Protein Alignment CG8774 and LOC1273751

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_003436384.2
• Gene: LOC1273751 / 1273751
• VectorBaseID: AGAMI1_009321
• Length: 1054
• Species: Anopheles gambiae
• Alignment Length: 902
• Identity: 409/902 - (45%)
• Similarity: 558/902 - (61%)
• Gaps: 51/902 - (5%)

  Fly    66 YRLPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYVLN-----RE 125
            :|||.::.|.||||:..|||:...|:|:..|.:.|.|:||.|:|||..|.||...:..     .|
Mosquito   171 FRLPRHIRPVHYELWLQPDLQRETFSGRVGIELNVSESTNYIVLHSKKLSITETVLRTLGTGPEE 235

  Fly   126 V---EKFELEEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNE-AGATRTIST 186
            |   ..:||.|...::|.|..|..|  .:..|.:.|.|.:.|:::|.|||.||:: ...||||:|
Mosquito   236 VTIARAYELPEHEYWVIETQGEIGA--GAYRLSVQFNGSLADRIIGFYSSKYLDKTTNRTRTIAT 298

  Fly   187 TKFEPTYARQAFPCFDEPAMKATFAITVVHPSG-SYHAVSNMQQTESNYLGDYTEA-----IFET 245
            :|||||:|||||||||||.:||.:.|.:||||| .|.|:|||...|:  :.|...|     .||.
Mosquito   299 SKFEPTFARQAFPCFDEPHLKAEYTIHMVHPSGDGYAALSNMNVKET--VADKPSAGLSTTTFER 361

  Fly   246 SVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYK 310
            |||||||||..|||||..|...:.... |..|.::.|||..|.....:||...:.:.:||::|:.
Mosquito   362 SVSMSTYLVVFIVSDFLHQEVLIVPEH-GSSFPLRVYATPFQQENTAYALATARTIIQYYVKYFG 425

  Fly   311 VPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNL 375
            :.|||.||||||||||.|||||.|||||||||::||:...|||||||.:||.:|||:||.|||||
Mosquito   426 IAYPLPKLDMAAIPDFVSGAMETWGLVTYRETSILYNSVTSSTANKQRVAGVIAHELAHMWFGNL 490

  Fly   376 VTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPD 440
            |||||||:||||||||.|::|||::|.|||||:.|||.|..|..||..||.|.|||||..||:|:
Mosquito   491 VTMKWWNELWLNEGFASYIEYKGMDAAHPDWGIEEQFIIDDLHGVLNLDATLGSHPIVMSVENPN 555

  Fly   441 EITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVVTDLDIK 505
            :||.|||||:|.||.|||||||..|....|::.|..||.|..:.|:|::|.:.|::.:|.|:.:.
Mosquito   556 QITEIFDTITYSKGASVIRMLEDFVTPPVFQQGVKRYLEKLAYANSVSEDLMRELDELVPDVSVT 620

  Fly   506 KLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPIT-------- 562
            .:|.|:|.|.|.||:.|::.| ..:.:.|||||::..:.|  ..:|.|||:|.:|||
Mosquito   621 GVMDTFTRQKGLPVVTVAENA-LQYVLRQQRFLADQDANE--TEESPYGYRWYIPITYLASTDDP 682

  Fly   563 --------WFADDGSENSFIYDYDVDSVGIAVPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQL 619
                    ||.:|.|....:.|         .|:...|||||..|.|||||||..::|....:.|
Mosquito   683 ATAAPRRIWFPNDASRPELVID---------KPAGSSWIKLNYRQIGYYRVNYPIAMWQQFGEAL 738

  Fly   620 TTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSLMF 684
            ......|.|.||..|||||||||||:.|:|...|::|.||:.|.::|||...::||:::...|..
Mosquito   739 RKEVNTFTIGDRTGLLNDAFALADASLLAYNHALELTRYLSGETEYVPWSAIASKLKNIRNLLYN 803

  Fly   685 SEGYVSYLTYARSLIAGVYEEVGWTVDAD-NHLKNRLRVSILTAACALGVPDCLQQASERFSTFL 748
            .:.|....||.::|:....:.|||.|.|: .|:.|.||.:||..||:.|.|.||::||::|..:|
Mosquito   804 YQSYDDITTYTQTLVDAAVKSVGWDVPAEGGHMTNLLRTTILDLACSFGHPACLEEASKQFRGWL 868

  Fly   749 ENPTTRPSPDLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFDFL 813
             |......||||.:||.||:|...:.:.||::.:.|..|.||:||.|||..|:...:.:.:..||
Mosquito   869 -NDGAVIHPDLRSVVYTYGIQSGVTVADWDKVLERFRQENDANEKTKLMVALASYPDQRTMRRFL 932

  Fly   814 AQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQITANF 878
             ..|.|.::||:||..:|:||||||..||...||..||.||:|..|||:..||.||:|..:|..|
Mosquito   933 -DLSWDTALVRTQDQLSCIQYIAANRAGEQAAWEHVRENWPRLVARFGIGERNLGRMIPSVTGRF 996

  Fly   879 ASSVKLEEVQHFFSKYPESGAGANSRLEAVETIKYNIEWLSRNEADITDWLSGTASP 935
            .:..:|.|::.||::||||||||.:|.:|:|.|:.||.||.||||::..||....:|
Mosquito   997 TTQARLTELEDFFARYPESGAGATARRQALENIQNNISWLERNEANVAAWLKEATAP 1053

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	227/452 (50%)
		ERAP1_C	592..912	CDD:463368	139/320 (43%)
LOC1273751	XP_003436384.2	None