Protein Alignment CG8774 and Y53F4B.20

DIOPT Version :9

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_497105.3
• Gene: Y53F4B.20 / 175160
• WormBaseID: WBGene00013166
• Length: 694
• Species: Caenorhabditis elegans
• Alignment Length: 638
• Identity: 144/638 - (22%)
• Similarity: 257/638 - (40%)
• Gaps: 136/638 - (21%)

  Fly    64 TDYRLPTNLVPTHYELYWH--------PDLETGNFTGQQRISIKVVEATNQIILHS-YLLDITSV 119
            :|.|||..|.|..|:|...        ||:..  |||:   .:...|...||...| ::.|.||
 Worm    28 SDDRLPPILKPLSYDLQLQLPLSEVSDPDVPL--FTGR---CVMHFEINQQIGPESAFISDSTS- 86

  Fly   120 YVLNREVEKFEL--------------EEERQFLIITLTEELAVDASITLGIIFGGQMK------D 164
               ||...||::              ..|.:...:.||:: :::.|:...::|.|:..      .
 Worm    87 ---NRARIKFDIIMLDHFENVSLVMNGHELEIFNVQLTDD-SMELSVDQPVLFPGRYTLTIHRYK 147

  Fly   165 KLVGLYSSTYLNEAGATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQ 229
            .|:|  |:.|..:||......:..| |..|...||.:.....|.||:||:|||.|:....|...:
 Worm   148 GLIG--SAIYYRDAGEHAVFGSNLF-PNRAPAVFPSYLASTEKVTFSITMVHPVGTLALTSGSNE 209

  Fly   230 TESNYLGD-YTEAIFETSVSMSTYLVCIIV---------SDFASQSTTVKANGIGEDFSMQAYAT 284
            .....:.: :....|.|:.|::..::|.::         |.:...:.:|..|    .|.:|...|
 Worm   210 GAPRKIDENWQMTTFSTTPSITPSMLCFLLLPHEYTHIESTYTGVNISVHYN----RFRVQKEQT 270

  Fly   285 SHQINKVEFALEFGQAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPS 349
            .|.::.....|...:.:....|       |:.|:|:..:.:.:|.|.  :|.:...|.. .:...
 Worm   271 KHLLHTATQVLALLKDIFSSLI-------PVPKIDIITMNEVSSTAC--FGSIVVSEVQ-FFSAD 325

  Fly   350 YSSTANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQI 414
            |   ||:..:   ||..:|.||.|....:...::|.|.|....::..|.:..:..|    |..::
 Worm   326 Y---ANQVKM---LATWLAKQWIGGYAAISEGSELCLQEDLVAFIADKVIKRMTND----EFTRL 380

  Fly   415 VALQPVLLYDAKLSSHPIVQKVESPDEITAIFDTISYEKGGSVIRMLETLVGAE----KFEEAVT 475
            ..|..:.|.:...::...::..|.|:|. .||:.... ||.:::..:|:|:|.:    |..|.:.
 Worm   381 GHLAKIYLSETIFTAGDTLKLDEHPNEF-EIFEKCGL-KGVAMLESIESLIGEKSMISKINEMIY 443

  Fly   476 N-----YLVKHQF---NNTVTDDFLTEVEAVVTDLDIKKLMLTWTEQMGYPVLNVSKVADGSFKV 532
            |     |..:..:   |:||.:           |:.:.:|:..|.|..|.|.:||.::|: |.|:
 Worm   444 NSKKGSYSSRTLYGLLNSTVDE-----------DIYVSQLLHYWHEHGGLPYMNVDRLAN-SIKI 496

  Fly   533 TQ---QRFLSNPA-SYEEAPSDSAYGYKWSVPITW---------FADDGSENSFIYDYDVDSVGI 584
            ||   ...:.|.| ::|..|       .|.:|:.:         ....|...|.|.|      |:
 Worm   497 TQNGSNMTVKNGAGTWERMP-------LWPLPLKFTEFKLPIQIMVSHGIHLSPIRD------GL 548

  Fly   585 AVPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLND 637
                    |..|:..|.||||||:...|..:...||.:...:.:.:|..|::|
 Worm   549 --------IFSNLGFTNYYRVNYDIDTWREIKTVLTENATSYTLRERFQLVSD 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	Peptidase_M1	67..454	CDD:279741	92/425 (22%)
		M1_APN_2	75..518	CDD:189008	104/493 (21%)
		ERAP1_C	593..910	CDD:288671	15/45 (33%)
Y53F4B.20	NP_497105.3	GluZincin	39..>300	CDD:301352	61/284 (21%)
		ERAP1_C	552..>593	CDD:288671	13/40 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910