Protein Alignment CG8774 and LOC11175890

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_003435967.2
• Gene: LOC11175890 / 11175890
• VectorBaseID: AGAMI1_011008
• Length: 939
• Species: Anopheles gambiae
• Alignment Length: 981
• Identity: 301/981 - (30%)
• Similarity: 477/981 - (48%)
• Gaps: 131/981 - (13%)

  Fly    10 VVLSWAVVAFATATVVVAVQKAQLERDLRDVQDKIDVFEEWSGESRTRMKREDTTD--YRLPTNL 72
            :||...||:.:|..|......|..|.:.|          |::....|...|:|:.|  |||||:.
Mosquito     9 IVLLLLVVSSSTLAVFGQRSAAHPEWNNR----------EFAPAPDTSSPRDDSIDQSYRLPTDT 63

  Fly    73 VPTHYELYWHPDLETGN--FTGQQRISIKVVEATNQIILHSYLLDITSVYVLNREVEKFELE--- 132
            |||||.:..|.||.||:  |:|...|...||..|:.|::|:..|.|.|..:..::.:...:|
Mosquito    64 VPTHYTIRLHTDLHTGSRAFSGIVDIEFDVVVPTDAIVVHNRDLLIASAALYAKDQDGLLVEFGF 128

  Fly   133 -----EERQFLIITLTEELAVD-------ASITLGIIFGGQMK-DKLVGLYSSTYLNEAGATRTI 184
                 ::|       ||:|...       .|..|.:.:.|.:: ....|.:..:|:|:.|..|.:
Mosquito   129 PHHEFDQR-------TEQLTFHPGQVLPIGSYVLTVEYSGLLQTSSNSGFFLKSYVNDDGERRYV 186

  Fly   185 STTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTE---SNYLGDYTEAIFETS 246
            .||:||.|.||.||||:|||.:||.|.:.:.| ...|:|||||...|   |.....|....|..:
Mosquito   187 GTTQFESTNARMAFPCYDEPLLKAGFTLWITH-IAEYNAVSNMPVEEVVPSEEHEGYVTTKFGPT 250

  Fly   247 VSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFG----QAVTEY-YI 306
            ..||:||:...||||.:.          ||.:.|.||..:.:::.||.||.|    .|::|| |:
Mosquito   251 PKMSSYLLAFGVSDFVAL----------EDGNQQLYARPNAMDEAEFGLEAGVKILDALSEYTYV 305

  Fly   307 QYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQW 371
            .||..   :.||...||||...||||:||||.|.||.||:||:.::...::.||..:|||:||||
Mosquito   306 NYYDY---MPKLSQMAIPDRGGGAMENWGLVKYAETGLLFDPARNTYRTRKGIAVVVAHELAHQW 367

  Fly   372 FGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKV 436
            ||:||..:||:.:|||||||....|.|.:..:|.....:.:.:..:|.....||..|:.|:.|..
Mosquito   368 FGDLVGPQWWSYIWLNEGFANLYGYIGADLAYPSERYWDLYAVENVQNAFGPDATDSTRPMTQDA 432

  Fly   437 ESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVVTD 501
            .:|..|:.:||:|:|:|.|||:.|...::|.:.|...:..||:..|.:..|.||....::|.:.|
Mosquito   433 TTPSAISGLFDSIAYDKSGSVLNMFRMVLGDDNFRAGLKVYLLNRQLDGAVADDLYAGLQAAIDD 497

  Fly   502 LD-------IKKLMLTWTEQMGYPVLNVSK-VADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWS 558
            .|       :|:||.:||.:.|||||.|.: ..|||..::|:||.::    :.:|:.:.    |.
Mosquito   498 KDVLPDGYTVKQLMDSWTTEPGYPVLTVRRNYNDGSAILSQERFYAD----KRSPNANV----WY 554

  Fly   559 VPITWFADDGSENSFIYDYD-----VDSVGIAVPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQ 618
            :|.::.:....:...:.|:.     .:.:.....:: :||..|..|||||||||:...|.::...
Mosquito   555 IPYSFASASSPDFEDLSDFQWLSTKAERIETGASAD-EWIIFNKQQTGYYRVNYDAHNWLMIANA 618

  Fly   619 LTTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSLM 683
            |...|:.....:|..|:||||.||.|.:....:.|||..||:.|.::.||..|:..|...:..|.
Mosquito   619 LREDPSAIHRFNRAQLINDAFNLARAGRHDLALTLDMLRYLSNEHEYTPWAAANGVLNYFYNKLR 683

  Fly   684 FSEGYVSYLTYARSLIAGVYEEVG--WTVDADNHLKNR-LRVSILTAACALGVPDCLQQASERFS 745
            .:..|..::.|..:||..|::..|  .||..|..|.:: |:..|.|.||.:|..:||:|.:|...
Mosquito   684 GTANYHDFIVYVDALIGPVFDSFGDIATVPEDETLLDKYLKQLISTWACRVGYTECLRQTAEALH 748

  Fly   746 TFLENPTTRPSPDLREIVYYYGMQQST-SQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYL 809
            |.:|. .|...||:..:||.||::.:| .:..|  ||...:...:.:|:..|:..|...::...|
Mosquito   749 TAVET-NTPVHPDVSYVVYCYGLKGATDDEYRW--LFDQMINSNNEAERQLLIDALGCAQDQSQL 810

  Fly   810 FDFLAQA--SSDE-------------SIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTR 859
            ...|..|  |:.|             |.:.|...|.....|.|  :.:|::.:       :...|
Mosquito   811 ISLLTVAIGSNSELNSLLNGERSRIVSSIYSAGRFGVEAMIEA--LSDPLLAQ-------EFVGR 866

  Fly   860 FG---LNNRNFGRLIAQITANFASSVKLEEVQHFFSKY-----PESGAGANSRLEAVETIKYNIE 916
            ||   |||     :::.:.:...:..:||:::.|.:..     ||:.|.      ||.|:|.|..
Mosquito   867 FGQGTLNN-----VVSNVASRTNNDGELEQLEQFLAALGDLISPETAAA------AVRTVKTNAA 920

  Fly   917 WLSRNE 922
            |....|
Mosquito   921 WFETYE 926

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	162/470 (34%)
		ERAP1_C	592..912	CDD:463368	97/346 (28%)
LOC11175890	XP_003435967.2	None