Protein Alignment CG8774 and LOC1272138

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_061498983.1
• Gene: LOC1272138 / 1272138
• VectorBaseID: AGAMI1_007516
• Length: 1141
• Species: Anopheles gambiae
• Alignment Length: 923
• Identity: 211/923 - (22%)
• Similarity: 367/923 - (39%)
• Gaps: 152/923 - (16%)

  Fly    32 QLERDL-------RDVQDKIDVFEEWSGESRTRMKREDTTD------YRLPTNLVPTHYELYWHP 83
            ||.:|.       |:.::|.||.||.:| |.|.:....|.|      ..:....:....:.|.||
Mosquito   253 QLPQDAAGADETEREGEEKEDVSEEVAG-SETEVAEPGTVDPGPNSSGSVENATIIDKSKFYHHP 316

  Fly    84 DLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYVLNREVEKFELEEERQFLIITLTEELAV 148
            .....:|     ::||:             |||             |.:|..:.:||.|..|:..
Mosquito   317 VFPADDF-----VTIKI-------------LDI-------------EFDESNEKMIIFLGTEMKK 350

  Fly   149 DASITLGI-IFGGQMKDKLVGLYSSTYLNEAGATRTISTTKFEPTYARQAFPCFDEPAMKATFAI 212
            |....:.: .||....||  |||.:.|.::....|..:.|..||..||:.:||.|:...::.|.:
Mosquito   351 DIYYIVKVNFFGNMTNDK--GLYYTHYEDDGPDHRHFAATVLEPNNARRLYPCMDDHNFRSPFEL 413

  Fly   213 TVVHPSGSYHAVS-NMQQTESNYLGDYTEAIFETSVSMSTYLVCIIVSDFASQSTTVKANGIGED 276
            .:...|....|.| |::.:|....||.....:.|:..:....:..:|:|...:...:.|.
Mosquito   414 NIARKSDMNTASSMNLEMSEPMETGDIVVDTYNTTDMVRASEIGFVVTDMVPERYRITAR----- 473

  Fly   277 FSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAME-HWGLVTYR 340
            .|:.|:..:.....::.|........:.|.||..||:|...:....||:......| ..|:|...
Mosquito   474 VSLLAFTRTRYDENIKNATSVFSRALQIYEQYLGVPFPYEVIRYVTIPNIDHQTYEIKEGMVLSS 538

  Fly   341 ETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGV-NAVHP 404
            |..|:....|....:| ||...:|:|:|..:...|...|.....||:|....|::...: |....
Mosquito   539 EKRLIKTADYFPPLDK-SINREVANELAKLFIHKLADYKNKETYWLHESLPLYLEALALRNMTTA 602

  Fly   405 DWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPDEITAI------------FDTISYEKGGSV 457
            :...|:.|         |.:.:|.|    .:.|...:.:|:            |:.:.| ||.||
Mosquito   603 NSTTLDDF---------LLEGRLRS----MREEMNTKTSALNIFTNHWEEDTHFELVKY-KGLSV 653

  Fly   458 IRMLETLVGAEKFEEAVTNYLVKHQFNNTVTD--DFL---TEVEAVVTDLDIKKLMLTWTEQMGY 517
            :||:...:|...|:..|..|. :::..:...|  |.|   :...|..||......:.:|:....|
Mosquito   654 LRMMNYTLGQRTFDRFVREYF-RYRMESESIDVIDILNGGSGEGASRTDGVFHSFLYSWSSLEKY 717

  Fly   518 PVLNVSK-VADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFADDGSENSFI----YDY 577
            |::|:.: .|.|.:::.|     .|..:||.|::..    |:||:| |.:|.::..|:    :..
Mosquito   718 PIINIRRNNATGYYELRQ-----IPLPFEEEPAEQL----WTVPVT-FINDTNQRLFVEKVRWLT 772

  Fly   578 DVDSVGIAVPSE-------VQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLL 635
            |.::: :.|.|:       ..||.:|.:..||||||||.:.|..|...|..:...........::
Mosquito   773 DEENL-LTVQSDCSTSNGSASWIIVNPSGIGYYRVNYEPAHWIKLAHVLYGNFHYLPYTTLAIIV 836

  Fly   636 NDAFALADANQLSYKIPLDMTAYLAQERD-FVPWYVASNKLRSLHR------SLMFSEGYVSYLT 693
            :||..||....|:|.:..::.::|....: :.||.:|.:.|..::.      |....|.::.|
Mosquito   837 DDALNLARLGLLNYSVAFNVVSFLKHNNEHYQPWKLALSNLEFVYHATEDLPSFRHVERFLEY-- 899

  Fly   694 YARSLIAGVYEEV--GWTVDADNHLKNRLRVSILTAACALGVPDCLQQASERFSTFLENPTTRPS 756
                ||...|||:  |   :...|....::..|:..||.|||..|::|....|...|.|.|..|.
Mosquito   900 ----LILSKYEEIQRG---NETAHYNPLIKELIVQWACKLGVTSCIEQHKALFQAILRNQTVSPF 957

  Fly   757 PDLRE--------IVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFDFL 813
            ....|        .:.|.|:      :.|.::.|.:...||.:.:..|:..|...|....:..:|
Mosquito   958 EQREERLHRILCTTIKYSGL------AEWKRVEQQYRETTDINYQRILIKSLGCTREISMIKRYL 1016

  Fly   814 AQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQITANF 878
            .........:.|::..|.   |:.|.|......:|...:|  |..|..|..::...|:..|:.
Mosquito  1017 GLLKHPHFRMYSKEILTA---ISENKVALKYTLDFLFNEW--LDVRLYLTLQDISILLRSISN-- 1074

  Fly   879 ASSVKLEEVQHFF 891
            .:..|:.| |.||
Mosquito  1075 MNEFKMYE-QIFF 1086

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	101/458 (22%)
		ERAP1_C	592..912	CDD:463368	76/317 (24%)
LOC1272138	XP_061498983.1	None