Protein Alignment CG8774 and LOC1278415

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_318000.5
• Gene: LOC1278415 / 1278415
• VectorBaseID: AGAMI1_009252
• Length: 1020
• Species: Anopheles gambiae
• Alignment Length: 923
• Identity: 278/923 - (30%)
• Similarity: 468/923 - (50%)
• Gaps: 79/923 - (8%)

  Fly    66 YRLPTNLVPTHYELYWHPDLETG--NFTGQQRISIKVVEATNQIILHSYLLDITSVYVLNRE--- 125
            |||||..:|.||:|:...::...  .|||...|.::||:||:::::|:..|.::|..|.:..
Mosquito    63 YRLPTTSIPIHYDLHLRTEIHRNERTFTGTVGIQLQVVQATDKLVMHNRGLVMSSAKVSSLPNGV 127

  Fly   126 ------VEKFELEEERQFLIITLTEELAVD-ASITLGIIFGGQMKDKLVGLYSSTYLNEAGATRT 183
                  :...:...:..|..||.|....:. .:..|.:.|.|::.....|.|.|:|:.:.|..|.
Mosquito   128 TGAPTLIGDVQYSTDTTFEHITFTSPTILQPGTYLLEVAFQGRLATNDDGFYVSSYVADNGERRY 192

  Fly   184 ISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNM-QQTESNYLGDYTEAIFETSV 247
            ::||:||.|.||.||||:|||.:||||.:::.| |.||.|:||| |:|.::...|.....||.:.
Mosquito   193 LATTQFESTSARMAFPCYDEPGLKATFTVSITH-SRSYKAISNMPQKTFTDIETDMRTTFFEKTP 256

  Fly   248 SMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVP 312
            :|||||:..:|.||     .::.:|     :.:.|...:.:|:..||||.|..:.:....:..:|
Mosquito   257 AMSTYLLAFVVCDF-----QIRLSG-----AQRVYVRPNALNEATFALEAGVKILKVLDDHLGIP 311

  Fly   313 YP--LTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNL 375
            |.  :.|||..||||||:||||:||||||||.|||::|:.|:...|.::|.|:|||.||||||||
Mosquito   312 YDTYMPKLDQIAIPDFAAGAMENWGLVTYREQALLFNPAVSTYRGKTNVATTIAHEYAHQWFGNL 376

  Fly   376 VTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPD 440
            |:.:||..:|||||||...::..::..:|.....|.|....:|..:..|.:.|:.|:.....:|.
Mosquito   377 VSPEWWEYIWLNEGFATLYEFYALDMAYPGQEYWELFNQQVIQYAMGQDGQASTRPMNWNAATPG 441

  Fly   441 EITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVV------ 499
            ||:|:||.::|:|.|||:.|:..::|.:.::..:..||........|.:.....:::.:
Mosquito   442 EISALFDRVAYDKSGSVLNMMRHVLGDDNWKAGLKAYLTDRALQGAVDEQLYAGLQSAIEGKGVL 506

  Fly   500 -TDLDIKKLMLTWTEQMGYPVLNVSKVAD-GSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPIT 562
             ..:.:.::|.|||.:.|||||||.:..| |...::|:||.::    ...|:.:.    |.:|..
Mosquito   507 PNGVTVGQIMRTWTNEAGYPVLNVRRSYDTGDVIISQERFYND----RNVPNTNI----WMIPYN 563

  Fly   563 WFADDGSENSFIYDYD-----VDSVGIAVPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTS 622
            :.....::.:...|:.     ...:...||:. :||..|..|.|||||||:|..|.|:...|..:
Mosquito   564 YVHQAKADFNEFDDFQWLATKAARIETTVPAN-EWIVFNKQQVGYYRVNYDERNWELITNALHEN 627

  Fly   623 PARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSLMFSEG 687
            .|.....:|..|::||:.||.:.:|..::.|....||..||::.||..|:..|...:..|..:..
Mosquito   628 WASIHRLNRAQLIDDAYWLARSGRLDLRVALRFMTYLRNEREYAPWTAANVALTYFNNRLRGTAE 692

  Fly   688 YVSYLTYARSLIAGVYEEVGWTVDA----DNHLKNRLRVSILTAACALGVPDCLQQASERFSTFL 748
            |.::|.:..:||..:|..:  |:||    |..|...|..:|.|.||::|..|||.:.:.....
Mosquito   693 YHNFLIFVDALIEDIYSLL--TIDAVSPDDTLLHKYLVQTISTWACSMGYTDCLMKTAALLKA-- 753

  Fly   749 ENPTTRPS--PDLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFD 811
            |...|.|:  ||:..:.|.||| :|..:|.:..|::..:...:.:|:..|:..|....|.::|..
Mosquito   754 EASGTGPAVHPDIASVTYCYGM-RSALESEFQYLYRKMMNSKNLAERTMLIDSLGCSNNKEFLKA 817

  Fly   812 FLAQA----SSDESIVRSQDYFTCVQYI-AANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLI 871
            ||..|    :..|...|:.:....||.| :....|...:.||..:  |.|...| ::..:...|.
Mosquito   818 FLTTALGSGTGVEINYRADERRRVVQAIYSGGRTGVDALIEFLMD--PALVNEF-VSTLSTSTLN 879

  Fly   872 AQITANFASSVKLEEVQHFFSKYPESGAGANSRLEA--VETIKYNIEWLSRNEADITD------- 927
            :.::|..:.:..:||:....:.....|:..||:..|  ..|.:.|::|::..|..:..
Mosquito   880 SALSAIASRTNNVEEMNKLNALITALGSRVNSQTAANLRTTAQANLDWVNGFEGLMLSNFLAEFA 944

  Fly   928 ---WLSGTASPLT 937
               .|:.||:|.|
Mosquito   945 AETLLTTTAAPGT 957

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	153/459 (33%)
		ERAP1_C	592..912	CDD:463368	92/332 (28%)
LOC1278415	XP_318000.5	None