Protein Alignment CG8774 and erap2

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_001116524.1
• Gene: erap2 / 100144556
• ZFINID: ZDB-GENE-080402-6
• Length: 931
• Species: Danio rerio
• Alignment Length: 913
• Identity: 314/913 - (34%)
• Similarity: 470/913 - (51%)
• Gaps: 76/913 - (8%)

  Fly    67 RLPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYVLNREVEKFEL 131
            |||..:||.||.|..||:|.|.:|||..:|.|.|...||.::|||..|.|.:..||: |.|....
Zfish    44 RLPNYIVPVHYHLLIHPNLTTLSFTGSVKIEIDVKNNTNWVVLHSKNLKIYTATVLD-EHEAHLS 107

  Fly   132 EEERQFLIITLTEELAVDAS--ITLG------IIFGGQMKDKLVGLYSSTYLNEAGATRTISTTK 188
            |:....|...|.|::|:.:.  :|.|      :.||..:.|...|.|.|||..::|.||.:::|.
Zfish   108 EKTLSVLEYPLHEQIAIFSPKILTSGEKYFLYLEFGAPLSDGFHGFYKSTYRTKSGETRVLASTH 172

  Fly   189 FEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNM--QQTE--SNYLGDYTEAIFETSVSM 249
            ||||.||.|.||||||..||.:.:. :....|:.|:|||  :||.  ||.|   .|..||.||.|
Zfish   173 FEPTSARMALPCFDEPVFKANYTVR-IRRGPSHIALSNMPLEQTVEISNGL---FEDHFEASVKM 233

  Fly   250 STYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPYP 314
            |:||:..||.||.|.| .:.|.||    ::..||...:.::..:|||....:.|:|.||:.:.||
Zfish   234 SSYLLAFIVCDFKSVS-GLTATGI----NISIYAVPEKWHQTHYALEAALRLLEFYEQYFNILYP 293

  Fly   315 LTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIAHQWFGNLVTMK 379
            |.|||:.|||||.|||||:|||.|||||:|||||..||.::|..:...:.||:|||||||||||.
Zfish   294 LPKLDLIAIPDFESGAMENWGLTTYRETSLLYDPDISSASDKLWVTMVIGHELAHQWFGNLVTMD 358

  Fly   380 WWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPDEITA 444
            ||||:||||||||||:...|.||:|:..:.:.| :......:..|:..||.||....|:|.:|..
Zfish   359 WWNDIWLNEGFARYMESVSVEAVYPELKVEDHF-LDTCFGAIGRDSLNSSRPISSLAENPTQIKE 422

  Fly   445 IFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVVTD-------- 501
            :|||:|||||..::.||...:..|.|:..:..||.:..:.|...:|....:....::
Zfish   423 MFDTVSYEKGACILHMLRHFLTDEGFQSGIIRYLRRFSYCNARNEDLWDSLIKTCSEEDFAAGEY 487

  Fly   502 ------------------LDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAP 548
                              :|:||:|.|||.|.|.|::.|.:... ...:.|:|||.     ...|
Zfish   488 CYSSAQATKNAYRFAGEHVDLKKMMNTWTLQKGIPLVTVKRQGK-KLHIGQERFLK-----IVLP 546

  Fly   549 SDSAY-----GYKWSVPITWFADDGSENSFIYDYDVDSVGIAVPSEVQWIKLNVNQTGYYRVNYE 608
            .|.::     ||.|.:|:| :....||:...:..|..|..:.:...|.|:|||.:..|||.|:|:
Zfish   547 DDPSWHSLQDGYLWHIPLT-YKTSHSEHEVKHILDKKSDVLLLDEHVDWVKLNTDMNGYYIVHYD 610

  Fly   609 ESLWALLIQQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASN 673
            |..|..|.:.|..:.......||..|:::||.|..|.:||....||:.|||..|...||......
Zfish   611 EEGWNALTELLKVNHTALSFKDRASLIHNAFQLVTAGRLSLDRALDLIAYLKSETHNVPLLQGLG 675

  Fly   674 KLRSLHRSL---MFSEGYVSYLTYARSLIAGVYEEVGWTVD---ADNHLKNRLRVSILTAACALG 732
            .|:|.::.:   ..::...:..||.......|.::..|:.|   :|    .|||..:|:.||.|.
Zfish   676 YLQSFYKLIEKRKIADVTHNLKTYILQYFKDVIDKQSWSDDGMVSD----RRLREDVLSLACDLD 736

  Fly   733 VPDCLQQASERFSTFLENPTTRPSP-DLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKL 796
            .|.||::|...|.:::::..|...| |:.|.||..|.|   ..|.|..|.:.:......:||.|.
Zfish   737 YPPCLEKAERLFVSWVKSNGTISLPTDVSETVYMVGAQ---DDSGWVYLLRQYGVSMCETEKSKF 798

  Fly   797 MYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTRFG 861
            :..|:..::|:.| ..|.|...:.:::::|:..:.:..:|.||||..:.|:|.::.|.:|..:|.
Zfish   799 LSALTSSKDSEKL-SRLLQLGMEGTVIKTQNLPSLIYMVARNPVGHFLAWDFVKKHWNELVEKFP 862

  Fly   862 LNNRNFGRLIAQITANFASSVKLEEVQHFFSKYPESGAGANSRLEAVETIKYNIEWLSRNEADIT 926
            :.:.....:|......|:|:.:|.||:.||....|..:.......|.|.::.||.||.||...:.
Zfish   863 MGSFGIRNIIVGTVTQFSSAEELREVESFFKSIQEQVSQLRIIQVATENVEKNIVWLKRNLETLR 927

  Fly   927 DWL 929
            .||
Zfish   928 TWL 930

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	189/475 (40%)
		ERAP1_C	592..912	CDD:463368	91/326 (28%)
erap2	NP_001116524.1	M1_APN-Q_like	52..517	CDD:341064	189/475 (40%)
		ERAP1_C	594..913	CDD:463368	91/326 (28%)