Protein Alignment CG8774 and CG31198

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_732654.1
• Gene: CG31198 / 318622
• FlyBaseID: FBgn0051198
• Length: 940
• Species: Drosophila melanogaster
• Alignment Length: 932
• Identity: 278/932 - (29%)
• Similarity: 473/932 - (50%)
• Gaps: 109/932 - (11%)

  Fly    62 DTTDYRLPTNLVPTHYELYWHPD-LET-GN--FTGQQRISIKVV--EATNQIILHS--------- 111
            :..:|||..::.|.:|.:...|. ||| ||  ||....:.|:|:  :.||.|.|||
  Fly    37 ELNEYRLAEHITPVNYNITLRPYLLETDGNKRFTFDGEVWIEVISNQTTNDIYLHSKNLTYSVRE 101

  Fly   112 ------------YLLDITSVYVLNREVEKFELEEERQFLIITLTEELAVDASIT--LGIIFGGQM 162
                        .::.|::....|.:.:           |:.||...|:.|:.|  |..::.|.|
  Fly   102 YWQKPTTEVANPTVIQISATNTTNYDTD-----------IVKLTASTALTANTTYILHFVYTGLM 155

  Fly   163 KDKLVGLYSSTYLNEAGATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNM 227
            :|.:.|.|.|:|:::...|:.:.:|:|:..:||:|||.||||..||||.:|:.. ..::::|||.
  Fly   156 EDDMHGFYRSSYVDDNNVTKWLGSTQFQTHHARRAFPSFDEPQFKATFDVTLKR-HRTFNSVSNT 219

  Fly   228 Q------QTESNYLGDYTEAIFETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSH 286
            :      .||.....|    :::|:..|||||:..|:|:|.::.        .:||.:  ||...
  Fly   220 RLISSYPSTEEGIFSD----VYKTTPKMSTYLLAFIISEFVARK--------DDDFGV--YARPE 270

  Fly   287 QINKVEFALEFGQAVTEYYIQYYKVPY---PLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDP 348
            ...:.::....|..:.|...||....|   ...|:||||||||::||||:|||:||||.:||.|.
  Fly   271 YYAQTQYPYNVGIQILEEMGQYLDKDYYSMGNDKMDMAAIPDFSAGAMENWGLLTYRERSLLVDE 335

  Fly   349 SYSSTANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQ 413
            |.::.|::||||..:|||.||.|||:|||.|||:..|||||||||.||.|...|...|.:.:||.
  Fly   336 SATTLASRQSIAAVVAHEQAHMWFGDLVTCKWWSYTWLNEGFARYFQYFGTAMVEDKWELEKQFV 400

  Fly   414 IVALQPVLLYDAKLSSHPIV-QKVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNY 477
            :..:|.|:..|:..:::|:. :...:|..::.:|::|||.||.:.|||::..:|.::|::::..|
  Fly   401 VDQVQSVMAMDSTNATNPLSDENTYTPAHLSRMFNSISYNKGATFIRMIKHTMGEQQFQKSLQEY 465

  Fly   478 LVKHQFNNTVTDDFLTEVEAVVTDLDI----KKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFL 538
            |.|:::.:::.:..|...:|...:...    |.:..::|||:|||::||: |.:.....||:|||
  Fly   466 LKKYEYQSSLPEYLLGAWQANWPNSSYNESSKDIFKSFTEQVGYPLINVT-VGNSQVSFTQKRFL 529

  Fly   539 SNPASYEEAPSDSAYGYKWSVPITWFADD-----GSENSFIYDYDVDSVGIAVPSEVQWIKLNVN 598
            ..    |...|||:  .|::|||::...:     .:...||...:|.:. :...|.::||.:|:.
  Fly   530 LK----ESDGSDSS--LKYTVPISYTTSETNNFLNTTPKFILKPNVTTT-VQFNSTIKWIVVNIQ 587

  Fly   599 QTGYYRVNYEESLWALLIQQLTTSP-ARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQE 662
            |||||||.|.:..|..:...|.|:. ......:|..:::|.|.||.|..::|.:.||:..||..|
  Fly   588 QTGYYRVTYSDDNWHAIHHALITANWGGIHENNRAQIVDDLFNLARAGYVTYNLTLDVIEYLQTE 652

  Fly   663 RDFVPWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYEEVGWT-VDADNHLKNRLRVSILT 726
            .:::||..|.|....|  ::........:..|.::|....|.::|:. ...|..|...||..||:
  Fly   653 TNYIPWTSAFNGFNYL--TIRLGNDTADFNYYIQTLTNKAYNQLGFNEASNDTALDIYLRTKILS 715

  Fly   727 AACALGVPDCLQQASERFSTFLENPTTRPSPDLREIVYYYGMQQSTSQSSWDQLFQLFVAETDAS 791
            .||..|..||:.||...|.:....|     .::|..||..|:::. .::.:..|:..|..||.|:
  Fly   716 WACRYGSSDCISQAQGYFQSLATVP-----KNIRATVYCVGLREG-GEAEFQALYNKFKNETVAT 774

  Fly   792 EKLKLMYGLSGVRNS---QYLFDFLAQASSDESIVRSQDYFTCVQ--YIAANPVGEPVVWEFYRE 851
            |:..|......|:..   :.:||.:.   |||  :|.||..:.:.  |...|....| |:....:
  Fly   775 EETLLQNSFGCVKTQSLIEKVFDLII---SDE--IRRQDKSSVLATLYTENNENVSP-VFALVTQ 833

  Fly   852 QWPQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQHFFSKYPESGAGANSRLEAVE-TIKYNI 915
            ::.:|....| .......:|:.|.|.|.::.:|.::::|..........:.:.|.|.| |:|.|:
  Fly   834 KYEELAEAMG-GYSAVATVISNIAARFTTNQQLTDLENFNKANGAKFGSSQATLTAAEATVKENL 897

  Fly   916 EWLSRN----EADITDWLSGTA 933
            ||.:..    .:.:.::.||:|
  Fly   898 EWATAKLGVFRSYLANYRSGSA 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	155/480 (32%)
		ERAP1_C	592..912	CDD:463368	86/327 (26%)
CG31198	NP_732654.1	M1_APN-Q_like	50..505	CDD:341064	155/480 (32%)
		ERAP1_C	581..898	CDD:463368	88/331 (27%)