CDD:463368	86/349 (25%)
LOC3290884	XP_061503389.1	None