Protein Alignment CG8774 and LOC11176075

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_061503385.1
• Gene: LOC11176075 / 11176075
• VectorBaseID: AGAMI1_012706
• Length: 1065
• Species: Anopheles gambiae
• Alignment Length: 966
• Identity: 322/966 - (33%)
• Similarity: 494/966 - (51%)
• Gaps: 125/966 - (12%)

  Fly    52 GESRTRMKREDTT-------DYRLPTNLVPTHYELYWHPDLETGNFT--GQQRISIKVVEATNQI 107
            |:.:...:.||.|       |.|||.::.|..|::...|.|...|||  |...:.:.|:|..:.:
Mosquito   136 GKDQGGQRAEDGTVASSVREDLRLPRSIEPVAYDIRLIPWLVEDNFTFLGTVEVLVNVLEDCSNV 200

  Fly   108 ILHSYLLDITSVYV-------------------------LNREVEKFE---LEEERQFLIITLTE 144
            .||...|:|.|..|                         |.||:.:.:   ....:||.::.|..
Mosquito   201 TLHVAALNIHSASVERSTGRGEEQHSEAATADESSEGAPLVREMVEIDHNLTVASKQFYVLMLKT 265

  Fly   145 ELAVDASITLGIIFGGQMKDKLVGLYSSTYL--NEAGATRTISTTKFEPTYARQAFPCFDEPAMK 207
            .|.......:.:.:.|.:.|.|.|.|.|:|.  ||   ||.|:||:|:||.||:|||||||||:|
Mosquito   266 PLRRGEQYVVRLRYDGVLNDYLQGFYRSSYTANNE---TRWIATTQFQPTDARRAFPCFDEPALK 327

  Fly   208 ATFAITVVHPSGSYHAVSNMQQTESNY------LGDYTEAIFETSVSMSTYLVCIIVSDFASQST 266
            |.|.|::.. :....::|||.:..| |      |..|...:::.||.||||||..:|.|:.:.::
Mosquito   328 ARFNISIAR-TRDMISLSNMPRLRS-YEASEPELQGYVWDVYQQSVPMSTYLVAFVVCDYLNLTS 390

  Fly   267 TVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAM 331
            .          :...:|.:..|....:||..|..:.::...::.:.|||.|:||.|:|||::|||
Mosquito   391 G----------NFAVWARADAIGSARYALSVGPKLLKFLEDFFHIEYPLPKVDMIALPDFSAGAM 445

  Fly   332 EHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQY 396
            |:|||:||||||:||:.:.|:.:|||.:...:|||:||||||||||..||.|||||||||.||:|
Mosquito   446 ENWGLITYRETAMLYEENVSAISNKQHVITVVAHELAHQWFGNLVTPSWWTDLWLNEGFASYMEY 510

  Fly   397 KGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPDEITAIFDTISYEKGGSVIRML 461
            .||:||.|.|..:|||.:..|..|...||..|||.|..:|.:|:||..|||.|||.||.::|||:
Mosquito   511 LGVDAVEPAWKSMEQFVVNELHNVFSLDALSSSHQISVEVHNPEEIHEIFDKISYGKGATIIRMM 575

  Fly   462 ETLVGAEKFEEAVTNYLVKHQFNNTVTDD---FLTEVEA----VVTD-LDIKKLMLTWTEQMGYP 518
            :..:..|.|:..:||||...::.:...||   :||. ||    :..| ..:|::|.|||.|.|:|
Mosquito   576 DHFLTTEVFKRGLTNYLNDKKYQSASQDDLWEYLTN-EARRGGIFDDHTSVKEIMDTWTLQTGFP 639

  Fly   519 VLNVSK-VADGSFKVTQQRF-LSNPASYEEAPSDSAYGYKWSVPIT----------------WFA 565
            |:.|.: ....|.:..|:|| .:|..:..:..:..:..:.|.:|||                |.
Mosquito   640 VVFVQRDYESDSIEFRQERFSFANALNGTDGVARHSERFLWWIPITYTTLGDSNFQQTKPSIWM- 703

  Fly   566 DDGSENSFIYDYDVDSVGIAVPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIA- 629
             ...|...|.::|       :||. .|:.:||.|||||||||:|..|.::::.|........||
Mosquito   704 -KAEEALVINNHD-------IPSH-DWMIVNVQQTGYYRVNYDERNWQMIVRHLQDRNKYKTIAA 759

  Fly   630 -DRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSLMFSEGYVSYLT 693
             :|..|::||..||.|..|.|.:.|::|.||..|.|:|||..|...|..:....:.:..|..:..
Mosquito   760 SNRAQLIDDALNLARAGYLDYGVALNVTRYLVHETDYVPWKAAIAALNYIDSMFIRTRNYGLFKK 824

  Fly   694 YARSLIAGVYEEVGWTVDADNHLKNRL-----RVSILTAACALGVPDCLQQASERFSTFLENPT- 752
            |:..|:..:|.|||:    ::|..:.|     |:|:|.|.|.||..||:.....::..::..|.
Mosquito   825 YSMDLLENIYREVGF----EDHRDSPLLTVYKRISVLKAVCHLGNKDCVNHCLRKYYEWMHQPNP 885

  Fly   753 --TRP-SPDLREIVY----YYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLF 810
              ..| ||:|:..||    .||     .::.||..::.|...|.||||..|:..:...|....|.
Mosquito   886 DINNPISPNLKSTVYCTAIKYG-----DETEWDFAWERFQKATVASEKEILLSAMGCSRVPWILA 945

  Fly   811 DFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQIT 875
            .:|..|.|||..:|.||.|.....:|.|.:|:|:.:::.|..|.::.:.||.:..|...::...|
Mosquito   946 RYLENAMSDEYGIRKQDAFRVFISVADNVIGQPIAFDYMRNNWAKMKSYFGASMSNLNIILKYCT 1010

  Fly   876 ANFASSVKLEEVQHFFSKY-PESGAGANSRLEAVETIKYNIEWLSRNEADITDWLS 930
            ..|.:..:|.|::.|...: .:||   .:..:|:|..:.||.||:||...|.:||:
Mosquito  1011 KRFNTESELLELKEFAEIHLKDSG---RTIQQAIEWTESNIAWLNRNAQPIVNWLN 1063

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	181/483 (37%)
		ERAP1_C	592..912	CDD:463368	102/335 (30%)
LOC11176075	XP_061503385.1	None