Protein Alignment CG8774 and LOC1279320

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_319027.5
• Gene: LOC1279320 / 1279320
• VectorBaseID: AGAMI1_002693
• Length: 646
• Species: Anopheles gambiae
• Alignment Length: 736
• Identity: 162/736 - (22%)
• Similarity: 276/736 - (37%)
• Gaps: 174/736 - (23%)

  Fly    54 SRT-RMKREDTTDYRLPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEA-TNQIILHSYLLDI 116
            :|| |:...|.:.|.....|:..|.:|.|..:.:....:|...:..|:.:. ..::.|....|.:
Mosquito    28 ARTMRLSPLDPSSYSNAQELIIRHVDLDWTVNFDKSTISGTATLHFKLTKKDLEEVFLDVSDLTV 92

  Fly   117 TSVYVLNREVE---KFELEEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNEA 178
            :||...:...|   .|::....:.:...||..|....:..|.::...:...|...|...|.....
Mosquito    93 SSVAAKSNAGEVPLDFDIGGTIENIGSKLTIYLPTKTNDELTLVIAYETSPKASALQWLTPEQTF 157

  Fly   179 GATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPS-----------GSYHAVSNMQQTES 232
            |.......::.:..:||...||.|.||:|.|:..|:.||.           .|...||..||
Mosquito   158 GKKHPYLFSQCQAIHARSILPCQDTPAVKFTYNATLRHPKEVTGLMSAIKVDSEPGVSKFQQ--- 219

  Fly   233 NYLGDYTEAIFETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEF 297
                         ...:.:||:.|:|....|:.       ||...|:  :|...||:  |.|.||
Mosquito   220 -------------KTPIPSYLLAIVVGALVSKP-------IGPISSV--WAEQEQID--EAAEEF 260

  Fly   298 GQAVTEYYIQYYKV--PYPLTKLDMAAI-PDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSI 359
            .| ..::..:..::  ||...:.|:..: |.|..|.||:..|.....|.|         |..:|:
Mosquito   261 SQ-TADFIAKAEEICGPYVWERYDLLVMPPSFPFGGMENPCLTFVTPTLL---------AGDKSL 315

  Fly   360 AGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGV-----------NAVHPDWGMLEQFQ 413
            |..:||||||.|.|||||.:.:...||||||..:::.|.|           :|:|   |:.|...
Mosquito   316 ATVVAHEIAHSWTGNLVTNRNFEHFWLNEGFTVFVEGKIVGRLSGNASRDFHALH---GLSELSD 377

  Fly   414 IVALQPVLLYDAKLSSHPIVQKVE-SPDEITAIFDTISYEKGGSVIRMLETLVGA-EKFEEAVTN 476
            .:..|   |.|....:..:|...| .||:   .|.|:.|.||.:.:|.||.|:|. .|||.....
Mosquito   378 CIKTQ---LADTPELTKLVVDLSECGPDD---AFSTVPYIKGSTFLRYLEDLLGGPSKFEPFFRA 436

  Fly   477 YLVKHQFNNTVTDDFLTEVEAVVTDLDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNP 541
            ||.:.::.:.:|:||             |:::..|..:            |.:.:|..:|.
Mosquito   437 YLDRFKYQSVLTNDF-------------KQMLYEWFRE------------DPNNEVLLERI---- 472

  Fly   542 ASYEEAPSDSAYGYKWSVPITWFADDGSENSFIYDYDVDSVGIAVPSEVQWIKLNVN-------- 598
                          .|.:   |...:|.. ..|..||...:...:.....|.:.:::
Mosquito   473 --------------NWDL---WLFGEGMP-PVIPSYDRSMLEACLAHATLWAENDLDTIKNSPLV 519

  Fly   599 QTGYYRVNYEESLWALL----IQQLTTSPARFEIADRGHLLNDAFALADAN--QLSYKIPLDMTA 657
            :.....|...|.|..||    |..||        |::..||.:.:..:...  :|.::
Mosquito   520 KQSLVSVQLIEFLAQLLEKKKIVDLT--------AEKVALLGETYGFSTTKNAELRFR------- 569

  Fly   658 YLAQERDFVPWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYEEVG-W------TVDADNH 715
                   ||..::.:..:..:...|.|:..     .:....:..||:|:| |      .::..|.
Mosquito   570 -------FVRLFIRARLIEKMDEILAFANS-----NFRMKFVRPVYKELGAWPQARPIAIENYNR 622

  Fly   716 LKNR-LRVSILTAACALGVPD 735
            :|:: :.|...|.|..||:.|
Mosquito   623 VKDQMMTVCAYTVAKDLGISD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	117/468 (25%)
		ERAP1_C	592..912	CDD:463368	30/166 (18%)
LOC1279320	XP_319027.5	None