Protein Alignment CG8774 and LOC11175624

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_003436699.2
• Gene: LOC11175624 / 11175624
• VectorBaseID: AGAMI1_004280
• Length: 939
• Species: Anopheles gambiae
• Alignment Length: 942
• Identity: 282/942 - (29%)
• Similarity: 466/942 - (49%)
• Gaps: 74/942 - (7%)

  Fly    16 VVAFATATVVVAVQKAQLERDLRDVQDKIDVFEEWSGESRTRMKREDTTDYRLPTNLVPTHYELY 80
            ::...:|.:....:....||.|..: |.:.:.|..:.|.|          ||||:.:|||||:||
Mosquito    11 LIGLHSAAIAAHPKVQHSERKLNTL-DPVSLQEVAAQELR----------YRLPSYIVPTHYKLY 64

  Fly    81 WHPDLETGN--FTGQQRISIKVVEATNQIILHSYLLDITS--VYVLN-------REVEKFELEEE 134
            ....:.|||  ::|...|.:.:.:....|.:|...|.|||  :|..|       .|..::..:.|
Mosquito    65 LETQVHTGNRSYSGSVDIHLDIRQQAKTIYVHQRGLRITSNELYASNPNTNLTFLETLRYTEDAE 129

  Fly   135 RQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNEAGATRTISTTKFEPTYARQAFP 199
            |:|.:..:...|| .||..|.:.|.|:::....|.|.|:||:..|..:.:::|:|:...||.|||
Mosquito   130 REFAVFAIRRALA-PASYVLHLDFEGELRVDDDGFYLSSYLDANGTRKYVASTQFQAISARAAFP 193

  Fly   200 CFDEPAMKATFAITVVHPSGSYHAVSNMQ-QTESNYLGDYTEAIFETSVSMSTYLVCIIVSDFAS 263
            |.||||:|||..:.:.| ..||.|||||. ..|:..|.......|||:..||.||:..:||||..
Mosquito   194 CLDEPALKATVELGIKH-HPSYKAVSNMPIFAEAGDLDGNVVTYFETTPRMSIYLLAFLVSDFLY 257

  Fly   264 QSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPYP--LTKLDMAAIPDF 326
            ..        .|..:.:.||..:.||:..:|||.|..:.:...::..:||.  :.|:|..|:..|
Mosquito   258 TE--------NEAAAQRVYARPNAINQTLYALEAGVRIMDALDEHIGLPYRSYMPKVDQVALTQF 314

  Fly   327 ASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFA 391
            ::||||:|||..|||..||::|..::...:.:|...:|||..||||||::|.:||:.||||||||
Mosquito   315 SAGAMENWGLCKYREEVLLFEPGVTTYRAQTTITTIIAHEYVHQWFGNVITNEWWSYLWLNEGFA 379

  Fly   392 RYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIV-QKVESPDEITAIFDTISYEKGG 455
            ...::.|.:..:|:....:.|.:..:|.||:.||..|:.|:. .:..:.:.|.::||.::|.|||
Mosquito   380 TLYEFLGADMAYPERQYRDLFNVQVVQRVLITDAAESTRPMTFSRGATFNAILSLFDNVAYSKGG 444

  Fly   456 SVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDF---LTEVEAVVTDL----DIKKLMLTWTE 513
            ||::|...|:....:.:.:..|:..::|....||:|   |||....|..|    |:::.:.:|..
Mosquito   445 SVLQMFRLLLPDAAWRQMLRTYVQGNEFGTVNTDNFVAALTEAFDGVVSLPEGTDVERFVHSWVN 509

  Fly   514 QMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFADDGSENSFIYDYD 578
            |.|||||.|.:...|...::|.||.||.....:..       .|.:|.|......::::.:....
Mosquito   510 QAGYPVLEVRRSYRGEIILSQDRFYSNKIVNNDFT-------VWVIPYTMMEQGDAQDALLEWQW 567

  Fly   579 VDSVGIAVPSEV---QWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLNDAFA 640
            :.|..:.|||..   :||.:||||||:|||||:.|.|.:|||.|....|...:..|..|::|:|.
Mosquito   568 MTSKAVRVPSSTPNDEWILVNVNQTGFYRVNYDPSNWYMLIQTLLEDTAAIPMHSRAQLIDDSFH 632

  Fly   641 LADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYEE 705
            ||.:|:|..:|.|::..|:..||::.||..|:..|...|..:.....|:.|..:..:||..|:..
Mosquito   633 LARSNRLDLEIALELLGYVRHEREYPPWEAANRVLGYFHGRMRGQPDYILYELFVDTLIGDVFVT 697

  Fly   706 VGWTVDADNH--LKNRLRVSILTAACALGVPDCL---QQASERFSTFLENPTTRPSPDLREIVYY 765
            :..|..|.:.  |:..||..|.:.||.:.:..||   :.|.|| ..|...|.   .||:..:||.
Mosquito   698 LDITTVAPDERLLEKYLRQVISSWACRMEIESCLTATRDALER-EVFDAEPV---HPDVSAVVYC 758

  Fly   766 YGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIV--RSQDY 828
            ||::.:.: .::..||...:...:..|:..|:..|....:::.|..:|..|...|..|  .:::.
Mosquito   759 YGLRTAPT-VAFQYLFGKLLGSDNRGERQLLINALGCANDTEQLSSYLLAAIGGELQVNFNAEER 822

  Fly   829 FTCVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQITANFASSVK-LEEVQHFFS 892
            .:.:|.:.::..|...:.||..|.:..:.:..|.|      .:|.:..:.|:|.. |:|.|...:
Mosquito   823 LSILQSVLSSRQGVDALIEFLTENYTYVVSLLGPN------ALANLVQSIATSTNTLDEEQMLIA 881

  Fly   893 KYPE--SGAGANSRLEAVETIKYNIEWLSRNE 922
            ...:  |...|:....|..|...|:.|.|..|
Mosquito   882 LLEQLNSVLPASVSASARTTASINLAWPSTRE 913

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	153/459 (33%)
		ERAP1_C	592..912	CDD:463368	91/329 (28%)
LOC11175624	XP_003436699.2	None