Protein Alignment CG8774 and Y67D8C.9

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_001122826.1
• Gene: Y67D8C.9 / 177088
• WormBaseID: WBGene00022073
• Length: 1144
• Species: Caenorhabditis elegans
• Alignment Length: 1032
• Identity: 249/1032 - (24%)
• Similarity: 397/1032 - (38%)
• Gaps: 267/1032 - (25%)

  Fly    68 LPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSY---LLDITSVYV-LNREVEK 128
            ||..::|.||:|    .|:...|.     :...:.|...|.|.||   ..|....:: .|.::|:
 Worm   182 LPLYILPYHYDL----QLDFSQFD-----THLFIRANISIHLESYGNSTEDEIQFHLGPNIKMER 237

  Fly   129 FELEEE-RQFLIITLTEELAVDASITLGIIFGGQMKDKLVG-------LYSSTYLNE-------- 177
            ..|.:: ::|...|...|    .|..||.|   .::|.|..       .|:.|..:|
 Worm   238 MRLRKDGKKFYAKTFKRE----ESKKLGRI---SLRDPLQKGKYILEMTYNMTICDEDVDGVRCS 295

  Fly   178 ------AGATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTES---- 232
                  :....|..|||||||.||..|||:|||.:||||.|:|.| :..|..:|||...||
 Worm   296 LDNQTNSSLKATSFTTKFEPTLARAFFPCWDEPGVKATFNISVRH-NKKYTVLSNMPPVESHDHK 359

  Fly   233 NYLGDYTEAIFETSVSMSTYLVCIIVSDFAS-QSTTVKANGIGEDFSMQAYATSHQINKVEFALE 296
            ::...:...:|:|:..|||||:...:.:|.. :|.|.:  ||    .:..:.....:..::|.||
 Worm   360 SWEDQFKTTVFQTTPPMSTYLLAFAIGEFVKLESRTER--GI----PVTVWTYPEDVMSMKFTLE 418

  Fly   297 FGQAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQ---- 357
            :...:.:......::||||.|:|:.|..:|..|.||:||||.:...::.|.|..:...|:.
 Worm   419 YAPVIFDRLEDALEIPYPLPKVDLIAARNFHVGGMENWGLVVFEFASIAYTPPITDHVNETVDRM 483

  Fly   358 ----SIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQ 418
                .|...:|||.|||||||||||:.|::|:||||||.:..|:.::...|.....|.:.  :|.
 Worm   484 YNEFRIGKLIAHEAAHQWFGNLVTMRDWSELFLNEGFATFYVYEMMSTERPVTAQFEYYD--SLA 546

  Fly   419 PVLL----YDAKLSSHPIVQKVESPDEITAIF-DTISYEKGGSVIRMLETLVGAEKFEEAVTNYL 478
            .::|    .|.:||   :|:::.:..::.:.| .|..|.||..:||||..||....|:.||..||
 Worm   547 SLILAQSEEDHRLS---LVRELATESQVESSFHPTNLYTKGCVLIRMLRDLVSDFDFKAAVRRYL 608

  Fly   479 VKHQFNNTVTDDFLTEVEAV----VTDLDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQR--- 536
            .|:.:.:...||....:.|.    .....:..::..|....|.|.:.:.:..|.......||
 Worm   609 RKNAYRSVSRDDLFASLPAYADHGAEQEKLSHVLEGWFVNEGIPEITLIRNYDNEMMTISQRKTV 673

  Fly   537 ------FLSN---PASYEEAPSDSAY------------GY------------------------- 555
                  ||.:   .||.....|.||.            ||
 Worm   674 HHEYRSFLKDRKASASVRYRGSRSAEDGSTLFDDALFDGYIEKKKDRRRKHRPIRRKTSTPPSIS 738

  Fly   556 -------------------KWSVPITWFADD--GSENSFIYDYDVD----SVGIAVPSEVQWIKL 595
                               .|::|||:....  .||...|.::.:.    |.|.|..|..|.:.:
 Worm   739 PISRRDELRKPRRVGASQDLWTIPITYMFGSLKTSEGQVIREFWLKNRTVSFGDAEISPNQAVLV 803

  Fly   596 NVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLNDA-FALADANQLSYKIPLDMTAYL 659
            |......|||||:...|.||.:.|..:........|..|:.|| :.|  :|.::..:.|.:..||
 Worm   804 NPEWKYPYRVNYDLLNWKLLARTLHQNHLEINEKSRMQLILDAEYFL--SNSVNPHLYLYLLGYL 866

  Fly   660 AQER---------DFVPWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYEEVGWTVDADNH 715
            |.|.         |.|..::...|...|::::         |.|...:|:.:           :|
 Worm   867 AHETKMEVMLFGIDAVYKFIDVYKATQLNKAI---------LVYFEPVISQM-----------DH 911

  Fly   716 LKNRLRVSILTAA----------------CALGVPDCLQQASERFSTFLENPTTRPSPDLREIVY 764
            |.|..:|...||:                ||.|:..|...
 Worm   912 LLNESQVDAETASLWLVRPERLAKLYQMRCAAGLSSCKND------------------------- 951

  Fly   765 YYGMQQSTSQSSWDQ---------LFQLFVAETDASEKLKLMYGL-------SGVRNSQYLFDFL 813
            ||..:.|.|...|.:         ..|||   |:..:::|.:..|       ||.:.:  |...|
 Worm   952 YYTQRWSRSPDEWTEDVHKQVTAVCHQLF---TNTPDEVKTVQDLLDSRLQSSGAKWA--LTVQL 1011

  Fly   814 AQASSDESIVRSQ-----DYFTCVQYIAA---------NPVGEPVVW-EFYREQWPQLTTRFGLN 863
            |..|.|:.::|..     .....|.|.:|         ||.....:| |..:....:.|..|..|
 Worm  1012 AACSHDQKLLRRTARAIVSTKNAVVYASALQSDFSLHYNPTFRKYLWAEIAKMSTFEKTALFSTN 1076

  Fly   864 NRNFGRLIAQITANFASSVK-LEEVQHFFSKYPESGAGANSRLEAVETIKYNIEWLS 919
            :.:    |...:.....||| ::|:|.........|...:...|.:|  :| :.|:|
 Worm  1077 STD----ILPASRILLHSVKTIDELQQIRGLLTNWGPLLSLHFEYLE--RY-LLWVS 1126

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	141/485 (29%)
		ERAP1_C	592..912	CDD:463368	76/377 (20%)
Y67D8C.9	NP_001122826.1	M1_APN-Q_like	190..645	CDD:341064	140/482 (29%)