Protein Alignment CG8774 and CG31445

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_651689.1
• Gene: CG31445 / 326140
• FlyBaseID: FBgn0051445
• Length: 927
• Species: Drosophila melanogaster
• Alignment Length: 914
• Identity: 290/914 - (31%)
• Similarity: 463/914 - (50%)
• Gaps: 77/914 - (8%)

  Fly    66 YRLPTNLVPTHYELYWHPDLETGN---FTGQQRISIKVVEATNQIILHSYLLDITSVYVLNRE-- 125
            |||||.|.|..|.|.....||:.:   |.|..:|.||.::.|..|.|||..|.|....:..|:
  Fly    27 YRLPTALRPQRYYLRILTLLESPDDLRFAGNVQIVIKALQNTRNITLHSKNLTIDESRITLRQIS 91

  Fly   126 --------VEKFELEEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNE-AGAT 181
                    |....:.....:.|....:||.......|.:.|...:..:|.|.|.|:|.:. ...|
  Fly    92 GAGNMDNCVSSTSVNPTHDYYIFHTCKELLAGNVYKLFLPFSADLTPQLFGYYRSSYKDPVTNKT 156

  Fly   182 RTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYH----AVSNMQQTE---SNYLGDYT 239
            |.:|.|:|||:.||:||||||||..||:|.:|:     .||    |:|||...|   ...|.:|.
  Fly   157 RWLSATQFEPSSARKAFPCFDEPGFKASFVVTL-----GYHKQFNALSNMPVREIRPHESLANYI 216

  Fly   240 EAIFETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEY 304
            ...|:.||.||||||...|:||:.:.:|:....:     .:.:|..:.|::.::|.|||..|.:|
  Fly   217 WCEFQESVPMSTYLVAYSVNDFSFKPSTLPNGAL-----FRTWARPNAIDQCDYAAEFGPKVLQY 276

  Fly   305 YIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAH 369
            |.:::.:.|||.|:|..|:|||::||||:||||.|||:.|||.|::||.|:||.:|..:|||:||
  Fly   277 YEEFFGIRYPLPKIDQMAVPDFSAGAMENWGLVKYRESTLLYSPTHSSLADKQDLANVIAHELAH 341

  Fly   370 QWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQ 434
            ||||||||||||.|||||||||.|:...||..::|:|...::..:.||......|:.:|||||.:
  Fly   342 QWFGNLVTMKWWTDLWLNEGFATYVAGLGVQEIYPEWHSRDKGSLTALMTAFRLDSLVSSHPISR 406

  Fly   435 KVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDF---LTEVE 496
            .::...||...||.|||:||.:|:||:...:|.|.|...:..||..:.:.|...::.   ||...
  Fly   407 PIQMVTEIEESFDAISYQKGSAVLRMMHLFMGEESFRTGLREYLKLYAYKNAEQNNLWESLTTAA 471

  Fly   497 ----AVVTDLDIKKLMLTWTEQMGYPVLNVSK-VADGSFKVTQQRFLSNPASYEEAPSDSAYGYK 556
                |:....||..:|.:||.|.|:||||::: .:.|:.::||:|:|.|    .:.|.....|.
  Fly   472 HQNGALPGHYDINTIMDSWTLQTGFPVLNITRDYSTGTAEITQERYLRN----SQIPQADRVGC- 531

  Fly   557 WSVPITWFADDGSENSFIYD-----YDVDSVGIAVPSEV-------QWIKLNVNQTGYYRVNYEE 609
            |.||:::...|  ||.|...     .:..|....||:.:       :|:.||:..:..|:.||:.
  Fly   532 WWVPLSYTTQD--ENDFNNTSPKAWMECSSTDEGVPTTIDHSAGPEEWLILNIQLSTPYKANYDA 594

  Fly   610 SLWALLIQQLTTSPAR-FEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASN 673
            ..|.|||..|.:...: ..:.:|..|::|....|...:..|:..|.:|.||.:|||.:||..|.:
  Fly   595 RNWKLLIDTLNSKDFQSIHVINRAQLIDDVLYFAWTGEQDYETALQVTNYLRRERDLIPWKSALD 659

  Fly   674 KLRSLHRSLMFSEGYVSYLTYARSLIAGVYEEVGWTVDADNHLKNR----LRVSILTAACALGVP 734
            .|:.|:|.|..:..:.|:..|.:.|:..:||.:....|..:.:..:    |:.:::..||...|.
  Fly   660 NLKLLNRILRQTPNFGSFKRYMQKLLTPIYEHLHGMNDTFSLMTQQDEVLLKTTVVNVACQYDVS 724

  Fly   735 DCLQQASERFSTFL--ENP-TTRPSP-DLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLK 795
            ||:.||...|..:.  .|| ...|.| :||..||...:.|.| :..|:.|:..:.....|||:..
  Fly   725 DCVTQAQAYFRRWRAETNPDENHPVPLNLRSTVYCTAISQGT-EEDWNFLWSRYRKSNVASERQT 788

  Fly   796 LMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTRF 860
            ::..|...:....|..::.::...:|.:|.||...|.|.:|:..||..:..:::.|....:...:
  Fly   789 ILSTLGCSKEVWILQRYMEKSFHPKSAIRKQDSSLCFQAVASREVGFLLAKQYFIENVELIHKYY 853

  Fly   861 GLNNRNFGRLIAQITANFASSVKLEEVQHFFSKYPESGAGANSRL-EAVETIKYNIEWLSRNEAD 924
            ....|...||:..::...::...|.:.:.|.:.......|....: :::||:..|::|:
  Fly   854 YPQTRVMSRLLTPLSEQVSTINDLNKFRSFANDSRHFLKGIRQAMQQSLETMLTNVQWM------ 912

  Fly   925 ITDW 928
              ||
  Fly   913 --DW 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	174/465 (37%)
		ERAP1_C	592..912	CDD:463368	80/329 (24%)
CG31445	NP_651689.1	M1_APN-Q_like	37..492	CDD:341064	174/464 (38%)
		ERAP1_C	577..905	CDD:463368	79/328 (24%)