Protein Alignment CG8774 and lnpep

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_002933474.1
• Gene: lnpep / 100216271
• XenbaseID: XB-GENE-950921
• Length: 1024
• Species: Xenopus tropicalis
• Alignment Length: 969
• Identity: 321/969 - (33%)
• Similarity: 498/969 - (51%)
• Gaps: 115/969 - (11%)

  Fly    16 VVAFATATVVVAVQKAQLERD-----------LRDVQDKIDVFEEWSGESRTRMKREDTTDYRLP 69
            ::|.:..|||..:.|....:|           :..:.....|| .|:..             |||
 Frog   118 IIAVSVVTVVYLLPKCTFTKDGCHEKKHPLELVYPIATNGKVF-PWAKS-------------RLP 168

  Fly    70 TNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYV-------LNREVE 127
            .::.|.||.|..|||:.|..|.|..:|.:.:..::|.|:|||..|.|...:|       ::.||.
 Frog   169 NSIKPVHYVLTLHPDMTTMYFAGTVQIKLNITASSNNIVLHSSGLRIIKAHVSVTEGTTMDAEVL 233

  Fly   128 KFELEEERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNEAGATRTISTTKFEPT 192
            ::...||   :.|.|.|.|.......|.|.:.........|.|...|: |.|..|:::.|:|||.
 Frog   234 EYPTFEE---IAIILPESLPKGKECLLTIQYTSNFSSTYYGFYKIDYM-EKGNKRSLAATQFEPL 294

  Fly   193 YARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESNYLGD---YTEAIFETSVSMSTYLV 254
            .||:.||||||||.|:||.|.::. :.|..::|||.:.:::.:.|   ..|  :.|||:||||||
 Frog   295 AARKVFPCFDEPAFKSTFQINIIR-NQSMISLSNMPKAKTSTMSDGLLLDE--YSTSVNMSTYLV 356

  Fly   255 CIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPYPLTKLD 319
            ..||.|.  ::||.:.|    |..:..||...::::|::||:....:..:|..||.:.|||.|||
 Frog   357 AFIVGDI--KNTTQETN----DTLVSVYAVPEKMDQVKYALDSAMKLLYFYSNYYNIAYPLKKLD 415

  Fly   320 MAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTMKWWNDL 384
            :.|||||.:||||:|||:|:|||||||....||.|:||||...:|||:|||||||||||:|||||
 Frog   416 LVAIPDFQAGAMENWGLITFRETALLYKEDSSSVADKQSITKVIAHELAHQWFGNLVTMEWWNDL 480

  Fly   385 WLNEGFARYMQYKGVNAVHPDWGMLEQF---QIVALQPVLLYDAKLSSHPIVQKVESPDEITAIF 446
            |||||||.||:|..::::.|:......|   :..|||.    |:..:||||...::||::|..:|
 Frog   481 WLNEGFATYMEYVSMSSLFPELNSENSFLKMRFTALQK----DSLNASHPISTDIQSPEQIEEMF 541

  Fly   447 DTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVVTDL--DIKKLML 509
            |.:||.||.|::.||:..:..:.|...:..||..||:.:| |.|.|.:...|||:.  ::|.:|.
 Frog   542 DDLSYIKGASILLMLQAFLSEDVFHHCIMEYLQAHQYGST-TSDSLWDSMNVVTNKNPNVKNMMK 605

  Fly   510 TWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFA------DDG 568
            |||::.|||::...:..: ...|.|:|||..| |.:.|.:.|..   |.:|:|:..      :..
 Frog   606 TWTQKAGYPLVTALRKGE-EITVQQERFLRTP-SPDHATNASTV---WHIPLTYVTRKCSGIEPQ 665

  Fly   569 SENSFIYDYDVDSVG-IAVPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRG 632
            .:|.::..   :..| |.|.||..|:|.|||.||||.|:|....|..||:||.........:||.
 Frog   666 CDNIYLLK---EVTGRINVSSEFPWVKFNVNMTGYYIVDYGADGWDALIKQLLRDHTVLHSSDRA 727

  Fly   633 HLLNDAFALADANQLSYKIPL----DMTAYLAQERDFVPWYVASNKLRSLHRSLM---------- 683
            :|::|.|.||...    |:||    ::..|||.|.:..|...|.|:...:|..|:
 Frog   728 NLIHDIFMLAGVG----KVPLAKAFELLGYLANETNSAPITQALNQFYHIHGILLKRGLDELSDK 788

  Fly   684 -FSEGYVSYLTYARSLIAGVYEEVGWTVDADNHLKNRLRVSILTAACALGVPDCLQQASERFSTF 747
             ...|    |....:||...:|:.|...:.:      ||.|:|..||:.|:..|:.:|.|.|:.:
 Frog   789 VMERG----LKLLSNLINQTWEDEGTLAERE------LRSSLLDFACSSGLQSCVDKAMELFNIW 843

  Fly   748 LENPTTRPSPDLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFDF 812
            ..|.|..|: |:.::|:..|   :.:...|..|:..:......:||.|::..|:...|.:.| .:
 Frog   844 RLNNTRIPT-DVMKVVFKVG---AKTAEGWAFLWDKYTTSLYETEKRKILEALASTDNGRKL-QW 903

  Fly   813 LAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQITAN 877
            |.|.|.|..::|||:....:.:|:....|..:.|||.::.|..:|.:|...:.....:::..|.:
 Frog   904 LMQESLDGGLIRSQELPAVLGFISKGSPGYLLAWEFAKQNWDLITQKFMPGSFPIQSIVSTTTYH 968

  Fly   878 FASSVKLEEVQHFFSKYPESGAGANSRL----EAVETIKYNIEWLSRNEADITDWLSGT 932
            |::...|.||..||:    |..|.:..:    |||||||:||||:..|...:..||..:
 Frog   969 FSTDTHLNEVIAFFN----STKGKSREMWCVKEAVETIKFNIEWMKNNLDSLKTWLQSS 1023

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	182/452 (40%)
		ERAP1_C	592..912	CDD:463368	95/338 (28%)
lnpep	XP_002933474.1	M1_APN-Q_like	174..609	CDD:341064	182/452 (40%)
		ERAP1_C	687..1003	CDD:463368	95/338 (28%)