Protein Alignment CG8774 and LOC3289852

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_554544.4
• Gene: LOC3289852 / 3289852
• VectorBaseID: AGAMI1_005048
• Length: 906
• Species: Anopheles gambiae
• Alignment Length: 961
• Identity: 282/961 - (29%)
• Similarity: 440/961 - (45%)
• Gaps: 147/961 - (15%)

  Fly     8 LQVVLSWAVVAFA----TATVVVAVQKAQ----LERDLRDVQDKIDVFEEWS-GESRTRMKREDT 63
            |.|:|..|:...|    ..||.|:|::.|    |:|      .|:.:.:... .|..:|:    .
Mosquito     8 LSVLLMCALAPGALRAQQPTVTVSVERHQQPGHLDR------SKLHLLKHQKFSERSSRV----A 62

  Fly    64 TDYRLPTNLVPTHY--ELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYVLNR-- 124
            :.||||.:.:|..|  ||..:...|..::.|...|.::|::.|..|:|||....:..|.|.|.
Mosquito    63 SQYRLPNDTIPESYVLELSSNVHAEDFSYGGSVAIRVRVLQTTRSIVLHSLYSKLVKVEVRNANQ 127

  Fly   125 -EVEKFELEEERQFLIITLTEELAVDASI-TLGIIFGGQMKDKLVGLYSSTYLNEAGATRTISTT 187
             .:....:||:.....:|:..:..:...| .|.|:|...::|...|.|.::| |.....|..:.|
Mosquito   128 LNIPISTVEEDPALETLTIRTDHELQRGIYQLTILFENTLRDDFGGFYRTSY-NSGNEVRYSAVT 191

  Fly   188 KFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESNYLGD-YTEAIFETSVSMST 251
            :|:|..||.||||:|||.::|||.|::....|: ...|||....:...|: ..:..|.|:.||.|
Mosquito   192 QFQPVDARTAFPCYDEPGIRATFTISITSGVGT-KVYSNMPIKSTTITGNGLKQTRFHTTPSMPT 255

  Fly   252 YLVCI-IVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVE-FALEFGQAVTEYYIQYYKVPYP 314
            |||.. |.::||  ||.:...|.....:|:..|.....:..: :.|:.|..:.....||:...|.
Mosquito   256 YLVAFAITNNFA--STRLSLRGPPSSINMELIAPPTVTDTAQTYGLDLGGQIIRTVEQYFNQSYD 318

  Fly   315 LTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTMK 379
            |.|||..|:|||...|||:||||.|.|..||||...|:..:|:::..|:.||..||:.|||:|..
Mosquito   319 LPKLDQLAVPDFYFAAMENWGLVIYEERYLLYDELTSTNRDKENVIATVVHEFVHQFLGNLLTPH 383

  Fly   380 WWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPDEITA 444
            ||:||.|:||||.:.:|...:.|.|.....|:|.:.||||.||:|..::..||...||:..:|..
Mosquito   384 WWSDLSLSEGFATFYEYYLSSMVEPSIRFKEKFTVEALQPALLFDCDINVRPISYNVETRADIER 448

  Fly   445 IFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTE-------VEAVV-TD 501
            :||.|||:||||:.||....:|...|.:.:..|:..:: ..:||.|.|.|       .:||: ..
Mosquito   449 MFDIISYQKGGSIFRMFHYALGELTFVKGIRRYISVNK-GRSVTPDILFESLQVAASEDAVLPLS 512

  Fly   502 LDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFAD 566
            ||:..:|..|..|.||||:.|: :::|.....|:.||...:   ...||..    |.:|||:..
Mosquito   513 LDVGTIMRPWIFQSGYPVVTVT-LSNGELTFMQEHFLYRGS---VVTSDRT----WWIPITYHV- 568

  Fly   567 DGSENSFIYDYDVDSVGIAVP---SEVQ---------WIKLNVNQTGYYRVNYEESLWALLIQQL 619
               ..||   ..|.|....:|   |:|.         :|.:|..|||||||||:|:||..||.:|
Mosquito   569 ---HQSF---GTVQSQQFWMPQGTSQVSLEQGDLLDGFILVNPQQTGYYRVNYDENLWIRLITKL 627

  Fly   620 TTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYV--ASNKLRSLHRSL 682
            ::.|:......||.||:|.|.|..:.::...|...:..|...|.|.:||.|  |::.|..|..:|
Mosquito   628 SSDPSIVSSISRGQLLDDCFKLYYSGRVGSNIIYSLLTYAENEIDAIPWTVAFANDNLGVLQGAL 692

  Fly   683 MFSE-GYVSYLTYARSLIAGVYEEVGW-TVDADNHLKNRLRVSILTAACALGVPDCLQQASERFS 745
            :... .:.::..:...|.|.|:..||: .:.:|.|...:||.:::..:|..|..:|..:|..|..
Mosquito   693 VVERMAFEAFSRFVTGLTANVFNAVGFDALPSDEHETQQLRSAVIEWSCRSGSSECRTEALARML 757

  Fly   746 TFLENPTTRPSPDLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLF 810
            ..|..  ..|.|...:...|.|.....|....:.|:....:..|..::|.::..|:...:.|:|.
Mosquito   758 NDLNG--LAPLPMYLKYSVYCGGATIASPDVLETLWASLQSVNDYGQRLNVIEALACSESEQFLD 820

  Fly   811 DFLAQASSDESIVRSQDYFTCVQYIAANPV-GEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQI 874
            |||      :|:      ||       ||: ||          |
Mosquito   821 DFL------DSV------FT-------NPIAGE----------W--------------------- 835

  Fly   875 TANFASSVKLEEVQHFFSKYPESGAGANSRLEAVETIKYNIEWLSRNEADI 925
             ||...:|           |.:|.||..:         || .|::||...|
Mosquito   836 -ANILRAV-----------YQKSAAGYEA---------YN-RWIARNALQI 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	153/454 (34%)
		ERAP1_C	592..912	CDD:463368	80/324 (25%)
LOC3289852	XP_554544.4	None