Protein Alignment CG8774 and CG2111

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Alignment Length: 920
• Identity: 230/920 - (25%)
• Similarity: 399/920 - (43%)
• Gaps: 146/920 - (15%)

  Fly    67 RLPTNLVPTHYELYWHPDLET------GNFTGQQRISIKVVEATNQIILHSYLLDI---TSVYVL 122
            |||..|||..|.:    |:.|      ..|.|...|.::...:|.:|:|:::.|.|   .:|.:.
  Fly    25 RLPKWLVPLSYRV----DIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVTLS 85

  Fly   123 NRE-----VEKFELEEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYL-NEAGAT 181
            ::.     |...:::.:...|.::|...|.|:.:.::.:.|...:::...|.|||.|: :....|
  Fly    86 DKNGNSVPVSSIQMDIKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNTTLT 150

  Fly   182 RTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNM--QQT-ESNYLGDYTEAIF 243
            :.::.|:|||.:||:||||||:|..:..|.|.:.||. .|.|:|||  |:| ....|.||....|
  Fly   151 QWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPY-LYRALSNMPVQRTIRHASLKDYVWTQF 214

  Fly   244 ETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQY 308
            ..|..|.||||..::|.|.....|....   .|..:..:|....:::.|||......:..:|...
  Fly   215 VESHPMQTYLVAFMISKFDRPGFTSSER---SDCPISTWARPDALSQTEFANMVVAPLLSFYEDL 276

  Fly   309 YKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFG 373
            :...|...|:|:.|:|||...:.|:|||..:.|.:||||...||..::|.:|..:|..:.:||||
  Fly   277 FNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAVAMMVVNQWFG 341

  Fly   374 NLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVES 438
            |||::.||:::||...||.|:...||:::.|:|...|:..:.....||.|||.:::..:...|..
  Fly   342 NLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDYDAHVNTDLVTASVPD 406

  Fly   439 PDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVV---- 499
            ...|.|.::.|...|...:..||..::|.|.:..|:..|||.:......:.||...::..|
  Fly   407 ESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDFWDLLQLQVDRNG 471

  Fly   500 ---TDLDIKKLMLTWTEQMGYPVLNVSKVAD-GSFKVTQQRFLSNPA---SYEEAPSDSAYGYKW 557
               ..|:|.::|..|..|.|||::.|::..| .:..|:||||...|.   .:...|.       |
  Fly   472 RLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFITPQFRNRWARNPC-------W 529

  Fly   558 SVPITWFADDGSENSFIYDYDVDSVGIAVPSE------------------VQWIKLNVNQTGYYR 604
            .||:: :.....::|.|..:   |..:..|:.                  ..||..||..|..:|
  Fly   530 WVPLS-YTCPSCQHSEIISF---SRWLTCPTSKPSSKSNTVLLEKLEAEPTDWILFNVQHTAPFR 590

  Fly   605 VNYEESLWALLIQQLTTSPARFEI---ADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFV 666
            |||:...|.||.:.| ..|.:|.:   .:|..|::|.|:||.:..:.|.:.|.:..||..|.:||
  Fly   591 VNYDLRNWQLLNKTL-ADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGYLEHEDEFV 654

  Fly   667 PWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYEEVGWTVDAD--------NHLKNRLRVS 723
            .|.........::.....:..|:.:.||.|.|:...::.|   :.:|        .|     |..
  Fly   655 VWVATEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRV---ISSDLTSSSGNMTH-----RPV 711

  Fly   724 ILTAACALGVPDCLQQASERFSTFLENPTTRPSPDLREIVYYYGMQQSTSQSSWDQLFQLFVAET 788
            |:..||...:|.|:..|...|                       |:.:..:..|     :.:.|.
  Fly   712 IIRLACEYELPACVSLARREF-----------------------MKGTPEKGGW-----MTIRER 748

  Fly   789 DASEKLKLMYGLSGVRNS-QYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQ 852
            :......:.:|..|.|:. :.::.....|:..||::.:   ..|.:.:.|  :...::|.|...
  Fly   749 ETVVCTAVKFGTEGDRDMVESMYKRSNFAAEKESLLTA---LACSRNVFA--LQRVLIWTFESS- 807

  Fly   853 WPQLTTRFGLNNRNFGRLIAQITANFAS--------SVKLEEVQHFFSKYPESGAGANSRLEAVE 909
                    |:..:|..|....:.:|...        ||.::.::::.|         ||..:.|.
  Fly   808 --------GVRKQNARRTFKAVVSNSMGYRLAKKYVSVNMQNIRNYCS---------NSTDKVVN 855

  Fly   910 TIKYNIEWLS 919
            .:...||.||
  Fly   856 LMTPLIECLS 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	132/462 (29%)
		ERAP1_C	592..912	CDD:463368	68/339 (20%)
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	131/461 (28%)
		ERAP1_C	578..897	CDD:463368	72/348 (21%)