Protein Alignment CG8774 and LOC1277402

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_061507132.1
• Gene: LOC1277402 / 1277402
• VectorBaseID: AGAMI1_008618
• Length: 979
• Species: Anopheles gambiae
• Alignment Length: 928
• Identity: 307/928 - (33%)
• Similarity: 470/928 - (50%)
• Gaps: 96/928 - (10%)

  Fly    66 YRLPTNLVPTHYEL--YWHPDLETG-NFTGQQRISIKVVEATNQIILHSYLLDITSVYVLNRE-- 125
            ||||.::.|.||.|  |.|...|.| .|.||..:.:...|.|..|:|||..|.:....:..||
Mosquito    56 YRLPKSITPEHYNLRVYTHLGDERGFIFYGQVAMRLICHEDTENIVLHSKNLTLPEQGISLRELG 120

  Fly   126 -----------VEKFELEEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNEAG 179
                       ::..:..:|..|:|:.:...|.......|.:.|...:...|:|.|.|:|:::|.
Mosquito   121 SAGQQNGSAIAIKSVQYAKEHDFVILNVATVLRKGNRYELVVPFESALGTGLLGYYRSSYVDKAS 185

  Fly   180 ATRT-ISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTES---NYLGDYTE 240
            ..:. ::.|:||||||||||||||||.|||||.|.:.|.. .|.|:|||....|   :.:..:..
Mosquito   186 KQKIWLAVTQFEPTYARQAFPCFDEPEMKATFDIALAHDE-RYVALSNMPVNSSAPVDGMPGWVM 249

  Fly   241 AIFETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYY 305
            .:|.|:|.||||||...|:||..:.......|   |...:.:|....|.:|::|.|.|..||.:|
Mosquito   250 DVFGTTVPMSTYLVAYTVNDFEYREAMAAEEG---DVLFKIWARRDAIEQVDYAREIGPKVTRFY 311

  Fly   306 IQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQ 370
            ..|::..:||.|:||.|||||||||||:|||:|||||||||.|:.|:.:||..:|..:|||:|||
Mosquito   312 EDYFQQKFPLPKIDMIAIPDFASGAMENWGLITYRETALLYHPNVSTASNKHRVASVIAHELAHQ 376

  Fly   371 WFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQK 435
            ||||||||:||.|||||||||.|:...||:.:||:|..||:..:.....:..:||..|||||..:
Mosquito   377 WFGNLVTMRWWTDLWLNEGFATYVASLGVDYLHPEWHSLEEESVSNTLDIFKFDALQSSHPISVE 441

  Fly   436 VESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDF---LTE--- 494
            :..|::|:.|||.||||||..||||:...:..|.|.:.|..||.:|.:.|...|:.   |||
Mosquito   442 IGHPNQISQIFDAISYEKGSIVIRMMHLFLDEETFRDGVGRYLRRHAYGNAEQDNLWAALTEEAH 506

  Fly   495 VEAVVTD-LDIKKLMLTWTEQMGYPVLNVSKVAD-GSFKVTQQRFLSNPASYEEAPSDSAYGYKW 557
            ...|:.| :|:||:|.:||.|.|||::.|::..| .:.:|||.||:|:    :..|..:...|.|
Mosquito   507 ANGVLPDHIDVKKVMDSWTLQTGYPIITVTRNYDANTAEVTQMRFISS----DVRPDSNVTDYCW 567

  Fly   558 SVPIT----------------WFADDG-------SENSFIYDYDVDSVGIAVPSEVQWIKLNVNQ 599
            .:|:|                |.|..|       .|...:.|         :|...||:..||..
Mosquito   568 WIPLTYTTAKQIDFNDTLPKAWMACSGEPKGSHQQEAKLLED---------LPDGDQWVIFNVEL 623

  Fly   600 TGYYRVNYEESLWALLIQQLTTSPARFEIA--DRGHLLNDAFALADANQLSYKIPLDMTAYLAQE 662
            .|.|:|.|:...:.|:|.|| ..|...||.  :|..|::||..||...|.:|.|...|..||.||
Mosquito   624 AGLYKVRYDRRNYQLIIAQL-NGPRFGEIGLLNRAQLIDDAMDLAWTGQQNYGIAFAMLNYLRQE 687

  Fly   663 RDFVPWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYEEVGWTVDADN-------HLKNRL 720
            ..::||..|...|.:::|.|..:..|..:.:|.:.::..:||:    :|..|       .|....
Mosquito   688 TQYIPWKSALTNLNNINRILKRTPLYGVFRSYVQYILEPIYEQ----LDIFNGSRATTERLDGIK 748

  Fly   721 RVSILTA-ACALGVPDCLQQASERFSTFLEN---PTTRPSP-DLREIVYYYGMQQSTSQSSWDQL 780
            :::::.: ||...|.||:.::.|.|:.::..   .|..|.| :||.:||...:::. .::.|..|
Mosquito   749 QITLIASWACRFEVGDCVNRSVELFARWMNESSPDTDNPVPVNLRPVVYCNAIRRG-DEAQWHFL 812

  Fly   781 FQLFVAETDASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVV 845
            :..::.....:||:.::..|:..|..:.:..||..:.:..|.||.||.......::.|..|....
Mosquito   813 WLRYLQSNVGAEKIMIIGSLACTREVRLVERFLQWSLNSTSGVRKQDATILFSGVSRNDAGFAAA 877

  Fly   846 WEFYREQWPQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQHFFSK----YPESGAGANSRLE 906
            .:|:.|:...:......:.....|.|..:.....||.:|:|:.....:    :.::..|....||
Mosquito   878 KKFFLERADDIYNYLSPDTSRLSRYIKPLAEQMFSSEELQELTDLIEQKAPIFEKANQGVKQALE 942

  Fly   907 AVET----IKYNIEWLSR 920
            ..:|    .|.||:.:.|
Mosquito   943 TAQTNNRWSKVNIDKMER 960

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	191/464 (41%)
		ERAP1_C	592..912	CDD:463368	82/341 (24%)
LOC1277402	XP_061507132.1	None