Protein Alignment CG8774 and anpep

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_031755081.1
• Gene: anpep / 100492262
• XenbaseID: XB-GENE-981369
• Length: 977
• Species: Xenopus tropicalis
• Alignment Length: 991
• Identity: 336/991 - (33%)
• Similarity: 528/991 - (53%)
• Gaps: 76/991 - (7%)

  Fly     2 FLSGYWLQVVLSWAVVAFATATVVVAVQKAQLERDLRDVQDKIDVFEEWSGES------------ 54
            ::|...|.|.:.:||.|.:| .:.:||..:|.:....||....:.....||.|
 Frog     6 YVSKLVLAVGIIFAVAAVST-IIALAVVYSQEKGKNNDVAKPPETTTSSSGTSTATTTTTATATA 69

  Fly    55 --RTRMKREDTTDYRLPTNLVPTHYELYWHPDLETGN-----FTGQQRISIKVVEATNQIILHSY 112
              .|....:....||||..|.|.||::...|.|....     |.|:........:||:.||:||.
 Frog    70 TATTAQSNDPWNKYRLPKTLSPVHYDVELQPFLVKNADGLYVFRGKSTAFFICNDATDLIIIHSN 134

  Fly   113 LLDITSVYVLNREVE---------KFELEEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVG 168
            .|:.|.....:.:::         ....::::|||::.....|.......|...|.|::.|.|.|
 Frog   135 KLNHTKFNSFDAKLQDGATDVALKSTFFQKDKQFLVVQAAANLVPGKQYGLYTEFVGELADDLAG 199

  Fly   169 LYSSTYLNEAGATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESN 233
            .|.|.|| |.|.|:.|:||:.:...||:||||||||||||||.||:.:.. .|.|:|||::.:.:
 Frog   200 FYRSEYL-EDGVTKIIATTQMQAPDARKAFPCFDEPAMKATFNITLKYRQ-PYKAMSNMREIDRS 262

  Fly   234 YLGD----YTEAIFETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQI---NKV 291
            .:.:    :|.:.|:.:..||:|||..|||:|.:......|...|    :|.:.....|   |:.
 Frog   263 TVTEDGQQWTVSKFDKTPKMSSYLVAFIVSEFEAVGDPGNATVTG----VQIWGRKKAIQDENQG 323

  Fly   292 EFALEFGQAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANK 356
            |:||...:.:.:::.:||:.||||.|.|..|:|||::||||:||||||||||||:|...||..||
 Frog   324 EYALSVTKPILDFFAEYYRTPYPLPKSDQVALPDFSAGAMENWGLVTYRETALLFDDQVSSIGNK 388

  Fly   357 QSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVL 421
            :.:...:|||:||||||||||::||||||||||||.|::|.|.:...|:|.:.:...:..:..|:
 Frog   389 ERVVTVIAHELAHQWFGNLVTIRWWNDLWLNEGFASYVEYLGADKAEPNWNIKDLIVLNDVHRVM 453

  Fly   422 LYDAKLSSHPIVQK---VESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQF 483
            ..||..||||:..:   |.||.||:|:||:|:|.||.||||||...:....|.:.:.:||...::
 Frog   454 AVDALASSHPLTSREDEVNSPSEISALFDSIAYSKGASVIRMLSEFLTEPLFVDGLASYLKGFEY 518

  Fly   484 NNTVTDDFLTEVE-------AVVTDLDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNP 541
            :|||..|..|.::       ||...|.||.:|.||..|||:||:   |:...:..|||:.||.:|
 Frog   519 SNTVYSDLWTHLQWAVNNQTAVKLPLPIKDIMDTWVLQMGFPVV---KIDTATGVVTQKHFLLDP 580

  Fly   542 ASYEEAPSDSAYGYKWSVPITWFADDGSENSFIYDYDVDSVGIAVPSEVQWIKLNVNQTGYYRVN 606
            .|....|  |.:.|||.|||::......:|.::.: :.::|.....:...|:.:|:|.|||||||
 Frog   581 DSVVTRP--SPFDYKWKVPISYKISSKEDNIWLQN-ESETVEDFKITGNDWLLVNLNVTGYYRVN 642

  Fly   607 YEESLWALLIQQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVA 671
            |:::.|:.|:.||.||.....:.:|..:::|||.||.|.|::....||.|.|::.:|:::||..|
 Frog   643 YDDNNWSRLLNQLQTSHQAIPVINRAQIIDDAFNLARAKQITTIQALDTTKYISADREYMPWQAA 707

  Fly   672 SNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYE----EVG-WTVDADNHLKNRLRVSILTAACAL 731
            .:.|....:....:|.:.....|.:..:..::|    |.| ||....:.......::.|:.||:.
 Frog   708 LSGLSYFTQMFDRTEVFGPMKKYMKMQVNPLFEYFKQETGNWTNRPVSLTDQYCEINTLSTACSY 772

  Fly   732 GVPDCLQQASERFSTFLENP-TTRPSPDLREIVYYYGMQQSTSQS---SWDQLFQLFVAETD-AS 791
            .:.|||:.|||.||.::..| .....|:||..||...:.|...|.   .||: |||    || |.
 Frog   773 DIEDCLKFASELFSQWMATPQQNNIHPNLRTNVYCTAVAQGGEQEWNFVWDR-FQL----TDIAQ 832

  Fly   792 EKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQL 856
            |:.||...|:..:....|..|| :.|.|.:::|.||..:.:..:..||:|:.:.|:|.|.:|..|
 Frog   833 EQDKLRAALACSKEPWILNRFL-EYSLDPTMIRRQDAVSTISSVVNNPIGQSLAWDFVRAKWKTL 896

  Fly   857 TTRFGLNNRNFGRLIAQITANFASSVKLEEVQHFFSKYPESGAGANSRL--EAVETIKYNIEWLS 919
            .:.||.::.:||.||.::|..|::..:|:::..|.:.....|.|..|:.  :|:|..|.||.|::
 Frog   897 YSMFGESSFSFGNLIERVTRRFSTEFELQQLLQFKADNQNPGFGTASQALEQAIEKTKANINWVN 961

  Fly   920 RNEADITDWLSGTASP 935
            :|:|.:..|......|
 Frog   962 QNKAAVKKWFEDAVVP 977

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	180/468 (38%)
		ERAP1_C	592..912	CDD:463368	103/331 (31%)
anpep	XP_031755081.1	M1_APN-Q_like	92..555	CDD:341064	180/468 (38%)
		ERAP1_C	628..955	CDD:463368	103/332 (31%)