Protein Alignment CG8774 and lnpep

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_021331685.2
• Gene: lnpep / 322814
• ZFINID: ZDB-GENE-030131-1534
• Length: 1025
• Species: Danio rerio
• Alignment Length: 881
• Identity: 292/881 - (33%)
• Similarity: 469/881 - (53%)
• Gaps: 44/881 - (4%)

  Fly    64 TDYRLPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYVLNREVEK 128
            ||.|||.::.|.||.:..||||.:..|.|...|.:.||..|..|:|||..::|..|...::|...
Zfish   174 TDLRLPVSVHPVHYNISLHPDLNSMTFQGNVSIVVLVVHETKNIVLHSSDMNIIKVTFDDKEYRF 238

  Fly   129 FELEEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNEAGATRTISTTKFEPTY 193
            .|.:..:| :.|...|:|. .....|...:...:.:...|.|:|:|::.||..|.::.|:|||..
Zfish   239 LEYKPWQQ-IAIKFPEDLK-KGQYVLKFSYKANLSNSYDGFYNSSYVDTAGTKRVLAATQFEPLA 301

  Fly   194 ARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESNYLGD--YTEAIFETSVSMSTYLVCI 256
            ||:|||||||||.|:||.:.:.. ...|.::|||.:.::..|.:  ..|..||:||.||||||..
Zfish   302 ARKAFPCFDEPAFKSTFVVKMTR-EAKYISLSNMPKIKTTDLNENGLQEDEFESSVKMSTYLVAF 365

  Fly   257 IVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPYPLTKLDMA 321
            ||::|:|.|..|...      ::..||...:.::|.:|||....:.::|..::::.|||:|||:.
Zfish   366 IVAEFSSHSKNVSKT------TVSVYAVPDKKDQVHYALETACKLLKFYNTFFEIEYPLSKLDLV 424

  Fly   322 AIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWL 386
            |||||.:||||:|||:|:|||.||.. :.||..:||.:...:|||:|||||||||||:|||||||
Zfish   425 AIPDFLAGAMENWGLITFRETTLLVG-NQSSRFDKQLVTSVIAHELAHQWFGNLVTMRWWNDLWL 488

  Fly   387 NEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPDEITAIFDTISY 451
            |||||.||||..:..|.||..:..:|..|..: .|..||..||||:...|.:|:::..:||::||
Zfish   489 NEGFATYMQYMSIENVFPDLDIDIEFLNVRFK-ALAKDALNSSHPVSTFVSTPEQVEEMFDSVSY 552

  Fly   452 EKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAV-VTDLDIKKLMLTWTEQM 515
            |||.|::.||...:...:|.:.|..||..:..:||.:.|....:..| ...|::.::|.|||...
Zfish   553 EKGASILLMLNATLRDGEFHKGVIEYLQNYNLSNTESKDLWNSLSQVSKQSLNVSEMMNTWTVHK 617

  Fly   516 GYPVLNVSKVADG-SFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFADDGS---ENSFIYD 576
            |:|::.|.:  :| ...::|:.||.|.   |....||.    |.:|:|:..|..|   ....::.
Zfish   618 GFPLVTVKR--NGPQVTLSQEHFLLNA---ENGTDDSL----WHIPLTYVNDSCSVLRSCKQVFH 673

  Fly   577 YDVDSVGIAVPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLNDAFAL 641
            .......:.:|.:|:|:|.|....|:|.|:|:|..|:.||..|..........|:..|:|:.|||
Zfish   674 LKDKEATLQLPGQVKWLKFNFRSDGFYIVHYDEQGWSDLISALKVDVNVLPSEDKAALINNIFAL 738

  Fly   642 ADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSL-------MFSEGYVSYLTYARSLI 699
            :...::|::..|::..|:..|.:..|...|.::|..::|.|       :.|    |..||..|..
Zfish   739 SRLGKVSFRQVLNLMDYIRNETETAPLTEALSQLGQIYRLLDKRSDLNLAS----SMTTYIESHF 799

  Fly   700 AGVYEEVGWTVDADNHLKNRLRVSILTAACALGVPDCLQQASERFSTFL-ENPTTRPSPDLREIV 763
            ..:.|...|.|:. :..|..||.::|..||||..|:|..||...|..:| .|.|.:...||...|
Zfish   800 GSLMESQSWEVET-SVSKMTLRSALLETACALNRPNCTTQARRLFDQWLASNKTLQIPSDLMRTV 863

  Fly   764 YYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDY 828
            :...   :.:...|.:|...:......:||.|::..|:..::.:.:. ::.|.|.|.|.:::|::
Zfish   864 FKVA---AKTDEGWSKLLGSYKHSIYDTEKRKMLEALASTQDVRKII-WVLQKSLDGSEIQNQEF 924

  Fly   829 FTCVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQHFFSK 893
            ...:..:..:..|....|:|.:|.|.::|.:|.:.:.....:|...|:.|::...|.|||:|||.
Zfish   925 PLVIHTVCRDFAGYLYAWDFMKENWEKITQKFPIGSFAIQSIITSTTSQFSTKTHLAEVQNFFSS 989

  Fly   894 YPESGAGANSRLEAVETIKYNIEWLSRNEADITDWL 929
            ....|:......||:||||:|:.|:.:|...:..||
Zfish   990 LGAKGSQMRIVQEAIETIKHNMRWMEKNLNTLQSWL 1025

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	173/440 (39%)
		ERAP1_C	592..912	CDD:463368	87/327 (27%)
lnpep	XP_021331685.2	None