Protein Alignment CG8774 and LOC11175889

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_003436573.2
• Gene: LOC11175889 / 11175889
• VectorBaseID: AGAMI1_012506
• Length: 935
• Species: Anopheles gambiae
• Alignment Length: 920
• Identity: 277/920 - (30%)
• Similarity: 453/920 - (49%)
• Gaps: 70/920 - (7%)

  Fly    60 REDTTDYRLPTNLVPTHYELYWHPDLE-TGN-----FTGQQRISIKV-VEATNQIILHSYLLDIT 117
            |....||||..::.||||::...|.|| .||     |.|..:|::.. .:...||.||...:|||
Mosquito    39 RAQPEDYRLNDDVWPTHYDIEIKPYLEQEGNKAQFTFDGSAKITVSTQKQNVMQIKLHMARMDIT 103

  Fly   118 SVYVLNREVEKF------ELEEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLN 176
            :..|..:.....      ..::|.|.|.:.|:..|..:....|...:.|.|.|.:.|.|.|.|.
Mosquito   104 AWSVTRKSDNTIIPTLPQTYDQETQILTLPLSSALQANVEYVLSFTYVGNMDDDMHGFYRSYYW- 167

  Fly   177 EAGATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSN--MQQTESNYLGDYT 239
            |.|....:.:|:|:.|:||:||||||||..||||.:.:.|.: .|:..||  :..|....:| .|
Mosquito   168 EDGVKVWMGSTQFQQTHARRAFPCFDEPRFKATFQLKINHKT-QYNVYSNTAIVGTAVAEVG-RT 230

  Fly   240 EAIFETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEY 304
            ...|..:.|||:||:..||:.:.          |.:...|...|.....|:.:::|:.|..:.:.
Mosquito   231 LTTFGVTPSMSSYLIAFIVAPYQ----------INDRDGMGILARPQAQNQTQYSLDVGIKLLKA 285

  Fly   305 YIQYYKVPYP----LTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAH 365
            ..::...||.    :|::.|||:|||::||||:|||:|||||.:||....|::..:..||..::|
Mosquito   286 LEEWIDYPYASVAGMTRMYMAAVPDFSAGAMENWGLLTYRETNILYRSDDSTSMQQHRIAAVISH 350

  Fly   366 EIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSH 430
            ||||||||:|||.:||:..|||||||||.||.|...|..:|.:..||.:..||.|:..|:..|:|
Mosquito   351 EIAHQWFGDLVTCEWWDVTWLNEGFARYYQYYGTALVETEWNLDHQFVVEQLQGVMQMDSLRSTH 415

  Fly   431 PIVQKVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEV 495
            |:...|.:..:.:.|||.|||.||..::||:|..:..|.|:.|:..|:....|..|..:|..:.:
Mosquito   416 PMTHPVYTQAQASGIFDNISYNKGAVMLRMMEHYLTTETFKTALRAYIKDRAFKTTRPEDLFSAL 480

  Fly   496 EAVVTDLDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVP 560
            ...  |.:.:..|..||.|.|||::.|:. .|..|.:||:|||.|...:.|.       ..|.:|
Mosquito   481 NRY--DPNARSYMEPWTIQSGYPLVTVTS-HDTGFTITQKRFLVNEPDHNEQ-------IAWPLP 535

  Fly   561 ITWFADDGSENSFIYDYDVDSVGIAVP----SEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTT 621
            || ||...||.|.........:...:|    |:|::..||..|.|||||||:..||..:.:.|.:
Mosquito   536 IT-FATKASEFSITRPAFYTGMTFEIPMQGASDVEYFILNNQQVGYYRVNYDAILWGKISKALHS 599

  Fly   622 SP-ARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSLMFS 685
            .. ....:.:|..:::|.|.||..:.:.|...|::..||.:|.::.||..|.|.|.:|.|.: .:
Mosquito   600 EGFGGIHVLNRAQIVDDLFNLARGDVVPYGTALEILEYLKEETEYAPWLAAVNGLTTLSRRI-HA 663

  Fly   686 EGYVSYLTYARSLIAGVYEEVGWTVD--ADNHLKNRLRVSILTAACALGVPDCLQQASERFSTFL 748
            :....:..:...:.:..|:.|.:...  .:..:...:|.::|..||..|..:|.:.|...|..:.
Mosquito   664 DDEKLFAAHILDIFSKAYDIVKFQAPTATERRIFTYMRQNVLQWACNYGHEECSKAAVAEFHRYH 728

  Fly   749 ENPTTRPSPDLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFDFL 813
            :||:.:..||||::||..|:::.::: .::.|:..::....|:|::.::.||..|.:|:.:.|.|
Mosquito   729 QNPSVKVHPDLRQVVYCEGIRKGSTE-EFEFLWNQYLTTNVATEQILILQGLGCVSSSELITDML 792

  Fly   814 AQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQITANF 878
            ...:|..  |||||......|:..||...|.|..:.::.........|....     :|....|.
Mosquito   793 NGIASPH--VRSQDKNNAFTYVINNPYTLPHVSRYLQQNHANWAASHGSYTN-----VASAFNNV 850

  Fly   879 ASSVKLEEVQHFFSKYPESG------AGANSRLEAVETIKYNIEWLSRNEADITDWL-----SGT 932
            .:.:|.:..:...|.:.||.      |..:|....:|..:.|.::..||..:|.::|     .|.
Mosquito   851 LARLKSDSERDAISAFIESNKNILGQAAYDSIKSGLEDYETNKQFTLRNRDEIHEFLDNKINGGA 915

  Fly   933 ASPLTKKNQL 942
            |:.|...:.:
Mosquito   916 ATILANVSMI 925

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	157/456 (34%)
		ERAP1_C	592..912	CDD:463368	79/328 (24%)
LOC11175889	XP_003436573.2	None