Protein Alignment CG8774 and AC3.5

DIOPT Version :9

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_001256214.1
• Gene: AC3.5 / 179447
• WormBaseID: WBGene00007071
• Length: 1090
• Species: Caenorhabditis elegans
• Alignment Length: 1005
• Identity: 223/1005 - (22%)
• Similarity: 416/1005 - (41%)
• Gaps: 161/1005 - (16%)

  Fly    45 DVFEEWSGESRTRMKREDTTDYRLPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIIL 109
            |:..|...:....:|:....:..||.|:.|..|::...|.:......|...:.:.:.|.||:|:|
 Worm   133 DIVNEEDADENASIKQPTKEELALPKNVQPVWYDVSLSPKVGGNGTMGLAHVKLNIEEPTNKIVL 197

  Fly   110 HSYLLDIT---SVYVLNREVEK------------------------------------------- 128
            ::..::.|   ....|::||.|
 Worm   198 NAKDIEFTRNLEKIQLSKEVTKRAKKSVDSGTNSTSEMPEGSGEEAMATTATTTTTESTTPVSSF 262

  Fly   129 ---------FELEEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNEAGATRTI 184
                     .|.:|..:.:.:||.:||...:::.|.|.|..::.:. .||....|.|..|..:::
 Worm   263 VDTGIKVTNIEFDENLEKVTLTLDQELKKGSTVVLKIPFTSKVSNN-NGLKEYKYKNSEGKEQSM 326

  Fly   185 STTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESNYLGDYTEAIFETSVSM 249
            .||:...:|.|..||.||:.|.||..|||::|..||....:...:|:.:  ||     .:||...
 Worm   327 FTTQPSYSYLRHVFPSFDQEAFKAPAAITLMHSKGSIVVANTGVKTKDD--GD-----AQTSTLN 384

  Fly   250 STYLVCIIVSDF-ASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPY 313
            .......::.|. ||:..|  .:||    :::.:......:..|.:|::.....:......:...
 Worm   385 KVLDPDFVIGDLVASEVNT--TSGI----TIRIWTRPEVKHSTEQSLDYANQAIDAMEHILQSRL 443

  Fly   314 PLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTM 378
            ....||:.|:|.|.:|.......:...|..:||:...:....|..||..:::.||.||||.:...
 Worm   444 ESKSLDIVAVPGFQTGNRVSPSFIVLPEEDILYNEQSNDINQKTRIARMISNRIAAQWFGGITNP 508

  Fly   379 KWWNDLWLNEGFARYMQYKGVNA---VHPD--WGMLEQFQIVALQPVLLYDAKLSSHPI-VQKVE 437
            :.:...||||...|:::.:.:..   ::.|  |       ...::.:|..||..:|.|: |:.|.
 Worm   509 EEFGTFWLNEALPRFLEVEALEKILDINSDDLW-------TYEMEKILERDATATSQPLRVKNVF 566

  Fly   438 SPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVV--- 499
            |..:|..|......:||.:|:||::..||...|.:|:.:::..::......|......|..:
 Worm   567 SSADIAEIDHEFIGKKGAAVLRMIQKSVGVNVFNKAIRSFVSSYRSAYPYDDGLWKSFEKALGGK 631

  Fly   500 ------TDLDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSA-YGYKW 557
                  ..||:.|.:.||.:|:|:|:::|.|:.|.:.:::|:||.::..:.|:....:| |.:.|
 Worm   632 LKGWNNEPLDVAKFVNTWVDQIGFPLVSVEKLDDETVELSQERFKNDHKTKEQFKFRNAKYWFNW 696

  Fly   558 SVPITWFADDGSENSFIYDYDVDSVGIAVPSEVQW--------------IKLNVNQTGYYRVNYE 608
            .||: :....|            .||     .|.|              |.||.:..|.||||||
 Worm   697 EVPL-FLKSSG------------PVG-----NVSWLHEAFRLPLNTSDSIYLNTDSNGVYRVNYE 743

  Fly   609 ESLWALLIQQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASN 673
            |..|..:.:||..|..:.....|..|::|.||||::..|.::..|::|:||..|...|||.:|:.
 Worm   744 EKRWNDIAKQLEKSHGKLSERTRARLISDVFALANSGALPFETALNVTSYLPMETATVPWLIATR 808

  Fly   674 KLRSLHRSLMFSEG-----YVSYLTYARSLIAGVYEEVGWTVD--ADNHLKNRLRVSILTAACAL 731
            ..:.|...|   ||     .::...|.:  |...:||:..:..  :.|:|||||..::|.....:
 Worm   809 IFKKLTERL---EGAPIQDKLNSFIYQK--IHKKFEEISSSPGEASSNYLKNRLYANLLDLMAIV 868

  Fly   732 GVPDCLQQASE----------RFSTFLENPTTRPSPDLREIVYYYGMQQSTSQSSWDQLFQLFVA 786
            ......::.:|          :||....:..:....||||.||..|::.. :.:.::.:.:|...
 Worm   869 KPEKSNEKLNELFVEGFLAPCQFSGNFSSDCSEVPGDLREKVYCNGVEFG-NDTVFETVRELAEK 932

  Fly   787 ETDASEKLKLMYGLSGVRNSQYL----FDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWE 847
            |.|.:||..|...|:..|:.:.|    .|.|...|:...::|..:         :.|||:.:...
 Worm   933 EVDGAEKDLLQNSLACFRDPRALRRLILDNLNSTSTVTLLLRKMN---------SRPVGKEIATN 988

  Fly   848 FYREQWPQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQHFFSKYPESGAGANSRLEAVETIK 912
            :..:.|..:..:...|:......||.......:..:...::.|...:.:|..|..|..:.:|...
 Worm   989 WIIDNWSTVLKKKFKNDPETLNAIADAGIILDNEREKSMIETFMEHHHKSTHGIESLDKKIEEAT 1053

  Fly   913 YNIEWLSRNEADITDWLSGTASPLTKKNQL 942
            .:|.|..:...::.|:|.|......|.:::
 Worm  1054 TDIYWRKQKINELNDYLDGKMKGPAKDDEM 1083

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	Peptidase_M1	67..454	CDD:279741	96/448 (21%)
		M1_APN_2	75..518	CDD:189008	110/513 (21%)
		ERAP1_C	593..910	CDD:288671	81/337 (24%)
AC3.5	NP_001256214.1	Peptidase_M1	156..574	CDD:279741	95/438 (22%)
		GluZincin	165..656	CDD:301352	110/511 (22%)
		ERAP1_C	728..1052	CDD:288671	82/338 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020