Protein Alignment CG8774 and LOC1274368

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_061505691.1
• Gene: LOC1274368 / 1274368
• VectorBaseID: AGAMI1_004163
• Length: 818
• Species: Anopheles gambiae
• Alignment Length: 797
• Identity: 228/797 - (28%)
• Similarity: 370/797 - (46%)
• Gaps: 93/797 - (11%)

  Fly   182 RTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYH-AVSNMQQTESNYLGDYTEAIFET 245
            |.::||.|..||||..|||:|||..||.|.:.:.|  .|:| |:|||....|..:..|:|..|:|
Mosquito    26 RYLATTFFAATYARTVFPCYDEPGHKARFNVKIRH--RSHHTALSNMPVIRSTMIDGYSETTFDT 88

  Fly   246 SVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYK 310
            :..||||||..:||:..:.|:      |||.|  :.||..:::|...:|.:|..........::.
Mosquito    89 TPLMSTYLVAFVVSEMKTLSS------IGELF--RVYAPENKVNYTVYAHDFAVRAVRALENHFG 145

  Fly   311 VPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTA-NKQSIAGTLAHEIAHQWFGN 374
            ....:.|:|:..|||||.||||:||::|:||..|:|.....:|| .||.||..:.||:.|.||||
Mosquito   146 RQNQMRKIDLVGIPDFAMGAMENWGMITFREDYLIYQDEEKTTALAKQKIASVITHELVHMWFGN 210

  Fly   375 LVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESP 439
            .||.:||..:|||||||.:.:|...:.:.|.|.:.:||.:..:...|..|:..|..|:......|
Mosquito   211 EVTPEWWTYVWLNEGFANFFEYYITSQLEPAWRLWDQFILDNVHWALSKDSHSSVRPMNYYATDP 275

  Fly   440 DEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVVT-DL- 502
            ..:..::|.:.|||..|||||::.::|.:.|::|:.:||....:..|......|.:|...| ||
Mosquito   276 AVLNGLYDYVVYEKSASVIRMIQNVIGFDTFQQAINDYLRSRSYLTTRPQYLYTSIEKFRTVDLP 340

  Fly   503 -DIKKLMLTWTEQMGYPVLNVS-KVADGSFKVTQQRFLSNPASYEEAPSDSAY----GYKWSVPI 561
             .::.:..:|....||||:.|| .....:...:|:||.. |...:..|.:..:    .|..:||.
Mosquito   341 ASVEVIFESWANTPGYPVVTVSIDRTKRTLTASQKRFWM-PNELDTPPQNMLFYIPVNYGSNVPT 404

  Fly   562 TWFADDGSENSFIYDYDVDSVGIAVPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARF 626
            :...:|.:...::...| .:..:::.:.|:|:.:|..|||||||||::..|..||:.|.:.  :|
Mosquito   405 STDFEDTTPTFWLTPQD-PTATVSLEAGVEWVVVNKQQTGYYRVNYDDESWHKLIEVLNSD--QF 466

  Fly   627 E----IADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSLMFSEG 687
            |    :.:|..|::|...||.|.::.|.:.|.:..||.:|.:::||..|.|.|:.|.|.....:.
Mosquito   467 EDQLPVINRAQLVDDVANLARAGEVGYDVALSLMQYLERETEYIPWATAYNALQHLDRMFSSHKE 531

  Fly   688 YVSYLTYARSLIAGVYEEVGWTVDADNHLKNRLRVSILTAACALGVPDCLQQASERFSTFLENPT 752
            |..:..|...|.:.|:.|:. ..|.::||....|...:..||..||..||..|::.....|...|
Mosquito   532 YNRFENYVGILTSHVFNEMN-LFDTESHLNRLHRDKSVYLACYFGVEACLDAATKIIEEALAEET 595

  Fly   753 TRPSPDLREIVYY------------YGMQQSTSQSSWDQLFQLFVAETDASEKL--KLMYGLSGV 803
            .....:|:..|:.            ||:          ::||.:...||..:.|  |.:..|...
Mosquito   596 LNIPKELQNAVFCALHKYDLLVEGDYGL----------EIFQKYWLATDQYQPLMDKFINALGCS 650

  Fly   804 RNSQYLFDFLAQ------------ASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQL 856
            ||.. :.:|..|            .|...:|:.|.        |...|......:.:       :
Mosquito   651 RNLA-MNEFYLQMIEINETALPITVSMKNNILNSM--------IKGGPATRSAAFRY-------V 699

  Fly   857 TTRFGLNNRNFGRLIAQITANFASSVK-------LEEV--QHFFSKYPESGAGANSRLEAVETIK 912
            :.||...:......::.:......||.       |:|:  .|..|..|.|...|...|...|.
Mosquito   700 SARFDTVSNMLNHELSAMFNALGDSVNSPREYDMLKELIHTHQTSLNPSSMQAATRALAQAEE-- 762

  Fly   913 YNIEWLSRNEADITDWL 929
             |:.|::::...|..||
Mosquito   763 -NLHWIAKHSGVIAKWL 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	120/335 (36%)
		ERAP1_C	592..912	CDD:463368	86/358 (24%)
LOC1274368	XP_061505691.1	None