Protein Alignment CG8774 and LOC11175602

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_003436572.2
• Gene: LOC11175602 / 11175602
• VectorBaseID: AGAMI1_012959
• Length: 935
• Species: Anopheles gambiae
• Alignment Length: 968
• Identity: 285/968 - (29%)
• Similarity: 468/968 - (48%)
• Gaps: 90/968 - (9%)

  Fly    15 AVVAFATATVVVAVQKAQLERDLRDVQDKIDVFEEWSGESRTRMKREDTTDYRLPTNLVPTHYEL 79
            |:|...|....|....:.|:.|           ..:..|:..|.:.|   ||||..::.||||::
Mosquito     8 ALVVLVTCACAVVSTASPLDPD-----------RYFLVEAEPRAQPE---DYRLNDDVWPTHYDI 58

  Fly    80 YWHPDLE-TGN-----FTGQQRISIKV-VEATNQIILHSYLLDITSVYVLNREVEKF------EL 131
            ...|.|| .||     |.|..:|::.. .:...||.||...:|||:..|..:.....      ..
Mosquito    59 EIKPYLEQEGNKAQFTFDGSAKITVSTQKQNVMQIKLHMARMDITAWSVTRKSDNTIIPTLPQTY 123

  Fly   132 EEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNEAGATRTISTTKFEPTYARQ 196
            ::|.|.|.:.|:..|..:....|...:.|.|.|.:.|.|.|.|. |.|....:.:|:|:.|:||:
Mosquito   124 DQETQILTLPLSSALQANVEYVLSFTYVGNMDDDMHGFYRSYYW-EDGVKVWMGSTQFQQTHARR 187

  Fly   197 AFPCFDEPAMKATFAITVVHPSGSYHAVSN--MQQTESNYLGDYTEAIFETSVSMSTYLVCIIVS 259
            ||||||||..||||.:.:.|.: .|:..||  :..|....:| .|...|..:.|||:||:..||:
Mosquito   188 AFPCFDEPRFKATFQLKINHKT-QYNVYSNTAIVGTAVAEVG-RTLTTFGVTPSMSSYLIAFIVA 250

  Fly   260 DFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPY----PLTKLDM 320
            .:.          |.:...|...|.....|:.:::|:.|..:.:...::...||    .:|::.|
Mosquito   251 PYQ----------INDRDGMGILARPQAQNQTQYSLDVGIKLLKALDEWLDYPYASMPAMTRMYM 305

  Fly   321 AAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLW 385
            ||:|||::||||:|||:||||..:||....|::..:|.||..::|||||||||:|||.:||:..|
Mosquito   306 AAVPDFSAGAMENWGLLTYREANILYRSDDSTSMQQQRIATVISHEIAHQWFGDLVTCEWWDVAW 370

  Fly   386 LNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPDEITAIFDTIS 450
            ||||||||.:|.....|..:|...:||.:..||.|:..|:..|:||:...|.:..|.:||||:|:
Mosquito   371 LNEGFARYYEYYATALVETNWDFEDQFVVAQLQSVMQMDSLRSTHPMTHPVYTQAESSAIFDSIT 435

  Fly   451 YEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVVTDLDIKKLMLTWTEQM 515
            |.||..|:||:|..:..|.|:.|:..|:....|..|..:|..:.:...  |.:.:..|..||.|.
Mosquito   436 YNKGAVVLRMMEHYLTTETFKTALRAYIKDRAFKTTRPEDLFSALNRY--DPNARSYMEPWTVQP 498

  Fly   516 GYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFADDGSENSFIYDYDVD 580
            |||::.|:. .|..|.|||:|||.|...:.|..:       |.:||| ||...||.|........
Mosquito   499 GYPLVTVTS-HDTGFTVTQKRFLVNEPDHNEQTA-------WPLPIT-FATKASEFSTTRPAFYT 554

  Fly   581 SVGIAVP----SEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSP-ARFEIADRGHLLNDAFA 640
            .:...:|    |:|::..||..|.|||||||:..||..:.:.|.:.. ....:.:|..:::|.|.
Mosquito   555 GMTFEIPMQGASDVEYFILNNQQVGYYRVNYDAILWGKISKALHSEGFGGIHVLNRAQIVDDLFN 619

  Fly   641 LADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYEE 705
            ||..:.:.|...|::..||.:|.::.||..|.|.|.:|.|.: .::....:..:...:.:..|:.
Mosquito   620 LARGDVVPYGTALEILEYLKEETEYAPWLAAVNGLTTLSRRI-HADDEKLFAAHILDIFSKAYDI 683

  Fly   706 VGWTVD--ADNHLKNRLRVSILTAACALGVPDCLQQASERFSTFLENPTTRPSPDLREIVYYYGM 768
            |.:...  .:..:...:|.::|..||..|..:|.:.|...|..:.:||:.:..||||::||..|:
Mosquito   684 VKFQAPTATERRIFTYMRQNVLQWACNYGHEECSKAAVAEFHRYHQNPSVKIHPDLRQVVYCEGI 748

  Fly   769 QQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQ 833
            ::. |...::.|:..::....|:|:|.::.||....:|:.:...|...:|..  |||||......
Mosquito   749 RKG-SMEEFEFLWNQYLTTNMATEQLLILQGLGCASSSELITIMLDAITSPH--VRSQDKSNAFT 810

  Fly   834 YIAANPVGEPVVWEFYREQ---WPQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQHFFSKYP 895
            |:..|....|.|..:.::.   |       ..::.::.. :|....|..:.:|.:..:...|.:.
Mosquito   811 YVINNLYTLPHVSRYLQQNHAIW-------AASHGSYAN-VASAFNNVLARLKSDSERDVISAFI 867

  Fly   896 ESG------AGANSRLEAVETIKYNIEWLSRNEADITDWL-----SGTASPLTKKNQL 942
            ||.      |..:|....:|..:.|.::..||..:|.::|     .|.|:.|...:.:
Mosquito   868 ESNKNILGQAAYDSIKSGLEDYETNKQFTLRNRDEIHEFLDNKINGGAATILANVSMI 925

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	157/456 (34%)
		ERAP1_C	592..912	CDD:463368	78/331 (24%)
LOC11175602	XP_003436572.2	None