Protein Alignment CG8774 and LOC1278754

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_318379.6
• Gene: LOC1278754 / 1278754
• VectorBaseID: AGAMI1_000623
• Length: 880
• Species: Anopheles gambiae
• Alignment Length: 916
• Identity: 256/916 - (27%)
• Similarity: 413/916 - (45%)
• Gaps: 183/916 - (19%)

  Fly     8 LQVVLSWAVVAFATATVVVAVQKAQLERDLRDVQDKIDVFEEWSGESRTRMKREDTTDYRLPTNL 72
            :::|:.|.|:......:|..|                                  |.:.||..|.
Mosquito     1 MRIVMLWLVLCSVYLVIVPVV----------------------------------TANGRLSNNT 31

  Fly    73 VPTHYELYWHPDLE-TG------NFTGQQRISIKVVEATNQIILHSYLLDITSVYVLN-REVEKF 129
            :|.||:|:    || ||      .:.|...|.|.:|..||:::||:....:.|:.:.. |:.|..
Mosquito    32 LPLHYDLH----LEATGLGLHDYTYRGNVSIRIAIVSDTNEVVLHNVGNRLKSICLRRCRDGEAI 92

  Fly   130 E---LEEERQFLIITL-TEEL---AVDASITLGIIFGGQMKDKLVGLYSSTYLNEAGATRTISTT 187
            .   ||.|....::.: |:.:   |.|..|||.|:|...:.:..:|.|.:.|.........::||
Mosquito    93 SHQLLESEPASELLRIRTDRILRRADDQVITLTIVFHNTLGEDRMGFYRTQYRGAKRIPMAVATT 157

  Fly   188 KFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESNYLGDYTEAI-FETSVSMST 251
            .|:|:|||.||||||||..|.||.||:| .:||:...||.......:|.|..:|: ||.:..|.|
Mosquito   158 HFQPSYARLAFPCFDEPGFKTTFQITIV-ANGSHLVASNAPIATVTWLQDGHKAVRFERTPPMQT 221

  Fly   252 YLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPYPLT 316
            |||..::::|.|.. ||..:|:    .:...|.......::|:|:....:.....:|......|.
Mosquito   222 YLVTFLIANFTSVH-TVSPSGV----EIGILAPPKDEKSLQFSLQAATTLLSSLEEYTGQSLGLQ 281

  Fly   317 KLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTMKWW 381
            |||..|||.|.: |||:||||.|.|..|:...........|::. |:.||.|||.|||||...||
Mosquito   282 KLDHVAIPRFGN-AMENWGLVAYDEQFLVLSAKAHRLQRAQAVL-TIGHETAHQLFGNLVGPAWW 344

  Fly   382 NDLWLNEGFARYMQ-YKGVNAVHPDWGMLEQ-FQIVALQPVLLYDAKLSSHPIVQKVESPD--EI 442
            :.|||:||||.|.: ..|.:| :|:...||: |.:..:.|.|:.|| ...||:..:..|.:  ||
Mosquito   345 SYLWLSEGFATYFELLLGADA-YPELLPLEESFAVRHMHPALMADA-YEQHPLTVEPLSANTPEI 407

  Fly   443 TAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDD------FLTEVEAVVTD 501
            ..:||||:|.|.|.::||:...:|.|.|:..|.|||.:|: |..||.:      |:.:.:...|
Mosquito   408 ETLFDTITYSKAGCILRMINCSIGEEAFQAGVQNYLEQHR-NGIVTPEDLYASFFVQQRKDTPT- 470

  Fly   502 LDIKKLMLTWTEQMGYPVLNVSKVADGSF-KVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFA 565
              ::::..:|.::.||||:.|.:: :||| :..|||:.:...:.::..|      :|.:|||::.
Mosquito   471 --VEQMFRSWVDKPGYPVVTVERL-NGSFVRFRQQRYHNQEVTIQDITS------RWFIPITYYT 526

  Fly   566 DDGSENSFIYDYDVDSVGIAVPSEVQWIK-------------------LNVNQTGYYRVNYEESL 611
                 ||.:..|:.        ....|:|                   :|..|.|:|||.|:|..
Mosquito   527 -----NSSLGQYEY--------QPAFWMKETDQELVLQLKMNTQDVLVVNPRQIGFYRVEYDERG 578

  Fly   612 WALLIQQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYV--ASNK 674
            |:.::..|||.|:..:    ..|::|||.||.|..:.|::.|:|...||...|.|||.:  |...
Mosquito   579 WSSIVDNLTTLPSIMQ----AKLIDDAFVLARAGLVGYELCLEMLQELATSPDPVPWLIAMAEEN 639

  Fly   675 LRSLHRSLMFSE------GYVSYL-----TYARSLIAGVYEEVG---WTVDADNHLKNRLRVSIL 725
            :..|.|.|..:|      |:|..:     ...|:|:.....:|.   |:..|.:.::::...||.
Mosquito   640 IGYLQRVLQSAEFDRFLTGFVGEMFDLAGNVGRTLLQSQALDVAYDWWSRLAASFIESKRESSIR 704

  Fly   726 TAACALGVPDCLQQASERFSTFLENPTTRPSPDLREIVYYYGMQQSTSQSSWDQLF-QLFVAETD 789
            ..||   :|..:|:..:..        ..|...:||                 :|| :|......
Mosquito   705 PRAC---LPTPVQEVVQAL--------VSPDDHVRE-----------------RLFVRLKCLPKQ 741

  Fly   790 ASEKLKLMYGLSGVRNSQY-----LFDFLAQASSDESIVRSQD---YFTCVQYIAANPVGE--PV 844
            ::|...|:..|..:|.:..     ||..|      ||:::|..   ....||::::.|..|  ||
Mosquito   742 SNEPSVLLLALERIRAANLLTPGKLFAVL------ESLIKSDPGRFLPPSVQFLSSVPPEEAGPV 800

  Fly   845 VWEFYR 850
            ...|.|
Mosquito   801 ADRFQR 806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	154/463 (33%)
		ERAP1_C	592..912	CDD:463368	73/305 (24%)
LOC1278754	XP_318379.6	None