Protein Alignment CG8774 and Psa

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_556379.4
• Gene: Psa / 1276400
• VectorBaseID: AGAMI1_004070
• Length: 1040
• Species: Anopheles gambiae
• Alignment Length: 968
• Identity: 324/968 - (33%)
• Similarity: 481/968 - (49%)
• Gaps: 93/968 - (9%)

  Fly     4 SGYWLQVV--LSWAVVAFATATVVVAVQKAQLERDLRDVQ-DKIDVFEEWSGESRTRMKREDTTD 65
            ||.|..||  :::.....:..||....::.|......... |..||.|      .:..|...||.
Mosquito   116 SGVWSAVVRPVAYGCDGNSARTVSCCTRETQRRYSSTSATIDGSDVCE------TSEYKMSATTG 174

  Fly    66 ----YRLPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYV----- 121
                .|||||:||.||.|...|:|....|.|...:.:||||||::|.|::..|.:.:..|
Mosquito   175 KPKFQRLPTNVVPEHYRLTLKPNLTALTFEGNTAVELKVVEATDRITLNALDLKLGTATVSFGDQ 239

  Fly   122 -LNREVEKFELEEERQFLIITLTEELAVDASI-----TLGIIFGGQMKDKLVGLYSSTYLNEAGA 180
             |..:..:|:..:|        |......|.|     ||.:.|.|::.||:.|.|.|.|.:..|.
Mosquito   240 QLTAQDIQFDAGQE--------TACFVFGAEIPPGKATLAVEFSGELNDKMKGFYRSKYFSPTGE 296

  Fly   181 TRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESN-YLGDYTEAI-F 243
            .|....|:||.|.||:.|||:||||:||||.|:::.|: :..|:|||...|.. ...|.|... |
Mosquito   297 ERYAGVTQFEATDARRCFPCWDEPAIKATFDISLIVPT-NLVALSNMPVVEERPEPSDNTVHFKF 360

  Fly   244 ETSVSMSTYLVCIIVS--DFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYI 306
            :.:..||||||.::|.  |:....:   |:|:    .::.|....:..:..|||:....|..||.
Mosquito   361 DRTPVMSTYLVAVVVGEYDYVEDRS---ADGV----LVRVYTPVGKREQGRFALDVATKVLPYYK 418

  Fly   307 QYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQW 371
            .|:.:.|||.|:|:.||.||::||||:|||:|||||.:|.||..:|...|||||.|:.|||||||
Mosquito   419 DYFNIAYPLPKMDLIAISDFSAGAMENWGLITYRETFVLVDPENTSLIRKQSIALTVGHEIAHQW 483

  Fly   372 FGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKV 436
            |||||||:||..||||||:|.::::..|:.:.||:.:..||........|..|...:||||...|
Mosquito   484 FGNLVTMEWWTHLWLNEGYASFVEFLCVDHLFPDYDIWTQFVTDMYTRALELDCLRNSHPIEVPV 548

  Fly   437 ESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVVTD 501
            ..|.||..|||.|||.||.||||||...:|.|.|:..:..||.:||:|||.|:|....::. .:.
Mosquito   549 GHPSEIDEIFDEISYNKGASVIRMLHHYIGDEDFKRGMNLYLTRHQYNNTRTEDLWNALQE-ASS 612

  Fly   502 LDIKKLMLTWTEQMGYPVLNV--SKVADGS---FKVTQQRFLSNPASYEEAPSDSAYGYKWSVPI 561
            ..:..:|.||.::||:||:.|  ||..:|:   ..:.|.:|.::..   |||..|.    |.:||
Mosquito   613 KPVGAVMSTWIQRMGFPVVQVRSSKQLEGNRRVLSIAQSKFCADGC---EAPEQSL----WMIPI 670

  Fly   562 TWFADDGSENSF-------IYDYDVDSVGIAVPSEVQWIKLNVNQTGYYRVNY-EESLWALL--I 616
            . .:...|.|:.       ..|..|:.||     |..|:|:|....||||..| .|.|...|  |
Mosquito   671 N-VSTPSSGNAVSTVLETATADITVEGVG-----EQDWVKINPGTIGYYRTQYPAEMLEQFLPAI 729

  Fly   617 QQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRS 681
            :.:|..|     .||..|::|.|||..|.:.|....|.:......|.::..|...||.|..|...
Mosquito   730 KNMTLPP-----LDRLGLIDDLFALVQAGKSSTVDALKVIDAYRNENNYTVWSSISNCLAKLQLL 789

  Fly   682 LMFSEGYVSYLTYARSLIAGVYEEVGWTV-DADNHLKNRLRVSILTAACALGVPDCLQQASERFS 745
            |..:.....:..|...|...|.|::||.| ..::||...||..:|....:.|.|..:.:|..||.
Mosquito   790 LAHTPAEKQFSEYGVRLYQPVAEKLGWDVKPGESHLDTLLRSLVLGRLVSFGCPKTVAEAKRRFE 854

  Fly   746 TFLENPTTRPSPDLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLF 810
            ...:|.:..|: |||...|...:|.. ..:::|::.:|:.|.....||.::...|..:.|...|.
Mosquito   855 EHAQNKSVLPA-DLRSTCYRAVLQHG-DLATYDEMLRLYRATDLHEEKDRISRALGSIGNVDILR 917

  Fly   811 DFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFG----RLI 871
            ..:..|.|:|  ||:||....:..:|.||.|..:.|:::.|.|..|     ||....|    |||
Mosquito   918 KVIDFAMSEE--VRAQDSVFVIVSVAINPKGRDMAWDYFCEHWQVL-----LNQYEGGFLLARLI 975

  Fly   872 AQITANFASSVKLEEVQHFFSKYPESGAGANSRLEAVETIKYNIEWLSRNEADITDWL 929
            ..:|.||::..:.:||:.||.::...|. ..:..:::|||:.|.:|:.|:...|:.:|
Mosquito   976 KYLTENFSTEERAKEVEQFFREHDFPGT-ERTVSQSIETIRLNADWMRRDLDAISAYL 1032

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	178/452 (39%)
		ERAP1_C	592..912	CDD:463368	94/327 (29%)
Psa	XP_556379.4	None