Protein Alignment CG8774 and lvrn

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_031748993.1
• Gene: lvrn / 100496094
• XenbaseID: XB-GENE-980447
• Length: 990
• Species: Xenopus tropicalis
• Alignment Length: 1027
• Identity: 286/1027 - (27%)
• Similarity: 467/1027 - (45%)
• Gaps: 148/1027 - (14%)

  Fly     4 SGYWLQ----VVLSWAVVAFATATVVVAVQKA---QLERDLRDVQDKIDVFEE-------WSGES 54
            ||::|.    |:|:..:.|.....:::....|   |....:.|....::...|       |:
 Frog     7 SGFYLSRTSAVLLTLLLAALILVVIILGALYARTPQRSHHICDTSTSLENIAEPTDRPGIWN--- 68

  Fly    55 RTRMKREDTTDYRLPTNLVPTHYELYWHPDL---ETGN--FTGQQRISIKVVEATNQIILHSYLL 114
                      :.|||.||||.||:|...|.:   |.||  |:||..|:|..||.|:.::|||..|
 Frog    69 ----------NLRLPHNLVPLHYDLELWPRMEEDEEGNYPFSGQVNITISCVEDTDVVLLHSIQL 123

  Fly   115 DITSV--------YVLNREVEK--------------------FELE------------EERQFLI 139
            :.:.|        .::.:.:||                    :::.            |:..:::
 Frog   124 NFSDVGLRLLGNKTIMYQSMEKDGKHNALQEGRAYKRLQDPTYDIHGGNVSINNVWTFEDHSYVV 188

  Fly   140 ITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNEAGATRTISTTKFEPTYARQAFPCFDEP 204
            :.|.|.|.......|.:.:.|.::.. ..|: .|:..:....:.:..:..||.|||..:||||||
 Frog   189 LELNERLVAGNLYLLELNYTGFIRQN-TALF-ITHYKDFNIDKAVVASLLEPEYARAVYPCFDEP 251

  Fly   205 AMKATFAITVVHPSGSYHAVSNMQQTESNYLGD-----YTEAIFETSVSMSTYLVCIIVSDFASQ 264
            |:||||.|.:||.| ||.|:|||.....:...|     :|...|:|:..||||:...::.||...
 Frog   252 ALKATFKIRLVHNS-SYVALSNMPAVAVSEREDIDGSIWTVTTFDTTPKMSTYITAFVICDFDYV 315

  Fly   265 STTVKANGIGEDFSMQAYATSHQINK--VEFALEFGQAVTEYYIQYYKVPYPLTKLDMAAIPDFA 327
            :.|.:.|.|      :.:|....:.|  ...||.....:..|....:.|.|||.|.|..|:||..
 Frog   316 NITERGNEI------RVWARKEVVQKGFASLALSIAGPLLSYMEDLFNVSYPLQKTDFVALPDLD 374

  Fly   328 SGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFAR 392
            ..|||:|||:|:.|.||:|||...|:.:|...:..::|||||||||||||||||.|||||||||.
 Frog   375 VEAMENWGLITFIEEALIYDPRQKSSNSKFRTSLIVSHEIAHQWFGNLVTMKWWTDLWLNEGFAT 439

  Fly   393 YMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPDEITA--IFDTISYEKGG 455
            ||:|.|:..:.....:.|.|.:..|||:...|....:..:..|.|...|..:  :|:..:|:||.
 Frog   440 YMEYFGITFLDSKLELNELFTMHNLQPIFERDVGAHAKTVSMKEEELYEADSSHMFNEFTYDKGS 504

  Fly   456 SVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVVTDLD-------IKKLMLTWTE 513
            :::|||.:.:..:.|.:.:::||....|:|...||....::..:...|       ::.:|.:||.
 Frog   505 ALVRMLSSFLTEKLFIKGISSYLKTFSFSNVDQDDLWNHLQMFIDHQDEVRLPTTLRHIMQSWTW 569

  Fly   514 QMGYPVLNV----SKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFADDGSENSFI 574
            |.|.|:|.:    .::|:..||..         :.:...|||  .:.|.||:||..:...:.|..
 Frog   570 QRGIPLLTLDTTTGELAEELFKTD---------NTDNITSDS--NHTWIVPVTWMKNGTKQISLW 623

  Fly   575 YDYDVDSVGIAVPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLNDAF 639
            .|.......:...:..:||.||:|.|||||.||.:..|..|.:||..:|......:|..|:.|||
 Frog   624 LDSKSKVFPVLTTAADEWIVLNINVTGYYRTNYNKENWNRLAKQLEANPKVVPTVNRIQLIEDAF 688

  Fly   640 ALADANQLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYE 704
            .||......:...|.:|.||.:|.:...||.....:.|....|:....:..:..|....|:.:|:
 Frog   689 ILARYGYTDHGTALSLTKYLEKEEEINVWYTVLKHVTSSDYPLITYTNFPLFKKYILKRISPIYQ 753

  Fly   705 EVGWTV------DADNHLKNRLRVSILTAACALGVPDCLQQASERFSTFLENPTTRPSPD-LREI 762
            ....::      .||::........||..||:.|:.||||.|.:.::|:::|.:....|: :|..
 Frog   754 RFANSIRRNFDEAADDYFIQVHIELILKTACSFGLQDCLQLAHQLYATWMKNCSGNVIPESIRNP 818

  Fly   763 VYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQD 827
            :..|.:... .:..|:..::: |.:::..|:..|.|.||..:....|..:|..:..    :....
 Frog   819 ICCYAIANG-GEKEWEFAWKM-VNKSEEIERDLLFYALSCTKEPWLLHRYLEYSLE----MYKSS 877

  Fly   828 YFTCVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNR--NFGRLIAQITANFASSVKLEEVQHF 890
            .||....:..|.:|..:.|||.:|.|.::...||..:.  .:..|:....:..||.::.:|:|.|
 Frog   878 AFTIFLDVIKNEIGRHIAWEFLKENWQRIHDIFGPRDTVDFYTVLLPTFASKAASDLQFQEIQLF 942

  Fly   891 FSKYPESGAGANSR---LEAVE---------TIKYNIE---WLSRN--EADI 925
            .:    :....|.|   ||.||         |.|.|.|   ||.||  ||:|
 Frog   943 IN----TTINENQRERILEQVENKWRKSLGWTSKINDEILTWLQRNADEAEI 990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	154/498 (31%)
		ERAP1_C	592..912	CDD:463368	86/340 (25%)
lvrn	XP_031748993.1	M1_APN-Q_like	79..568	CDD:341064	153/497 (31%)
		ERAP1_C	641..945	CDD:463368	79/313 (25%)