Protein Alignment CG8774 and LOC11175863

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_003436569.2
• Gene: LOC11175863 / 11175863
• VectorBaseID: AGAMI1_006225
• Length: 996
• Species: Anopheles gambiae
• Alignment Length: 993
• Identity: 291/993 - (29%)
• Similarity: 478/993 - (48%)
• Gaps: 142/993 - (14%)

  Fly     9 QVVLSWAVVAFAT---ATVVVAVQKAQLERDL-------RDVQDKIDVFEEWSGESRTRMKREDT 63
            |.||:...:|..|   ..::|::..|.|:|..       ..:.|::|:      :||.:::
Mosquito    46 QKVLTICHLAMGTIVQIVILVSLGLANLQRSTVSCTPLHSQLFDEVDL------QSRAQLE---- 100

  Fly    64 TDYRLPTNLVPTHYEL----YWHPDLETGNFTGQQRISIKVV---EATNQIILHSYLLDITSVYV 121
             :|||..::.||||::    |:.|:.|...||.....:|.|.   :...||.||...:::|...|
Mosquito   101 -EYRLNDDVWPTHYDIEIKPYFEPEPEKEAFTFDATTTIAVTVLKDNVTQIKLHKAHMNVTDWRV 164

  Fly   122 LNRE----VEKFE--LEEERQFLIITL-TEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNEAG 179
            :.:.    |.|..  ..||.|...:.| ..||..:....:.:.:.|:|::.:.|.|.| |....|
Mosquito   165 MRKSNSMPVGKVNETYNEETQIWTLNLKPSELVKNVEYNIVVNYVGRMEEDMGGFYRS-YFKVNG 228

  Fly   180 ATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSN---MQQTESNYLGDYTEA 241
            ....:.:|:||.|.||:||||||||..|.||.:.:.:....|:..:|   :....:.|  :.|.|
Mosquito   229 KQVWLGSTQFEQTEARRAFPCFDEPRYKTTFTLKLDYKPDEYNVYANTPIVNSVPTRY--NRTLA 291

  Fly   242 IFETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYI 306
            .|..:..|||||:..||:.:..:|:.|          |...|....:|:.:::::.|..:.:...
Mosquito   292 SFGITPKMSTYLLAFIVAPYELKSSDV----------MGVLARPEALNQTDYSVQEGLKLLKALG 346

  Fly   307 QYYKVPY----PLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEI 367
            .:...|:    .:|::.||||||||:||||:|||:||||::|||....:::..:|.||..::||:
Mosquito   347 NWVDYPFNSVPEITRMYMAAIPDFAAGAMENWGLITYRESSLLYVEEDATSMQQQRIASIISHEL 411

  Fly   368 AHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPI 432
            ||||||||||.:||:..|||||||.|.:|.|...|.|.|.:..||.:..||..:..|..|::|.:
Mosquito   412 AHQWFGNLVTCEWWDVTWLNEGFATYFEYFGTALVEPLWELDVQFVVEKLQAAMQTDGSLATHAM 476

  Fly   433 VQKVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEA 497
            ...|.:..:..|:||.|||.|||.|:||||..:.::.|:.|:..|:...||.....:...|.::.
Mosquito   477 THTVYTQTQAAAMFDAISYNKGGVVLRMLEHYLSSDVFQAAIREYVKDRQFATARPEQLFTVLDK 541

  Fly   498 VVTDLDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPIT 562
              .:.:....|..||.|.|:|::.|:...:| ..:||:||::|....||.       ..|.:|||
Mosquito   542 --RNANASAFMKPWTTQPGFPLVTVTSHGNG-VTLTQKRFIANGTDAEEK-------LLWPLPIT 596

  Fly   563 WFADDGSE----NSFIYDYDVDSVGIAVPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSP 623
             ||...||    ...|...:..::.:|..|:|.:..||..|.|||||||:|:||..:...|.:..
Mosquito   597 -FATKESEFESTTPTIVSSESHNITLANVSDVAYFILNNQQVGYYRVNYDEALWEKIGAALRSRA 660

  Fly   624 -ARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSL----- 682
             ....:.:|..:::|...||.|:.|.|...||:.:||.||.::.||..|.|...||...:
Mosquito   661 FGGIHVLNRAQIVDDLLNLAKADVLGYGKVLDLLSYLKQEMEYAPWLAAFNGFASLAPRIHPDDE 725

  Fly   683 -MFSEGYVSYLTYARSLIAGVYEEVGWTVDA--DNHLKNRLRVSILTAACALGVPDCLQQASERF 744
             :|::       |...::..|||.|.:....  |..|...||..:|...|..|..||.:.|.:.|
Mosquito   726 KLFTQ-------YLMDILTDVYEYVKFQAPTQYDRRLHTYLRRLVLDWTCRYGHDDCSKSAVKEF 783

  Fly   745 STFLENPTTRPSPDLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYL 809
            ..|..||..:..||||::||..|:::.:|: .:|.|..:|:....|:|:...::|:|.....:.:
Mosquito   784 ERFRTNPGVKVHPDLRQVVYCEGVRKGSSE-QFDFLLNIFLTTNVATEQQLTLFGMSCAPKEETV 847

  Fly   810 FDFLAQASSDESIVRSQDYFTCVQYI-----AANPVGEPVVWEFYREQWPQ-------------- 855
            ..|:...||.:  |||||..:.:..:     |..|....:|.  :..:|.:
Mosquito   848 NKFMNLVSSAD--VRSQDKASALSMLLNNQHALEPAASYLVQ--HSARWAEAHGGYRHVAMALGG 908

  Fly   856 -------LTTRFGLN----------NRNFGRLIA------QITANFASSVKLEEVQHFFSKYPES 897
                   ::.|..:.          .|....|||      ....||..:.: ||::.|.|:  ::
Mosquito   909 ILGRVNDVSVRTSIEQFAEASKDVLGREAYELIAAGLMQFDYNQNFTMNHR-EEIRGFLSQ--KA 970

  Fly   898 GAGANSRLEAVETIKYNI 915
            |:||:      ||:.||:
Mosquito   971 GSGAS------ETVIYNV 982

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	151/458 (33%)
		ERAP1_C	592..912	CDD:463368	96/370 (26%)
LOC11175863	XP_003436569.2	None