Protein Alignment CG8774 and LOC11175588

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_061502291.1
• Gene: LOC11175588 / 11175588
• VectorBaseID: AGAMI1_013558
• Length: 958
• Species: Anopheles gambiae
• Alignment Length: 836
• Identity: 253/836 - (30%)
• Similarity: 408/836 - (48%)
• Gaps: 90/836 - (10%)

  Fly    42 DKIDVFEEWSGESRTRMKREDTTDYRLPTNLVPTHYELYWHPDL--ETGNFTGQQRISIKVVEAT 104
            |:.||....:..|.....|:..:.|.||...|||||.:....|:  :...|:...||.:.|:..|
Mosquito    45 DQGDVLYHAASVSSNAATRDVDSTYFLPNTTVPTHYSISLRTDIHNDVRTFSAITRIYLTVLAPT 109

  Fly   105 NQIILHSYLLDITSVYVLNR-----------EVEKFELEEERQFLIITLTEELAVDASITLGIIF 158
            :.|::|...|:|.|| .|.|           :...:.::..|:.:.......|.: .:..|.:.:
Mosquito   110 DLIVMHVQELNIASV-ALYRIASTGGNEIWIDSPTYMIDIVREHVTFRTAGMLPL-GNYALEVAY 172

  Fly   159 GGQMKDKLVGLYSSTYLNEAGATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHA 223
            .|.|::...|...|.|.|||...|::.||.|:.|.||:.|||:||||:||||.:.:.| ..:|.|
Mosquito   173 TGSMRNYQSGYLVSRYRNEANEWRSVGTTHFQATLARRVFPCYDEPALKATFDLKITH-HRTYTA 236

  Fly   224 VSNMQQTESNY---LGDYTEAIFETSVSMSTYLVCIIVSDF-----ASQSTTVKANGIGEDFSMQ 280
            ::||....::.   ..:|..:.||.:..|||||:...|:||     ......|::|  .:|.:|
Mosquito   237 IANMPLAGTDIDPNDREYLVSRFERTPLMSTYLLAFAVTDFKTLRNGQHEIVVRSN--AQDDAM- 298

  Fly   281 AYATSHQINKVEFALEFGQAVTEYYIQYYKVPY--PLTKLDMAAIPDFASGAMEHWGLVTYRETA 343
                        :||..|..:.|....|.::.|  .:.|:...|:||..:||||:||||||.|.:
Mosquito   299 ------------YALTVGSTILERLGSYLELSYYDYMPKMTSIAVPDRGTGAMENWGLVTYGEPS 351

  Fly   344 LLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGM 408
            |||.|:.::..|::.:...:|||.||||||:||:.:.|:.:||:||||...:|.......|....
Mosquito   352 LLYSPAVNTYRNRKRVTTVIAHEYAHQWFGDLVSPRSWDFIWLSEGFATLYEYLATRLAEPGDEY 416

  Fly   409 LEQFQIVALQPVLLYDAKLSSHPIVQKVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEA 473
            .|.|.:..:|...|.||.....||..:..:..|::::||.|:|:|.|||:.|...::|..::.:.
Mosquito   417 WELFSVEVVQRAFLQDANEQIRPINWQAATQAEVSSLFDIIAYQKAGSVLNMFRNVLGESEWRQG 481

  Fly   474 VTNYLVKHQFNNTVTDDFLTEVEAVVTDLDI-------KKLMLTWTEQMGYPVLNVSKV-ADGSF 530
            :|.||....::....::....::..|...||       :.|:.:||:..|:|||||.:: .||..
Mosquito   482 LTQYLTDRGYDAATEENLALHLQRAVEGKDILPPTANVRDLLASWTDAPGFPVLNVYRLYRDGMM 546

  Fly   531 KVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFADDGSENSFIYDYDVDSVG----------IA 585
            .::|:|||....    .|:    |:.|.:|..:    ..|:|..: ||:.:.|          ..
Mosquito   547 ILSQERFLEQSV----LPT----GHVWHIPFNY----AYESSATF-YDLTTAGWLSSRAAKLETP 598

  Fly   586 VPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLNDAFALADANQLSYK 650
            ||.: :|:..|..|||||||||:...|.||.|.|..:......|:|..|::|||.||.|:.|...
Mosquito   599 VPDD-EWVVFNKQQTGYYRVNYDRRNWDLLAQALMANRNAIHRANRAQLIDDAFNLARADLLDMA 662

  Fly   651 IPLDMTAYLAQERDFVPWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVY-----EEVGWTV 710
            :.|.:..||..|||:.|||.|...|..|:..:..:|...::|.|...||..||     :.||
Mosquito   663 VVLRLMRYLRAERDYAPWYAADKVLTYLYDKVRATEHEHAFLVYVDELIEEVYATLSVDTVG--- 724

  Fly   711 DADNHLKNRLRVSILTAACALGVPDCLQQASERFSTFL----ENPTTRPSPDLREIVYYYGMQQS 771
            ..::.|...||..|...||.:|..|||:::.......|    ...:....||:|.:||.||:||.
Mosquito   725 QGESTLYKYLRQLITGWACRIGYKDCLERSRAALRKELLPGQGESSVAVHPDVRAVVYCYGLQQD 789

  Fly   772 TSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFDFLA----QASSDESIV 823
            ::: .:..:||..:|..:.:|:..|:..|...||:..:...||    .|:.|.:.|
Mosquito   790 SAE-EFQLIFQRLMASRNQAERTDLIDALGCARNADSITSLLATIVFSAAPDTTFV 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	139/467 (30%)
		ERAP1_C	592..912	CDD:463368	80/245 (33%)
LOC11175588	XP_061502291.1	None