Protein Alignment CG8774 and ltah-1.1

DIOPT Version :9

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_001023056.1
• Gene: ltah-1.1 / 178176
• WormBaseID: WBGene00016589
• Length: 609
• Species: Caenorhabditis elegans
• Alignment Length: 635
• Identity: 163/635 - (25%)
• Similarity: 270/635 - (42%)
• Gaps: 140/635 - (22%)

  Fly    75 THYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYV-LNREVEK--FELEEER- 135
            :||.|.|..|.|..:..|...|::.|.:.|.:|:|.:..|.:.||.: ||.|.:|  |.||:.:
 Worm    21 SHYALKWKVDFEKKHIAGDVSITLDVKQDTERIVLDTRDLSVQSVALNLNGEPKKAGFTLEDNQA 85

  Fly   136 --QFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNEAGATRTIS---TTKFEPTY-- 193
              |.|:|| ||.|.......|.|            .|.|:  |.|.|.:.::   ||.....|
 Worm    86 LGQKLVIT-TESLKSGDRPVLEI------------KYESS--NNAAALQFLTAEQTTDRVAPYLF 135

  Fly   194 -------ARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNM-QQTESNYLGDYTEAIFETSVSMS 250
                   ||...||.|.|::|:|:...|..|.|....:|.: |.:..:..|..|...|:..||:.
 Worm   136 SQCQAINARSIVPCMDTPSVKSTYEAEVCVPIGLTCLMSAIGQGSTPSECGKRTIFSFKQPVSIP 200

  Fly   251 TYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPYPL 315
            :||:.|:|.....:..:.:.....|  ..||.|:.::..:.|..|:..:.|..        ||..
 Worm   201 SYLLAIVVGHLERKEISERCAVWAE--PSQAEASFYEFAETEKILKVAEDVAG--------PYVW 255

  Fly   316 TKLDMAAIP-DFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTMK 379
            .:.|:..:| .|..|.||:..|.....|.|         |..:|:...:||||:|.|.|||||..
 Worm   256 GRYDLVVLPATFPFGGMENPCLTFITPTLL---------AGDRSLVNVIAHEISHSWTGNLVTNF 311

  Fly   380 WWNDLWLNEGFARYMQYKGVNAVHPD-WGMLE-QFQ---------IVALQPVLLYDAKLSSHPIV 433
            .|...||||||..:::.|    :|.. :|.|| ||:         :..:..|...|.:.:.  :|
 Worm   312 SWEHFWLNEGFTVFLERK----IHGKMYGELERQFESESGYEEALVRTVNDVFGPDHEYTK--LV 370

  Fly   434 QKVESPDEITAIFDTISYEKGGSVIRMLETLVG-AEKFEEAVTNYLVKHQFNNTVTDDFLTEVEA 497
            |.:.:.|...| |.::.||||.:::..:|..:| ..:||:.:.:|:.|:.:....|:::...:..
 Worm   371 QNLGNADPDDA-FSSVPYEKGSALLFTIEQALGDNSRFEQFLRDYIQKYAYKTVSTEEWKEYLYD 434

  Fly   498 VVTDLDIKKLML------TWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYK 556
            ..||   ||::|      .|..:.|.|              .:.::.|.|.   :|..|.|  .|
 Worm   435 SFTD---KKVILDNIDWNLWLHKAGLP--------------PKPKYDSTPM---QACKDLA--AK 477

  Fly   557 WSVPITWFADDGSE---NSFIYDYDVDSVGIAVPSEVQWIKLNVNQTGY----------YRVNYE 608
            |:.       :|||   :..::....:|..:||...|:     ||:|.:          |:::..
 Worm   478 WTT-------EGSEAPTDGEVFAKMSNSQKLAVLDAVR-----VNKTMFGDRMPALTATYKLDQA 530

  Fly   609 ESL-----WALLIQQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPL 653
            ::.     |.:|..:...||    |.|    .:.||||| ..::.|..|:
 Worm   531 KNAELKFSWLMLGLETKWSP----IVD----ASLAFALA-VGRMKYCKPI 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	Peptidase_M1	67..454	CDD:279741	115/409 (28%)
		M1_APN_2	75..518	CDD:189008	131/480 (27%)
		ERAP1_C	593..910	CDD:288671	17/76 (22%)
ltah-1.1	NP_001023056.1	M1_LTA4H	8..453	CDD:189006	130/475 (27%)
		Leuk-A4-hydro_C	468..608	CDD:312599	29/130 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910