Protein Alignment CG8774 and LOC1272139

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_311017.5
• Gene: LOC1272139 / 1272139
• VectorBaseID: AGAMI1_006784
• Length: 953
• Species: Anopheles gambiae
• Alignment Length: 957
• Identity: 224/957 - (23%)
• Similarity: 409/957 - (42%)
• Gaps: 153/957 - (15%)

  Fly    64 TDYRLPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYVLNREVEK 128
            :|.:|||:|||:.|.|:.||.|:...|:|:..|::...:|||||.||:: .|:|        |::
Mosquito    43 SDTKLPTDLVPSGYSLHLHPVLDRSIFSGRVNITLLCAKATNQINLHAH-HDLT--------VDE 98

  Fly   129 FELE---------------------EERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSS 172
            .|||                     .::..|:|...:.|...|:..:.:.|.|.:.:.:.|::..
Mosquito    99 LELEVVRIGGAEGGTKVPIRRVDRVPKKPLLVIYFHDALTAGAAYEVRLRFVGNIWENVEGIFEG 163

  Fly   173 TYLNE--AGATRTIST---------------TKFEPTYARQAFPCFDEPAMKATFAITVVHPSGS 220
            .|..:  .|.:....|               |.|.|.:||:.|||||||:.|..|.:::|.|. :
Mosquito   164 KYKQQQSTGPSEPAGTESEGVTEPEEHSFIGTYFRPHHARRVFPCFDEPSYKVPFNVSIVRPR-T 227

  Fly   221 YHAVSN--MQQTESNYLGDYTEAIFETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDF----SM 279
            :|.:.|  :::|.....|.:...:|:.:..|||:....:|||.  |..|...:...||.    ::
Mosquito   228 HHVLFNTALERTVETGDGKHVIDVFKQTAPMSTFTFGFLVSDL--QQVTPSLSDEKEDERLKPTI 290

  Fly   280 QAYA-TSHQIN------KVEFALEFGQAVTEYYIQYYKVPYPLTKLDMAAIPDFA-SGAMEHWGL 336
            :.:| ...|.|      :|:.||...|       :|:.||.||.|||:.|:|.|: ....::|||
Mosquito   291 RVWARRDFQKNVADVQQRVKLALRKLQ-------EYWGVPLPLEKLDVVALPGFSYVKPADNWGL 348

  Fly   337 VTYRETALL---YDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKG 398
            :.::|:.|:   |:               ||.|:.:||.|:.:|..||:|..:|:..|.::  ..
Mosquito   349 IVFKESELMRGYYN---------------LAQELVYQWLGSWITPHWWSDAHVNKAIAGFL--SA 396

  Fly   399 VNAVHPDWGMLEQFQ----IVALQPVLLYDAKLSSHPIVQKVESPDEITAIFDTISYEKGGSVIR 459
            ..|:..|.|  ::|:    :..|..:....:|...|         ..|||:....:..|...|:|
Mosquito   397 DTAIKIDGG--DEFEGKYPMTILYSIYYEFSKRYPH---------SRITAMKQETTCSKTELVLR 450

  Fly   460 MLETLVGAEKFEEAVTNYLVKHQFNNTVTDDF---LTEV----EAVVTDLDIKKLMLTWTEQMGY 517
            ||...:|.|.|...:..::...::.....:|.   ||:.    :.:...:.:..::.:|..:...
Mosquito   451 MLNYTLGEETFRRGLQRFIQHREYKTFYGEDVWEALTKQAHLDQRLCESVTVNDVVNSWITKDRI 515

  Fly   518 PVLNVSK-VADGSFKVTQQRFLSNPASYEEAPSDSAYGYK--WSVPITWFADD----GSENSFIY 575
            |::.|.: .|:.:..|||:.:|      .|.|.|.....|  |.:|:.....|    |:.::..:
Mosquito   516 PMVRVVRSYANRTATVTQRLYL------RERPHDVPEQDKMLWWIPLVVVRQDRLNFGNVSTIRW 574

  Fly   576 DYDVDSVGI-AVPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPAR--FEIADRGHLLND 637
            ...|..|.: .:|...::|.:|..:.|.:.|||:|..|.||...|....:|  ..:..|..||:|
Mosquito   575 MKQVREVTLDELPGPDEFIIVNPEEIGPFPVNYDERNWNLLATFLQKEESRTMIPVYTRAKLLHD 639

  Fly   638 AFALADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGV 702
            |:.||.|..||:....:||.::..||:.:.|......:..:.|.:..|..:..:..|.|:|:..:
Mosquito   640 AWNLAYAGDLSFGTAFNMTLFMKYERNHLVWNPVFTLIDHIGRHIDMSAVHKKFEMYVRTLLTPL 704

  Fly   703 YEE-VGWTVDADNHLKNRLRVSILTAACALGVPDCLQQASERFSTFLENPTTRPSPDLRE----- 761
            ||| ||...:::...|..||.......|..|...|:::|...|..::::    |.||...
Mosquito   705 YEELVGNQQESEEMWKANLRSLAKNFLCRAGYKPCIEEAQRAFKKWMDS----PDPDAGNPVANQ 765

  Fly   762 ---IVYYYGMQQSTSQSSWDQLFQLFVAETDA---SEKLKLMYGLSGVRNSQYLFDFL--AQASS 818
               .|:.:|     ::..|:...|..:...::   ||:..|:..|:|..:..:..|.|  .....
Mosquito   766 FICPVFKWG-----TREEWEFGLQRVINFPESRVKSERTYLLKTLAGCPSQPFKIDRLLNIMVLE 825

  Fly   819 DESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQITANFASSVK 883
            |.......|.....:.::....|...::.|.:..|..:..||......:..:|...|..|.:...
Mosquito   826 DNGNFTDNDISLIFKMLSGGSSGYSTLFNFLKNNWDAIKLRFKDRESLWDNMINSATGLFTTQEG 890

  Fly   884 LEEVQHFFSKYP-ESGAGANSRLEAVETIKYNIEWLSRNEADITDWL 929
            .:.|...:.::. |.|...:...::::.||...:|...|...|..||
Mosquito   891 YDMVSQLYVQHQGEFGTAEHIIEKSLKNIKEETKWSDENLPVIEQWL 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	120/503 (24%)
		ERAP1_C	592..912	CDD:463368	72/336 (21%)
LOC1272139	XP_311017.5	None