Protein Alignment CG8774 and LOC1273453

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_312430.6
• Gene: LOC1273453 / 1273453
• VectorBaseID: AGAMI1_008821
• Length: 1057
• Species: Anopheles gambiae
• Alignment Length: 955
• Identity: 276/955 - (28%)
• Similarity: 444/955 - (46%)
• Gaps: 123/955 - (12%)

  Fly    60 REDTTDYRLPTNLVPTHYELYWHPDLETG-----------NFTGQQRISIKVV--EATNQIILHS 111
            :::..:||||.|..|..|.:    :|.|.           .|.|:..|.:|..  ..|:.:.|:.
Mosquito    34 QDEQLNYRLPNNTYPLRYNI----ELTTRIHDSTIGDDRFRFEGKVTIQLKTAGDADTDNVTLNY 94

  Fly   112 YLLDITSVYVLNREVEKFE---LEEERQFLIITLTEELAV------DASITLGIIFGGQMKDKLV 167
            ..::||.|.:...:.:.:|   |::|..|.:.:..|.|.|      :.:..|.|.:.|.:::...
Mosquito    95 RRINITRVKLWYNDQDGWENILLDDELSFTLDSTREFLTVHSPKPLNGTYFLEIKYNGTLREDNG 159

  Fly   168 GLYSSTYLNEAGATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNM--QQT 230
            |.|.|:|.:..|..:.::||:|.||.||..|||:|||.::|..|:.|:| ..||..:||.  ...
Mosquito   160 GFYRSSYSDSDGNVQWLATTQFSPTDARHVFPCYDEPGIRAPIALRVIH-GKSYSVLSNTIPIDV 223

  Fly   231 ESNYLGDYTEAIFETSVSMSTYLVCIIVSD--------FASQSTTVKANGIGEDFSMQAYATSHQ 287
            ..:.|...:...|..:..|.:||:.|||||        |.:||..::|..:          |:..
Mosquito   224 RESILAGMSITTFPDTPKMPSYLLGIIVSDFKEVSLPNFTAQSAFIRATAL----------TTPV 278

  Fly   288 INKVEFALEFGQAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSS 352
            .|   |.||.|..:.:|..::.:.||.|.||...|||||:.||||::||:||:|...::||:.|.
Mosquito   279 AN---FILEAGFKILQYLEEFLETPYILPKLYHVAIPDFSPGAMENYGLITYKEENFMFDPNTSP 340

  Fly   353 TANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVAL 417
            ...|:.||..:.|||.|.:|||.|:..||:.||:.|||||:.:|.......|:..:.:.:.:...
Mosquito   341 MKQKKKIASIVGHEIGHHYFGNYVSPAWWSYLWMKEGFARFFEYTAAQIAFPELTIGKMYTVDKT 405

  Fly   418 QPVLLYDAKLSSHPIVQKVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYL---- 478
            ..|...||..|:.|:...|.|..||:.|||.|:|:|||:|:.||....|.|.|.:|:.|:|
Mosquito   406 HNVFQLDALGSTRPMTFYVNSQVEISNIFDDIAYDKGGAVLLMLYHAFGKEPFRQAMVNFLHVNA 470

  Fly   479 ----VKHQFNNTVTDDFLTEVEAVVTDLDIKKLMLTWTEQMGYPVLNVSKVADG-SFKVTQQRFL 538
                ...:|..::.....:.:.......:...|:.:||||.|||:::||:..|. |.::.|:|||
Mosquito   471 LQAGTPEKFAQSMQQTMFSSIPPTDPPFNALSLLKSWTEQAGYPIVHVSRSDDNCSLRIEQERFL 535

  Fly   539 SNPASYEEAPSDSAYGYKWSVPITWFA-------DDGSENSFIYDYDVDSVGIAVPSE------V 590
            ........|.|      .|.:|.. ||       ||.:...:|    ||...:..|:.      .
Mosquito   536 LKSTDASNATS------TWIIPYN-FATETQPNFDDTTATGWI----VDKYHVINPTADHSWTCD 589

  Fly   591 QWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPLDM 655
            .||..|..|||||||||::.||.|:::.|..:......::|..|::||..:|.|.:|:|.|||.:
Mosquito   590 SWIVFNKQQTGYYRVNYDDQLWQLIVKALVQNGTIIHESNRAQLIDDALNIARAGKLAYAIPLQL 654

  Fly   656 TAYLAQERDFVPWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYEEVGWTVDADNHLKNRL 720
            ..||::|.|::||......|..|...:..::.|..:..|....|...|.|:|......:.|..|:
Mosquito   655 LRYLSKENDYLPWAALDRNLVVLDNLMRGTDSYDDWHKYCSEFIEPSYVEMGMVTQPQDTLTQRM 719

  Fly   721 -RVSILTAACALGVPDCLQQASERFSTFLENPTTRPSPDLREIVYYYGMQQSTS----------Q 774
             |..::..||.:|...|:.......:....|||....|||||.:|..|::.|.:          |
Mosquito   720 TREIVINWACKVGSEACINSTRLMVAEIAGNPTKDAEPDLREAIYCNGLRYSAATVFDSIWRKMQ 784

  Fly   775 SSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQ---YIA 836
            .|.|||:           :.:|:..|....|::.:..:| |::.|..   :..||...:   :||
Mosquito   785 QSQDQLY-----------RSELIRSLGCAENAELIAKYL-QSTIDTD---NSTYFNQERERVFIA 834

  Fly   837 A---NPVGEPVVWEFYREQWPQLTTRFGLNNRNF-GRLIAQITANFASSVKLEEVQHFF----SK 893
            .   :.:|..:...|.||...::...:  |..|| ||.|..|....|..:..|.:|..|    ::
Mosquito   835 VFKNSLLGLEMAMNFLRENSERVNELY--NKGNFGGRAINSIIRTMAQQITSEAMQTKFQTLTAE 897

  Fly   894 YPESG-AGANSRLEAVETIKYNIEWLSRNEADITDWLSGTASPLT 937
            ..|.| ...:..|:|:|....|::|:......||.||.....|.|
Mosquito   898 LHEKGFLRESDMLQALEYSSENLKWIEEKSVQITAWLDEQYRPTT 942

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	142/477 (30%)
		ERAP1_C	592..912	CDD:463368	94/342 (27%)
LOC1273453	XP_312430.6	None